"This lecture series, part of the ""Computational Systems Biology"" course, focuses on the mathematical modeling of biological systems. It introduces various...

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This practical guide speaks to two audiences: those who read and those who conduct research. Clinicians are medical detectives by training. For each patient, they assemble clinical clues to establish ...

Seeking a Postdoc to develop computational toolkits to enable large-scale studies of single-cell and spatial 'omics and statistical genetics

Turing Drawings

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A set of functions to run code with safely and temporarily modified global state. Many of these functions were originally a part of the devtools package, this provides a simple package with limited de...

Single-cell RNA sequencing allows the quantitation of gene expression at the individual cell level, enabling the study of cellular heterogeneity and gene expression dynamics. Dimensionality reduction ...

See full course materials and topical outline here: https://github.com/rmcelreath/stat_rethinking_2024

Regression experts consistently recommend plotting residuals for model diagnosis, despite the availability of many numerical hypothesis test procedures designed to use residuals to assess problems ...

Here, using mathematical modeling and an in vitro deadenylation system, the authors quantitatively demonstrate the effect of non-adenosines in the poly(A) tail and exemplify how tail sequence regulate...