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Patrick Kenney, MD MS

@patrickkenney.bsky.social
2K followers 3K following 88 posts

Med-Peds ID, phage discoverer, more importantly husband and dad. Posts are my own. #medsky #IDsky #askmedpeds #phagetherapy

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Patrick Kenney, MD MS @patrickkenney.bsky.social · 13/09/2026
It was really nice to see pediatrics addressed directly here - the extrapolation from other adult guidelines we have to do sometimes is difficult
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Richard Easther @rjme.bsky.social · 07/09/2026
Astonishing, heartwarming story in the NY Times (and, for those who like a "New Zealand mentioned", Vaughn Jones is the only ever kiwi Fields Medalist) www.nytimes.com/2026/09/06/s...
nytimes.com
The 92-Year-Old Mathematician and the Teenage Apprentice (Gift Article)
Joan Birman thought her major discoveries were behind her. Then came an email from a young neighbor — a girl who knew little but wanted to learn.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 18/06/2026
I'll be honest - I had to look up flucloxacillin and cloxacillin to figure out if they were IV or PO because I've only ever used oxacillin and nafcillin. This is a great paper, though, and yet another opportunity to talk about the inoculum (Eagle) effect!
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 07/06/2026
There's a talk I wish I had seen! She (and her husband!) are the epitome of turning something bad into something good.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 18/05/2026
This deserves a meme from their childhood
static.klipy.com
Fred Armisen: Right To Jail
Alt: Fred Armisen: Right To Jail
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 26/04/2026
I was at PAS yesterday but left early - folks were vocally upset that the only Trans-related session was from a SPLC hate group. The chair writes one-sided anti-Trans position papers. I'm surprised they would be so one sided (and a lot more thoughts than can be expressed in this limited context)
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 24/04/2026
I know at least some US arms of studies for outpatient Paxlovid struggled to recruit as well. These types of studies are difficult, especially as reliable testing fell off after 2022 or so.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 24/04/2026
Agreed both studies failed to meet initial recruitment goals based on their power calculations. The people they recruited, though, were also problematic. This was a very homogeneous, relatively affluent, highly vaccinated, and healthy cohort based on Table 1. Not the patients most likely to benefit.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 12/04/2026
I have a recipe for a pudding that says to "bake in a medium oven" which, according to my mom after trial and error, is 350 degrees'
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 29/03/2026
This data is important and this is a question we need to answer for phage therapy. We already know the answer for most small molecule antibiotics - they are less active in biofilm and other infectious milieus that have lower replication rates. It's a tough problem! #phagesky
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 27/03/2026
I still have a copy of one of the original decks that was free to print (I hope) back in 2020-ish - we keep them in our resident room. Looks like I may have to upgrade :)
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 26/03/2026
@empiricgame.bsky.social I just saw this! You've made the big time!!
picture of great card game called "Empiric! Sanford Guide Edition", a game about learning antibiotics and their uses
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 07/03/2026
I learned a decent amount about nutrition in med school (10 yrs ago, and with subsequent education throughout residency), but my school isn't on the list either.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 07/03/2026
This is absolutely wild. They are saying that stewardship harms patient care - "inappropriate balance of stewardship over patient-oriented perspectives" Also "lack of appreciation of uncertainty in the etiologies of pneumonia" - as if we don't hem and haw about these things all day long.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 15/01/2026
I played a small role helping set up local protocols for MTb evaluations - happy to see this work continuing to grow! Kutscher, et al, put in significant work - for those who've worked in a BSL3, the work required to complete an animal study, especially the length/complexity for MTb, is Herculean.
journals.asm.org
Repeated pulmonary dosing of β-glucan-chitosan-PLGA nanoparticles controls Mycobacterium tuberculosis in mice | Antimicrobial Agents and Chemotherapy
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading global health threat. In 2023, TB was responsible for an estimated 1.25 million deaths and once again became the single...
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 13/01/2026
This is something to aspire to! #phagesky
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 21/12/2025
We just posted a new preprint describing an anti-MRSA phage targeting the terminal β-GlcNAc on wall teichoic acid. The host becomes phage resistant, but methicillin susceptibility is the consequence in some pathways; cotreatment with methicillin is synergistic at achievable MICs. #phagesky #IDsky
biorxiv.org
Lytic anti-Staphylococcus aureus phage M963 resensitizes its host to methicillin by a tarS-dependent mechanism
Bacteriophage M963 targeting a clinical strain of methicillin-resistant Staphylococcus aureus (MRSA) was isolated from wastewater. Purification was optimized and the phage was subsequently characteriz...
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NEJM.org @nejm.org · 02/12/2025
Our latest video in our partnership with @glaucomflecken.bsky.social summarizes a new trial investigating the mass administration of ivermectin for reducing malaria transmission. Read the full results of the BOHEMIA trial for free: nej.md/DrG31
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 22/11/2025
Happy someone did the math! I've run into this numerous times and have had lots of theories but no time/energy/math skills to follow through - there's a sweet spot at an MOI around 10^-3 to -5 where resistance may still occur, but above/below that the bacteria win faster in a simple system.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 22/11/2025
I started studying phages just over 4 years ago. The project that started it all is finally published. We isolated 6 closely related anti-Acinetobacter phages and showed that they are not capsule-specific and can reduce bacterial load in a rat model. More work still to come on this! #phagesky #IDsky
cell.com
A bacteriophage genus infects carbapenem resistant Acinetobacter baumannii via a non-capsular receptor and provides protection in vivo
Microbiology; Virology
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BK. Titanji @boghuma.bsky.social · 20/11/2025
If there was any doubt at all that the CDC is fully destroyed, this page on autism and vaccines on its website confirms it. It's now just another vessel of dangerous health misinformation. I have no words. This is beyond sad.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 13/11/2025
This is a great preprint - I can't wait to see the polished product!
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 06/11/2025
@puzzlebetter.bsky.social www.youtube.com/shorts/Q8UGF...
youtube.com
Infectious Disease Doctor Goes To A Soccer Game
YouTube video by Dr. Glaucomflecken
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 06/11/2025
Hoping this is the start of something great - Lassa is a scourge
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Ed Rybicki 🇿🇲🇿🇦🇬🇧🍷🚀 @edrybicki.bsky.social · 30/10/2025
@isv-news.bsky.social #ISV2025 Alec Freyn, Moderna presenting ISV Paper of the Year 2025 - quadrivalent mRNA vaccine against a broad spectrum of orthopoxviruses.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 24/10/2025
It's interesting (in a bad way) that these bigger LLMs seem so off with their advice in a lot of different fields and so prone to hallucinations. Meanwhile, I know folks who use OpenEvidence regularly and haven't had similar issues. I wonder if the big ones just absorb too much questionable material
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 23/10/2025
media.tenor.com
a drawing of a dinosaur with the words " and i don 't like it " above it
ALT: a drawing of a dinosaur with the words " and i don 't like it " above it
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 23/10/2025
This one hurts. yikes
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 21/10/2025
Glad to see someone is still trying this drug for the US! The FDA declined to approve a few years ago based on (if I remember right) some issues about prespecified endpoints on an otherwise solid trial. I have concerns about overuse, but this could keep people out of hospital and off OPAT. #IDSky
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BK. Titanji @boghuma.bsky.social · 03/10/2025
Speaking for all physicians and healthcare providers here. When we see patients in need of care especially in an emergency room we do not leave them for dead. We do not care about their immigration status, we treat them because that is what we took an oath to do and is also basic human decency.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 26/09/2025
media.tenor.com
a man in a suit and tie says no respect
Alt: a man in a suit and tie says no respect
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 09/09/2025
Other groups use it successfully, so I know it's a me problem. To be fair, up until a few weeks ago I couldn't even figure out how to download something from GitHub (a dangerous admission, I know).
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 09/09/2025
I can muddle my way through installing Python and even figured out how to install Bacphlip, but it seems to run on an old version of python, and even if I get that going, I can't get the command line to run the script on the genome of interest. I'm sure it's something silly.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 09/09/2025
I'm afraid you're not open to messaging. My overall bioinformatics needs are high (someday, over the rainbow , I'll have funding to hire a full time bioinformatics specialist / geneticist), but the current need is narrow. I am just trying to figure out how to make Bacphlip work.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 06/09/2025
There are lots of things I wish I knew - today I wish I knew how to use Python (or had the time to learn!). Right after that is my wish that someone would put Bacphlip on the phage.galaxy.eu UI so old fogies like me who learned chemistry instead of programming can use it 😭 #phage
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 10/08/2025
great thread!!
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BK. Titanji @boghuma.bsky.social · 09/08/2025
"First do not harm" is not a suggestion it is a core feature of the job. If you can't check your biases at the door when you provide healthcare, find another job. Calling ICE on a patient is some disgusting behavior. www.washingtonpost.com/health/2025/...
washingtonpost.com
Patient seeking care at NIH hospital detained by ICE
NIH officials called immigration authorities after scrutinizing the patient’s identification presented to security at the National Institutes of Health Clinical Center.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 05/08/2025
Raw milk in the US has significant safety issues, no matter what some folks say. #IDSky
apnews.com
Raw milk sickens 21 people in Florida including 6 children
Public health officials in Florida are reporting 21 cases of campylobacter and E. coli infections linked to drinking raw milk, all from the same farm.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 19/07/2025
A must read
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 17/07/2025
This is a nice report - goes along with anecdotal data as well as extrapolation from dalbavancin. What is wild, though, is that 9 of 27 patients in this study had PSSA. 33%!! I think I saw a PSSA isolate once... #IDSky
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Reposted by Patrick Kenney, MD MS
Jake Scott, MD @jakescottmd.bsky.social · 13/06/2025
RFK Jr. spouted dangerous vaccine falsehoods on national TV. As a parent and infectious diseases doctor, I couldn't stay silent. Here's what the data actually shows. 🧵
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Dimitri Drekonja, MD, MS @dimitridrekonja.bsky.social · 10/06/2025
New moment of “WTF”: -pt with rare infection (so rare will leave unnamed, as could reveal identity) -nl times: reach out to CDC for testing -now: “they confirmed they are not currently accepting specimens for serology…they suggested we could reach out to Canada National Reference Center” 😳😳😳
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 10/06/2025
Short but accurate - firing the ACIP experts hurts everyone. #IDSky www.idsociety.org/news--public...
idsociety.org
Statement on the Advisory Committee on Immunization Practices
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 01/06/2025
The ongoing tragedy of American withdrawal from aid programs: www.npr.org/sections/goa...
npr.org
Marco Rubio said no one has died due to U.S. aid cuts. This mom disagrees
Mariam Mohammed says her younger son died when she could not get treatment for him at a U.S.-funded clinic that had temporarily closed. Researchers say there are many thousands of cases like his.
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 17/05/2025
I love the name phage to sharks. Awesome packaging
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 17/05/2025
Another Recovery paper. I think this one is a victim to earlier success. Study numbers are low, most had vaccine, and most had other antivirals. I don't think you can make any conclusions here. My 2¢ - future studies need to focus on soft outcomes (hospital, ED, etc) or special populations. #IDSky
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 17/05/2025
Haha so true. At VA hospitals (US) there is no ability to change font, at least where I was, so no italicization. It hurt my soul.
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Molly Franke @mollyfranke.bsky.social · 15/05/2025
All 4 of my NIH research grants are terminated. These were grants on MDR-TB treatment & strategies for supporting adolescents living w/ HIV. This is a massive waste of resources. I am heartbroken for my Harvard team, my partners in Peru, the next generation of scientists & our country. Shame.
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CIDRAP @cidrap.bsky.social · 01/05/2025
Inhaled bacteriophage therapy shows promise in cystic fibrosis patients In a small study, CF patients treated with the therapy saw a reduction in multidrug-resistant lung bacteria and improved lung function. www.cidrap.umn.edu/a...
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Patrick Kenney, MD MS @patrickkenney.bsky.social · 26/04/2025
Amazing you got to hear it first hand. It is a really intriguing model that has some real possible benefits.
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