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Paris Biofoundry

@parisbiofoundry.bsky.social
115 followers 79 following 34 posts

The Paris Biofoundry is a collaborative platform uniting leading institutions in the Île-de-France region. It focuses on engineering biological systems for health, environmental, and industrial applications. parisbiofoundry.org

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Paris Biofoundry @parisbiofoundry.bsky.social · 21/05/2026
📅 Save the date ! The Paris Biofoundry is proud to host the Global Biofoundry Alliance (GBA) Summit 2026. 🗓 Nov 16–18, 2026 📍 Sorbonne Université, Paris 🔗 Register now: premc.org/gba2026/ #GBA2026 #ParisBiofoundry #SyntheticBiology #Biofoundry #DBTL @slemaire75.bsky.social
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Paris Biofoundry @parisbiofoundry.bsky.social · 09/12/2025
Great visit today at the Paris Biofoundry! 🇫🇷🤝🇰🇷 We welcomed a delegation from the Korean Biofoundry and the Ministry of Science & ICT to exchange on automation, DBTL workflows, and future collaboration opportunities. Exciting prospects ahead! 🚀 #Biofoundry #SynBio
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Paris Biofoundry @parisbiofoundry.bsky.social · 01/12/2025
📣Call for proposals now open! The Paris Biofoundry launches a new program to support innovative projects aligned with our 4 axes: High-throughput DNA assembly, in-vivo engineering & phenotyping, cell-free engineering, bioprocess scale-up Details here👉 parisbiofoundry.org/2025/12/01/t...
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Paris Biofoundry @parisbiofoundry.bsky.social · 27/11/2025
We’re live at #ForumBiotechno Paris 2025! The Paris Biofoundry joins the community of young scientists & innovators shaping the future of #biotech. 🎤 Catch Victor Kreis, president of Forum Biotechno, presenting how we accelerate research through #automation & #SyntheticBiology! #Innovation
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Paris Biofoundry @parisbiofoundry.bsky.social · 26/11/2025
💬 We are live from the #InnovationDay2025 by @iledefrance.bsky.social! 🎙️ Ariel Lindner opened the day with a talk on bioethics & bioengineering 🤖 Ramiz Khaled & Mostafa Mahdy presented automated workflows from the #ParisBiofoundry A full day of inspiring exchanges ahead! @SLemaire75.bsky.social
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Paris Biofoundry @parisbiofoundry.bsky.social · 25/11/2025
Tomorrow, the #DIMBioConvS #InnovationDay 2025 begins! We’re proud to see our team take part: 🎙️ Ariel Lindner (CSO #ParisBiofoundry) 🤖 Ramiz Khaled & Mostafa Mahdy (@inrae-france.bsky.social) Ready to share how we advances #automation & #bioethics in #SyntheticBiology. @iledefrance.bsky.social
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Paris Biofoundry @parisbiofoundry.bsky.social · 19/11/2025
What do we do ?🔬 The Paris Biofoundry accelerates synthetic biology through automation and AI-driven workflows. From DNA assembly to cell-free production and scale-up, we help researchers design, build & test biological systems at scale. #ParisBiofoundry #SyntheticBiology @slemaire.bsky.social
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Paris Biofoundry @parisbiofoundry.bsky.social · 17/11/2025
📅Save the date! The #DIMBioConvS #InnovationDay “Joining Forces” happens Nov 26 at the Conseil Régional d'@iledefrance! 💬 Featuring talks by 🔹 Ariel Lindner (CSO, Paris Biofoundry) 🔹 Ramiz Khaled & Mostafa Mahdy (@INRAE_MICALIS) #ParisBiofoundry #SyntheticBiology
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Paris Biofoundry @parisbiofoundry.bsky.social · 12/11/2025
What is a biofoundry? 🔬 A place where robotics, automation & biology meet — enabling high-speed design, build & testing of biological systems. Transforming research into innovation. 🧬 Learn more: parisbiofoundry.org #Biofoundry #SyntheticBiology #ParisBiofoundry @slemaire75.bsky.social
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Paris Biofoundry @parisbiofoundry.bsky.social · 07/11/2025
The Paris Biofoundry joins Forum BioTechno Paris 2025! A key event bringing together young scientists, researchers & industry leaders shaping the future of #biotech. Don’t miss Victor Kreis presenting the Paris Biofoundry at the Flash Talk session! 📅Nov 27 |📍Epitech Paris
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Paris Biofoundry @parisbiofoundry.bsky.social · 31/10/2025
🧬Exciting discussions on Day 2 of #SB8 at #IGEM2025! Co-organized by Ariel Lindner, Drew Endy and Matthey Chang, today's focus was bioengineering workflows, biosecurity & global collaboration. Proud to see the Paris Biofoundry contribute to this worldwide dialogue! @parisbiofoundry.bsky.social
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Paris Biofoundry @parisbiofoundry.bsky.social · 30/10/2025
🌿 Today at #iGEM2025, Professor @slemaire75.bsky.social, Director of the Paris Biofoundry, shared his vision on how synthetic biology and innovation can drive a more sustainable future. Proud to see the Paris Biofoundry represented once again at iGEM! 💡 #SyntheticBiology #Innovation
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Paris Biofoundry @parisbiofoundry.bsky.social · 03/10/2025
🌏 Honored to host a New Zealand 🇳🇿 delegation at Sorbonne Université & the Paris Biofoundry — presenting our platform and exploring how biofoundries can support their national ambitions. #ParisBiofoundry #SyntheticBiology #Collaboration @sorbonne-universite.fr @slemaire75.bsky.social
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Paris Biofoundry @parisbiofoundry.bsky.social · 24/09/2025
🤝 The Paris Biofoundry spent 2 days with Concordia Genome Foundry 🇨🇦 — sharing best practices, discussing #robotics & #SyntheticBiology, and strengthening ties between #biofoundries worldwide. #ParisBiofoundry #Collaboration @slemaire75.bsky.social @sorbonne-universite.fr
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Paris Biofoundry @parisbiofoundry.bsky.social · 20/09/2025
🎤 At #GBA2025, @slemaire75.bsky.social introduced the distributed sites and latest progress of the Paris Biofoundry and announced that Paris will host the GBA Summit 2026! 🇫🇷 Excited to welcome the global biofoundry community next year! #ParisBiofoundry #GBA2026 #GBA #Biofoundries
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Paris Biofoundry @parisbiofoundry.bsky.social · 18/09/2025
🌍 The Paris Biofoundry joined the Global Biofoundry Alliance Summit 2025 at Illinois University (Sept 18–19)! 🇺🇸 A unique moment to connect with biofoundries worldwide & shape the future of synthetic biology together. #ParisBiofoundry #GBA2025 #SyntheticBiology #Innovation @slemaire75.bsky.social
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Paris Biofoundry @parisbiofoundry.bsky.social · 25/08/2025
🌱 #Chlamy2025 has started at @uni-muenster.de! The Paris Biofoundry is proud to join the global #Chlamydomonas community — as the only #biofoundry worldwide working on this #algae. Kudos to Julien Henri & Marta Bertolini (@sorbonne-universite.fr) for today’s inspiring talks 👏 #SyntheticBiology
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Paris Biofoundry @parisbiofoundry.bsky.social · 30/05/2025
🎉 GateX is now officially inaugurated at @genopole.bsky.social! A founding site of the Paris Biofoundry, #GateX focuses on scaling up bioproduction—bridging the gap between lab research and industrial applications. 🔬 Another milestone for open, integrated synthetic biology. #ScaleUp
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Paris Biofoundry @parisbiofoundry.bsky.social · 26/05/2025
📢 Only 5 days left until The SC-DNA 2025 registration deadline! Register now to attend the Storage & Computing with DNA 2025 conference (June 19-21, @sorbonne-universite.fr)! 📷 premc.org/storage-comp... #DNADataStorage #ComputingWithDNA #SCDNA2025
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Paris Biofoundry @parisbiofoundry.bsky.social · 15/05/2025
🌍It was a great honor to host #BriardoLlorente from the #AustralianGenomeFoundry at the #ParisBiofoundry! We exchanged insights, experiences and collaboration opportunities, and toured the Sorbonne Foundry to showcase our cutting-edge facilities. @arccoesb.bsky.social @parisbiofoundry.bsky.social
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Paris Biofoundry @parisbiofoundry.bsky.social · 05/05/2025
🚀 The #DNAfoundry at @parisbiofoundry.bsky.social is now fully assembled! A new hub for #highthroughput DNA design, #assembly & #sequencing, accelerating #SyntheticBiology research.🔬✨ @cnrs.fr @sorbonne-universite.fr @genopole.bsky.social @institutcurie.bsky.social @inrae-france.bsky.social
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Paris Biofoundry @parisbiofoundry.bsky.social · 23/04/2025
📢 The SC-DNA 2025 registration deadline is extended to May 31st! Register now to attend the Storage & Computing with DNA 2025 conference (June 19-21, @sorbonne-universite.fr)! 📷 🔗 premc.org/storage-comp... #DNADataStorage #ComputingWithDNA #SCDNA2025
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Paris Biofoundry @parisbiofoundry.bsky.social · 17/04/2025
📢 SC-DNA 2025 Program Confirmed! The program of the Storage & Computing with DNA 2025 conference (June 19-21, @sorbonne-universite.fr , Paris.) is now available! 🧬💾 📅 Find more about the event here 🔗 sc-dna2025.exordo.com/programme/se... #SCDNA2025 #DNADataStorage #ComputingWithDNA
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Paris Biofoundry @parisbiofoundry.bsky.social · 07/04/2025
📢 Confirmed Speakers Announced! The #SCDNA2025 abstract submission is now closed — and our speaker lineup is officially set! 🧬💾 Get ready to hear from world-class international experts shaping the future of DNA storage and DNA computing. 📅 Register by April 21st: 🔗 premc.org/storage-comp...
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Paris Biofoundry @parisbiofoundry.bsky.social · 03/03/2025
🚨 Deadline Extension for Storage and Computing with DNA 2025 🚨 🔹 New abstract submission deadline: March 21, 2025 🔹 New registration deadline: April 21, 2025 premc.org/storage-comp... @dnadatastorage.bsky.social @biomemory.com @sorbonne-universite.fr @slemaire75.bsky.social @pcrozet.bsky.social
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Di Jiang @dijiang319.bsky.social · 01/02/2025
@science.org Genome recombination on demand | Science www.science.org/doi/10.1126/... a Perspective by @seczmarta.bsky.social Lars Steinmetz @stanford.edu on two studies bit.ly/4hzFRMg + bit.ly/4jyT4Hf that generate large genome rearrangements in mammalian cells @ unprecedented scale #synbio #genome
science.org
Genome recombination on demand
Large genome rearrangements in mammalian cells can be generated at scale
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Gene Chong @chongg.bsky.social · 07/02/2025
A binary population of biomimetic membraneless organelles delivers molecular messages with controllable feedback #synbio #ChemBio www.nature.com/articles/s41...
nature.com
Programming biological communication between distinct membraneless compartments - Nature Chemical Biology
A biosynthetic binary population of membraneless compartments is engineered to mimic membraneless organelles and is capable of delivering molecular messages with controllable feedback under cellular e...
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Pash Bio @pashbio.substack.com · 20/02/2025
Ever wondered just how much stuff that makes life good relies on #fossil fuels? 🏭 Have a gander at my first essay on #engbio. The main take: engbio is the most promising option to phase out oil-derived materials. 🦠🌍 open.substack.com/pub/pashbio/... #biotech #synbio #bioeconomy #sustainability
open.substack.com
Wait, it's all oil?
Always has been - but there's a natural way out
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Niko McCarty @nikomccarty.bsky.social · 16/02/2025
How to "program" living cells.🧫 In 2000, physicists (incl. Michael Elowitz) made bacteria blink on-and-off every 150 minutes. Their experiment, which blended mathematics and wet-lab methods, launched the field of synthetic biology. Learn how they did it in my first interactive story!
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OECD Innovation @oecdinnovation.bsky.social · 24/02/2025
#SyntheticBiology can transform industries and health, boost economies, and tackle societal challenges. Our new paper synthesises findings of over 60 experts who met regularly in 2023-24 to explore opportunities, challenges, and policy needs. 📄 Read here: oe.cd/5W1 #synbio #biotech #emergingtech
Synthetic biology in focus: Policy issues and opportunities in engineering life
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Nature Portfolio @natureportfolio.nature.com · 23/02/2025
Synthetic biologists discuss with Nature why it’s so hard to write a genome. “We underestimated how complex biology is.” 🧪 🧬
go.nature.com
Why is it so hard to rewrite a genome?
Synthetic biologists have the know-how and ambition to retool whole genomes. But the hidden complexity of biological systems continues to surprise them.
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Marc Somssich @somssich.bsky.social · 24/02/2025
📜 The Marchantia polymorpha pangenome reveals ancient mechanisms of plant adaptation to the environment 🧑‍🔬 @chloe-beaulieu.bsky.social, Cyril Libourel, @maximebonhomme.bsky.social, @pierremarcdelaux.bsky.social, et al. 📔 @natureplants.bsky.social 🔗 www.nature.com/articles/s41... #️⃣ #PlantEvolution
nature.com
The Marchantia polymorpha pangenome reveals ancient mechanisms of plant adaptation to the environment - Nature Genetics
Pangenome analyses of 133 wild accessions of the model bryophyte Marchantia polymorpha identify adaptive features and provide insights into the mechanisms of plant adaptation to the terrestrial enviro...
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Matteo Pivato @matteopivato.bsky.social · 24/01/2025
Wandering what happens to Chlamydomonas chloroplast and cytosolic Ca2+ dynamics in response to different abiotic stresses? Our latest work about that is out now! 🦠🔬 A big thank to all the people involved @labcosta.bsky.social, Glen Wheeler and Matteo Ballottari.
onlinelibrary.wiley.com
Abiotic Stress‐Induced Chloroplast and Cytosolic Ca2+ Dynamics in the Green Alga Chlamydomonas reinhardtii
Ca2+ signalling has a key role in the perception of environmental stimuli and cellular responses to stresses. Here we show that Ca2+ transients in Chlamydomonas are differently triggered by abiotic s...
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Stéphane Lemaire @slemaire75.bsky.social · 08/02/2025
Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus | Science www.science.org/doi/10.1126/...
science.org
Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus
In eukaryotes, DNA-associated protein complexes coevolve with genomic sequences to orchestrate chromatin folding. We investigate the relationship between DNA sequence and the spontaneous loading and a...
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Sara Trujillo @sara-truji.bsky.social · 05/02/2025
Yesterday, we had the pleasure at @leibnizinm.bsky.social to hear Dr Lemaire from the @parisbiofoundry.bsky.social on how DNA can be used for data storage 🧪 and the amazing capabilities of the biofoindry! Such a joy 🙂 Here my sketchnotes✏️
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Paris Biofoundry @parisbiofoundry.bsky.social · 05/02/2025
www.nature.com/articles/s41...
nature.com
Design and regulation of engineered bacteria for environmental release - Nature Microbiology
Chemla et al. review the release of bacteria into the environment and propose engineering strategies to help improve performance and reduce risk.
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Filippo Caschera @stjle.bsky.social · 11/01/2025
Cell-Free PURE System: Evolution and Achievements www.sciencedirect.com/science/arti... #CellFree #CFPS #SynBio
sciencedirect.com
Cell-Free PURE System: Evolution and Achievements
The cell-free protein synthesis (CFPS) system, as a technical core of synthetic biology, can simulate the transcription and translation process in an …
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Paris Biofoundry @parisbiofoundry.bsky.social · 02/02/2025
Randomizing the human genome by engineering recombination between repeat elements | Science www.science.org/doi/10.1126/...
science.org
Randomizing the human genome by engineering recombination between repeat elements
We lack tools to edit DNA sequences at scales necessary to study 99% of the human genome that is noncoding. To address this gap, we applied CRISPR prime editing to insert recombination handles into re...
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Olivier Borkowski @oborkowski.bsky.social · 02/02/2025
Incoherent feedback from coupled amino acids and ribosome pools generates damped oscillations in growing E. coli doi.org/10.1101/2023...
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Olivier Borkowski @oborkowski.bsky.social · 02/02/2025
Cell-Free Synthesis System: An Accessible Platform from Biosensing to Biomanufacturing doi.org/10.1016/j.mi...
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Twist Bioscience @twistbioscience.com · 24/01/2025
Self-driving laboratories, advanced immunotherapies and five more technologies to watch in 2025! www.nature.com/articles/d41...
nature.com
Self-driving laboratories, advanced immunotherapies and five more technologies to watch in 2025
Sustainability and artificial intelligence dominate our seventh annual round-up of exciting innovations.
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The Plant Cell @theplantcell.bsky.social · 24/01/2025
Synthetic photorespiratory bypass improves rice productivity by enhancing photosynthesis and nitrogen uptake (Guoxin Chen, Yanni Li, Kaining Jin, Jiabei Gao, Suting Wu, Xuean Cui, Chuanzao Mao, Xinyou Yin, Tiegang Lu, Zhiguo Zhang) doi.org/10.1093/plcell/koaf015 #PlantScience
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Olivier Borkowski @oborkowski.bsky.social · 26/01/2025
Automated adjustment of metabolic niches enables the control of natural and engineered microbial co-cultures doi.org/10.1016/j.ti...
doi.org
Redirecting
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Ben Long @botbml.bsky.social · 26/01/2025
Rubisco is slow across the tree of life doi.org/10.1101/2025...
doi.org
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Olivier Borkowski @oborkowski.bsky.social · 27/01/2025
Cell-free protein synthesis as a method to rapidly screen machine learning-directed protease variants doi.org/10.1101/2025...
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Ben Long @botbml.bsky.social · 27/01/2025
A collection of amazing Rubisco papers and preprints this week. Here's another! www.biorxiv.org/content/10.1...
biorxiv.org
A cyanobacterial screening platform for Rubisco mutant variants
Rubisco is the main entry point of inorganic carbon into the biosphere and a central player in the global carbon system. Its relatively low catalytic constant as well as its tendency to also accept O2...
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Paris Biofoundry @parisbiofoundry.bsky.social · 29/01/2025
📢 Big news at the Paris Biofoundry! We’ve welcomed the Echo 650T Series Acoustic Liquid Handler from #BeckmanCoulter . With contact-free acoustic transfers down to 2.5 nL, this game-changing tool enhances assay miniaturization and boosts efficiency for #DNAassembly, #DrugDiscovery and more!
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Paris Biofoundry @parisbiofoundry.bsky.social · 22/01/2025
📰 Excited to see the @parisbiofoundry.bsky.social featured in @lemonde.fr! The article highlights our work tackling antibiotic resistance, led by @vincent-libis.bsky.social. 🔬 Discover how we’re using synthetic biology to uncover new antibiotics from soil microbes: www.lemonde.fr/sciences/art...
lemonde.fr
La recherche française s’organise face aux bactéries résistantes aux antibiotiques
Menace sanitaire croissante considérée comme une priorité de santé, les infections dues à des bactéries résistantes aux antibiotiques pourraient tuer 1,28 million de personnes dans le monde en 2030. F...
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Paris Biofoundry @parisbiofoundry.bsky.social · 15/01/2025
📢 Join us for "Storage and Computing with DNA 2025" at @sorbonne-universite.fr from June 19-21, 2025! Connect with academic, industry and startup leaders in DNA data storage and computing. 🧬 Details 👉 premc.org/storage-comp... #DNA #SCDNA2025 #DNADatastorage #ComputingWithDNA #Conference2025
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Paris Biofoundry @parisbiofoundry.bsky.social · 09/01/2025
📢 We’re hiring at the Paris Biofoundry! Join us as a Communication Manager and help shape the future of synthetic biology and bioengineering. 📍 Location: Sorbonne University, Paris 📅 Start: March-April 2025 Interested? Apply now! 🔗 www.parisbiofoundry.org #Joboffer #BioTech #ParisBiofoundry
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