Orthopedic infection is usually managed with surgery and prolonged systemic antibiotic therapy. Whether local antibiotics delivered by a product implanted at the infection site during surgery can r...

mRNA vaccines represent a transformative advance in vaccinology, combining rapid development timelines, scalable manufacturing, and strong immunogenicity with a favourable safety profile. Global deplo...

The Infectious Diseases Society of America and Society for Healthcare Epidemiology of America formally defined antimicrobial stewardship in 1997, recognizi

La Seimc confía en que la especialidad de Enfermedades Infecciosas quede aprobada este otoño y pueda incorporarse por primera vez a la oferta MIR de 2028.

Prevalence surveys in U.S. hospitals showed that on any given day, 1 of 25 patients had a health care–associated infection in 2011, as compared with 1 of 31 patients in 2015. We repeated the survey...

Bundibugyo virus is a relatively rare orthoebolavirus that has caused only two previously recognized disease outbreaks but remains capable of producing severe epidemic disease with substantial mort...

Andes virus (ANDV) is the sole orthohantavirus with documented human-to-human transmission. We summarize the epidemiology and clinical features of ANDV infection and review best practices in clinic...

Although the prespecified non-inferiority criterion for benzylpenicillin was not met, the probability of benzylpenicillin being non-inferior for mortality, along with a reduction in risk of AKI, indic...

Staphylococcus aureus bacteremia is associated with high mortality. Whether cefazolin or an antistaphylococcal penicillin should be preferred for the treatment of methicillin-susceptible S. aureus ...

Treatment with bepirovirsen, an antisense oligonucleotide targeting hepatitis B virus (HBV) transcripts, has the potential to result in a functional cure, defined by at least 24 weeks of a sustaine...

The current treatment of chronic hepatitis B infection includes nucleoside or nucleotide analogue (NA) therapy and pegylated interferon. Both of these treatments are effective in suppressing hepati...

De los 78,8 especialistas por millón de habitantes en Suecia a la ausencia de un título oficial en España; el mapa europeo de la infectología revela una disparidad que pone en jaque la respuesta ante ...

GSK’s “bepi” performs better than expected in efficacy trials, but its global impact is likely limited

On May 2, hantavirus infection was diagnosed in a patient who had been on a cruise ship. Subsequent evaluation revealed multiple cases of Andes hantavirus infection on the ship. To date, three asso...

Public-health researcher James Baguma has studied the interactions between bats, which can carry the virus, and people in the region near the latest epidemic.

Lower urinary tract infections (UTIs; cystitis) are very frequent: at least 50% of women will have at least one episode during their lifetime, and many have more than one episode,1 making it a frequen...

Nitrofurantoin was the most effective treatment and single-dose fosfomycin the least effective treatment for UTIs. Adverse events were mild. The role of fosfomycin as a first-line antibiotic for uncom...

This editorial contextualizes a study of sequencing of pleural fluid and plasma for tuberculous pleuritis.

The laboratory diagnosis of tuberculous pleuritis (TBP) is hindered by the paucibacillary nature of Mycobacterium tuberculosis in the pleural space, resulting in low sensitivity of microbiological ...

Malaria control and elimination is threatened by the spread of insecticide resistance and behavioral adaptation of vectors. Whether mass administration of ivermectin, a broad-spectrum antiparasitic...

After decades of stagnation, a renewed push in tuberculosis research is expanding the drug and vaccine pipeline to bring one of humanity’s oldest and deadliest infectious diseases under control.

Why aren’t we using it?

El actor y director se visibiliza como un referente seropositivo en España, donde ningún personaje tan popular había dado ese paso: “Deseo que esto pueda ayudar a más gente”

Barbara W Trautner, Nicolás W Cortés-Penfield, Kalpana Gupta, Elizabeth B Hirsch, Molly Horstman, Gregory J Moran, Richard Colgan, John C O’Horo, Muhammad

This JAMA Insights discusses the epidemiology, diagnosis, and treatment of recurrent Clostridioides difficile infections.

The Infectious Diseases Society of America (IDSA) did not endorse updated community-acquired pneumonia guidelines because they recommend antibiotics for pa

The WikiGuidelines for Pyogenic Osteomyelitis was first published in May 2022.1 Herein we summarize updates as of October 2025, detailed and highlighted in the complete revised guideline (Supplement 1...

This systematic review and meta-analysis evaluates the evidence supporting the current guidelines antibiotic prophylaxis use in patients with cirrhosis and upper gastrointestinal bleeding.

This systematic review and meta-analysis evaluates the evidence supporting the current guidelines antibiotic prophylaxis use in patients with cirrhosis and upper gastrointestinal bleeding.

The WikiGuidelines for Pyogenic Osteomyelitis was first published in May 2022.1 Herein we summarize updates as of October 2025, detailed and highlighted in the complete revised guideline (Supplement 1...

Background: The benefit–risk profile of systemic corticosteroids in non–COVID-19 pneumonia and acute respiratory distress syndrome (ARDS) remains debated. Purpose: To assess corticosteroid effects on ...

Lenacapavir is a twice-yearly injectable drug produced by Gilead Sciences that is aimed at preventing HIV infection. In 2024, the findings of the PURPOSE 1 and PURPOSE 2 trials testing lenacapavir for...

Understanding the impact of antibiotic use on future resistant infections is essential for appropriate antibiotic therapy. Our objective was to assess the effect of exposure to commonly used antibioti...

This Viewpoint discusses the disadvantages of direct-to-consumer home tests for chlamydia and gonorrhea in terms of the goals of public health authorities related to the management and control of sexu...

This study investigated whether consuming caffeinated coffee affects the risk of recurrent atrial fibrillation episodes compared with abstaining from coffee and caffeine after successful cardioversion...