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OmicsPred

@omicspred.bsky.social
63 followers 6 following 9 posts

A resource to enhance the accessibility and usability of genetic scores for multi-omic traits and their phenotypic associations www.omicspred.org

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Reposted by OmicsPred
Sam Lambert @iamslambert.bsky.social · 20/05/2026
This is a collaborative effort with colleagues @ UChicago (@hakyim.bsky.social) and our Cambridge group (@mikeinouye.bsky.social @cfoguet.bsky.social @laurentgil33.bsky.social @yuxu.bsky.social) + many more! Thanks to authors for making their data open, add yours here: www.omicspred.org/submit!
omicspred.org
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Reposted by OmicsPred
Sam Lambert @iamslambert.bsky.social · 20/05/2026
@omicspred.bsky.social centralises imputation models from multiple resources (PredictDB, Zenodo, INTERVAL/UKB-trained scores) and multiple omics layers (transcriptomics, metabolomics, proteomics) to make analyses easier and more comprehensive, e.x. this multi-ancestry multi-omics MVP PheWAS!
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Reposted by OmicsPred
Sam Lambert @iamslambert.bsky.social · 20/05/2026
Interested in applying multi-omics imputation or TWAS/PWAS approaches to your data? Frustrated by the models being spread across multiple resources? Enter OmicsPred: a centralised resource for genetic prediction of multi-omic traits! 🔗 : www.omicspred.org 📃 : www.medrxiv.org/content/10.6...
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Reposted by OmicsPred
Mike Inouye @mikeinouye.bsky.social · 20/05/2026
OmicsPred (www.omicspred.org) has been almost completely overhauled with new front-end, back-end, features, pheWAS and multi-omic scores (>3 million and counting).
medrxiv.org
OmicsPred as a centralised resource for genetic prediction of multi-omic traits
Genetic prediction of multi-omic data has emerged as a cost-effective alternative to direct omics profiling, particularly useful for identifying molecular features associated with disease susceptibili...
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Reposted by OmicsPred
Mike Inouye @mikeinouye.bsky.social · 20/05/2026
Together with Haky Im and colleagues at the University of Chicago, we brought together two leading resources for transcriptome/proteome/metabolome-wide association studies: OmicsPred and PredictDB. www.medrxiv.org/content/10.6... www.omicspred.org
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Reposted by OmicsPred
Mike Inouye @mikeinouye.bsky.social · 20/05/2026
Wonderful to see the new integrated OmicsPred resource now preprinted at medrxiv: "OmicsPred as a centralised resource for genetic prediction of multi-omic traits" www.medrxiv.org/content/10.6... OmicsPred: www.omicspred.org
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OmicsPred @omicspred.bsky.social · 16/06/2025
We're working closely with our PredictDB colleagues to bring you an integrated resource for multi-omic predictors We're happy to announce that PrediXcan GTExV8 expression predictors are now annotated and openly available via OmicsPred! www.omicspred.org More info www.omicspred.org/publication/...
omicspred.org
OmicsPred is an atlas of genetic scores for prediction of multi-omics data.
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OmicsPred @omicspred.bsky.social · 06/02/2025
OmicsPred is developed by @laurentgil33.bsky.social @yuxu.bsky.social @iamslambert.bsky.social @mikeinouye.bsky.social with support from @uniofcam.bsky.social, HDRUK, @ebi.embl.org and the Baker Institute. Many thanks also to @hakyim.bsky.social, Ruidong Xiang, many others! (8/N)
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OmicsPred @omicspred.bsky.social · 06/02/2025
We encourage users to contribute newly developed multi-omic genetic scores, fresh evaluations of existing scores, and new association results from additional cohorts. Sharing helps the community maximize utility and accessibility of these scores! Submit your scores: forms.gle/KLZGbvurrftF... (7/N)
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OmicsPred @omicspred.bsky.social · 06/02/2025
Currently, we've curated scores from our flagship paper (doi.org/10.1038/s415...), along with recently developed scores for ~3000 Olink proteomic traits from the UKB PPP (preprint incoming). We are collaborating with & curating cognate resources in the community for our next update. Stay tuned!(6/N)
doi.org
An atlas of genetic scores to predict multi-omic traits - Nature
A machine learning approach is used to analyse multi-omics (proteomics, metabolomics and transcriptomics) data, producing genetic scores for more than 17,000 biomolecular traits in human blood, a...
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OmicsPred @omicspred.bsky.social · 06/02/2025
We provide REST APIs to allow users to search and retrieve all OmicsPred metadata, offering flexibility to identify scores, associations, or other entities that meet their specific needs. (5/N)
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OmicsPred @omicspred.bsky.social · 06/02/2025
You can also browse and search for omic trait-phenotype associations identified in the biobank association analyses using the genetically predicted multi-omic traits. (4/N)
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OmicsPred @omicspred.bsky.social · 06/02/2025
Each score has its own page describing the omic trait a score predicts, its linked biological annotations, how the score was developed, samples used for training/testing (with ancestry information) and related performances, and a link to download the score model. (3/N)
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OmicsPred @omicspred.bsky.social · 06/02/2025
On OmicsPred, you can browse and search for multi-omic genetic scores (www.omicspred.org/scores), related publications, omics platforms, and the biological pathways associated with these scores. (2/N)
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OmicsPred @omicspred.bsky.social · 06/02/2025
Introducing a major upgrade to OmicsPred platform (www.omicspred.org) — a resource to enhance the accessibility and usability of genetic scores for multi-omic traits and their phenotypic associations. (1/N)
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