iiinova — where your digital self keeps evolving

Reposted by Øyvind Myrvoll Lorentzen

Christopher Frøhlich @cfr016.bsky.social · 12/07/2026

🧬 I'm looking for a Researcher (2 years) in Molecular Biology and Antimicrobial Resistance at UiT The ❄️Arctic University of Norway (Tromsø). 🔬 If you have experience building and screening enzyme libraries and characterising the variants that come out, get in touch.

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Reposted by Øyvind Myrvoll Lorentzen

John Dennehy @drjdennehy.bsky.social · 12/03/2026

Capturing dynamic phage–pathogen coevolution by clinical surveillance "we capture the acquisition of a parasitic anti-phage mobile genetic element, PLE11, that initiated a selective sweep coinciding with the largest cholera outbreak in recent records. " www.nature.com/articles/s41...

nature.com

Capturing dynamic phage–pathogen coevolution by clinical surveillance - Nature

The acquisition of a parasitic anti-phage mobile genetic element, PLE11, showing potent anti-phage activity against cocirculating ICP1, and the subsequent evolution of ICP1 to escape this defense, are...

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Alberto HCA @albertohca.bsky.social · 10/03/2026

Excited to share our latest work! 📝 We measured the fitness effect of 136 AMR genes and found that many are neutral or even beneficial without selection. 🤯🧬 Oxygen availability can flip their fitness and our stochastic model indicates that oxygen fluctuations help maintain them. Learn more 👇🏼

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Reposted by Øyvind Myrvoll Lorentzen

Kimberly Kline 🏔 @kimingeneva.bsky.social · 23/02/2026

What if quorum sensing doesn’t promote biofilms - but restrains it? 🤔 New work from @harisantypas.bsky.social shows that the Fsr QS system in Enterococcus faecalis acts as a brake on biofilm formation and pathogenesis during infective endocarditis (IE). www.nature.com/articles/s41...

nature.com

Loss of Fsr quorum sensing promotes biofilm formation and worsens outcomes in enterococcal infective endocarditis - Nature Communications

Infective endocarditis (IE) is an understudied biofilm-associated infection. Here, analyses of preclinical and clinical data reveal that the Fsr quorum sensing (QS) system of Enterococcus faecalis is ...

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Christopher Frøhlich @cfr016.bsky.social · 15/02/2026

Sometimes, adaptation to one #antibiotics can make bacteria more vulnerable to other drugs. #CollateralSensitivity. 💡 By following the evolution of a β-lactamase, we uncovered how mutations can both create and mitigate such collateral sensitivity networks. www.biorxiv.org/content/10.6...

biorxiv.org

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Reposted by Øyvind Myrvoll Lorentzen

Jerónimo Rodríguez-Beltrán @jerorb.bsky.social · 27/01/2026

New paper out in @pnas.org, and it made the cover! 👁️ We represent plasmids as circles and mutations as dots, resembling an eye, because in this paper we literally 𝑤𝑎𝑡𝑐ℎ plasmids evolve. ‼️Check Paula’s 🧵 and the paper👇 𝗣𝗹𝗮𝘀𝗺𝗶𝗱 𝗺𝘂𝘁𝗮𝘁𝗶𝗼𝗻 𝗿𝗮𝘁𝗲𝘀 𝘀𝗰𝗮𝗹𝗲 𝘄𝗶𝘁𝗵 𝗰𝗼𝗽𝘆 𝗻𝘂𝗺𝗯𝗲𝗿 www.pnas.org/doi/10.1073/...

Cover of PNAS in which we show plasmids as colourful concentric circles, with dots scattered. The image kind of resembles an eye, although it’s visibly a plot.

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Klebsiella Club @klebclub.bsky.social · 12/01/2026

We’re excited to kick off a new season of the Klebsiella Seminar Series, held on Thursdays in April 🧫🧬! We have 3 sessions on pathogenesis, pediatric Klebsiella & translational approaches. We will also have an open session. Registration is mandatory & FREE in this link forms.gle/LhJu11WQN6Yy... 🔁

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Øyvind Myrvoll Lorentzen @oeyvindml.bsky.social · 14/02/2025

Last project of my PhD is out as a preprint!

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