🚀 Our new preprint is out!
We uncover that TAF15 forms amyloids that propagate in a prion-like manner via defined APR motifs.
• First TAF15 cell biosensor
• Prion-like TAF15 propagation
• Mapping TAF15 aggregation propensity
🔗 www.biorxiv.org/content/10.1...
biorxiv.org
TAF15 amyloids propagate via defined motifs in a prion-like fashion
TATA-box binding protein-associated factor 15 (TAF15) is an RNA-binding member of the FET family recently identified as the primary fibrillar constituent in a subset of frontotemporal lobar degenerati...
