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Nima Mosammaparast

@nimamlab.bsky.social
411 followers 109 following 45 posts

Professor of Pathology at WashU, St. Louis, Co-Director DNA Repair Program @Siteman Cancer Center. Father, husband, immigrant.

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Nima Mosammaparast @nimamlab.bsky.social · 15/04/2026
It is a well-known fact that Vought's daughter has CF. She is taking Trikafta, a combination therapy that has saved her life and those of many others. One can easily draw a line between this drug and the NIH funding (as well as NIH researches) that is holding the disease at bay.
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Nima Mosammaparast @nimamlab.bsky.social · 08/04/2026
Congrats Brooks. I really like G&D as a journal b/c of maintaining their academic roots.
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Nima Mosammaparast @nimamlab.bsky.social · 03/02/2026
Hahahaha!
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Nima Mosammaparast @nimamlab.bsky.social · 02/02/2026
I'll make you a deal: I'll trade my last Mol Cell for your latest Nature. OK?!?
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Nima Mosammaparast @nimamlab.bsky.social · 28/01/2026
Brings up the "Well, back in my day there was none, so..." kind of thought.
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Nima Mosammaparast @nimamlab.bsky.social · 17/01/2026
Knitting?!?
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Nima Mosammaparast @nimamlab.bsky.social · 13/01/2026
We recently had to say goodbye to Tala, our feisty but beloved grey tabby, at the age of (almost) 18. She had a good life and we will miss her dearly.
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Nima Mosammaparast @nimamlab.bsky.social · 18/12/2025
He forgot one slot...
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Nima Mosammaparast @nimamlab.bsky.social · 17/12/2025
To top off the end of 2025, a new preprint from our lab! We find an unanticipated new answer to an old question in DNA repair. www.biorxiv.org/cgi/content/...
biorxiv.org
Human MutLa activates methylpurine DNA glycosylase to induce alkylation damage cytotoxicity
Alkylation chemotherapy is commonly used against tumors such as glioblastoma, yet resistance often develops through downregulation of mismatch repair (MMR). Previous work has established that loss of ...
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Nima Mosammaparast @nimamlab.bsky.social · 19/09/2025
Take me! Can I be your student?!?
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Nima Mosammaparast @nimamlab.bsky.social · 19/08/2025
A giant will be missed here at WashU. His laboratory was directly above mine. internalmedicine.wustl.edu/obituary-stu...
internalmedicine.wustl.edu
Obituary: Stuart Arthur Kornfeld, MD - John T. Milliken Department of Medicine
October 4, 1936 – August 17, 2025 It is with deep sadness that I share the news that Dr. Stuart Arthur Kornfeld, Professor Emeritus, passed away on Sunday, August 17, 2025, from complications of Parki...
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Nima Mosammaparast @nimamlab.bsky.social · 01/08/2025
Congratulations and very well deserved!
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Nima Mosammaparast @nimamlab.bsky.social · 08/07/2025
I'm sorry I didn't get to unwind with you, @lohman.bsky.social.
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Nima Mosammaparast @nimamlab.bsky.social · 06/06/2025
Yeah, cancer is RUFF!
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Reposted by Nima Mosammaparast
Emily Feng @emilyzfeng.bsky.social · 05/06/2025
"I think we have a bias as people coming from the tech industry where we worked at companies, you know, such as Google, Facebook, these companies that have plenty of money, are funded by investors and have lots of people kind of sitting around doing nothing." www.npr.org/2025/06/02/n...
npr.org
Former DOGE engineer says federal waste and fraud were 'relatively nonexistent'
NPR's Juana Summers talks with Sahil Lavingia, who worked for the Department of Government Efficiency as a software engineer assigned to the Department of Veterans Affairs, about his experience.
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Nima Mosammaparast @nimamlab.bsky.social · 20/05/2025
Unbelievable.
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Nima Mosammaparast @nimamlab.bsky.social · 18/04/2025
I think he greased his hair with the tears he shed over the spilt milk.
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Nima Mosammaparast @nimamlab.bsky.social · 18/04/2025
Congratulations! Well deserved!
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Nima Mosammaparast @nimamlab.bsky.social · 10/04/2025
Nice! Thank you for highlighting our work!
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Nima Mosammaparast @nimamlab.bsky.social · 03/04/2025
Yum!!! 😂
theonion.com
Trump Informs Nation They Better Start Liking Those Little Canned Wieners
WASHINGTON—Saying that Americans should anticipate certain lifestyle changes as a result of his newly announced tariffs, President Donald Trump informed the nation Thursday that they better start liki...
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Nima Mosammaparast @nimamlab.bsky.social · 01/04/2025
These are the repercussions of the concessions...
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Nima Mosammaparast @nimamlab.bsky.social · 26/03/2025
How about tenure and promotions committees? Is that confidential enough to make it on #signal?
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Nima Mosammaparast @nimamlab.bsky.social · 26/03/2025
It was forty years ago today that I came to the US with my family to escape war and repression in Iran. I remain thankful and amazed at where life has led me. #freedom
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Nima Mosammaparast @nimamlab.bsky.social · 10/03/2025
Excellent!
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Nima Mosammaparast @nimamlab.bsky.social · 09/03/2025
I was unaware - Such an inspiring story!
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Nima Mosammaparast @nimamlab.bsky.social · 09/03/2025
This is why we need science.
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Reposted by Nima Mosammaparast
Hiten Madhani @hitenmadhani.bsky.social · 06/03/2025
Signed. You should too. www.change.org/p/petition-t...
change.org
Sign the Petition
Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)
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Nima Mosammaparast @nimamlab.bsky.social · 05/03/2025
A shoutout to @ningtsao.bsky.social who led this work - and just joined BlueSky! Such a pleasure to have him as part of the group.
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Nima Mosammaparast @nimamlab.bsky.social · 05/03/2025
Thanks, Alice. We miss you here in St. Louis! Hope you are doing well.
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Nima Mosammaparast @nimamlab.bsky.social · 04/03/2025
Also, nice pun your worked in there! But as my daughter would say to me, "That's a daddy joke".
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Nima Mosammaparast @nimamlab.bsky.social · 04/03/2025
Thank you, Jennie.
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Nima Mosammaparast @nimamlab.bsky.social · 04/03/2025
Thanks for the shoutout, Hiten. There are several limitations to the work, but we think our data generally supports the model. Would be happy to hear any feedback.
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Nima Mosammaparast @nimamlab.bsky.social · 04/03/2025
Thanks Martijn. Although I’ll always be jealous of your labs’ amazing productivity!! Maybe once the NIH is gone, I can come and be your student?!?
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Nima Mosammaparast @nimamlab.bsky.social · 04/03/2025
Thanks, Barbara. Looking forward to seeing you in October!
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Nima Mosammaparast @nimamlab.bsky.social · 03/03/2025
A great pleasure to share our newest paper out this morning @cp-molcell.bsky.social. We show that damage to nascent RNAs should not be ignored, and under certain conditions, these can turn into DNA breaks. We call this phenomena RDIBs (RNA Damage Induced Breaks). www.cell.com/molecular-ce...
cell.com
YTHDC1 cooperates with the THO complex to prevent RNA-damage-induced DNA breaks
Tsao et al. uncover a novel pathway for genotoxicity, termed RNA-damage-induced DNA breaks (RDIBs). The mechanism for preventing RDIBs is orchestrated by YTHDC1 along with the THO complex, which funct...
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Nima Mosammaparast @nimamlab.bsky.social · 13/02/2025
New recipe for the family: Parmesan risotto with roasted beets and pistachios. #success
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Nima Mosammaparast @nimamlab.bsky.social · 30/01/2025
Make rubella great again.
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Nima Mosammaparast @nimamlab.bsky.social · 28/01/2025
Unfortunately if Hegseth can get in, RFK will likely follow.
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Nima Mosammaparast @nimamlab.bsky.social · 27/01/2025
Anyone else stocking up on #Covfefe?!?
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Nima Mosammaparast @nimamlab.bsky.social · 26/01/2025
Rudolf the white nosed pancake, had a very shiny nose…
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Nima Mosammaparast @nimamlab.bsky.social · 23/01/2025
I am planning to make it through the #NIH freeze with some creative adult beverages. Any suggestions?!?
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Nima Mosammaparast @nimamlab.bsky.social · 14/12/2024
I was thinking (hoping?!?) the “F” stood for something else. 😂😂
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Nima Mosammaparast @nimamlab.bsky.social · 30/11/2024
I agree it is more important than ever. Imagine the people doing research to mass produce penicillin during WWII, and how many lives this saved. They had purpose - and we need to find our purpose irrespective of what is happening around us.
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Nima Mosammaparast @nimamlab.bsky.social · 19/11/2024
Great to have you nearby, Orlando.
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Nima Mosammaparast @nimamlab.bsky.social · 14/11/2024
So tonight I'm going to sketch a plan about my next grant using worms as a model system.
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Nima Mosammaparast @nimamlab.bsky.social · 14/11/2024
Thanks, Peter. Looking forward to your visit here!
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Nima Mosammaparast @nimamlab.bsky.social · 14/11/2024
If it wasn't clear already, I hope my first post here makes it clear what I do and love.
annualreviews.org
RNA Damage Responses in Cellular Homeostasis, Genome Stability, and Disease | Annual Reviews
All cells are exposed to chemicals that can damage their nucleic acids. Cells must protect these polymers because they code for key factors or complexes essential for life. Much of the work on nucleic...
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