Abstract. Eukaryotic cell division is regulated by CDK activity that must reach critical CDK threshold levels to progress through cell cycle stages. In low

Abstract. Eukaryotic cell division is regulated by CDK activity that must reach critical CDK threshold levels to progress through cell cycle stages. In low

PhD Project - Investigating chronic inflammation caused by asbestos-like fibres as a driver of mesothelioma at Lancaster University, listed on FindAPhD.com

Three BRAF inhibitors are used to treat melanoma and colorectal cancer. Here, the authors demonstrate that these drugs bind and activate the protein kinase GCN2, a previously unappreciated off-target ...

Nature Structural & Molecular Biology - DNA damage can be sensed as a danger signal by the innate immune system. Bournique et al. show that the transcription stress caused by DNA lesions can...

Nature Structural & Molecular Biology, Published online: 11 April 2025; doi:10.1038/s41594-025-01525-5DNA damage can be sensed as a danger signal by the innate immune system. Bournique et al. show that the transcription stress caused by DNA lesions can also initiate inflammation by causing the direct release of cytokine IL-1α, which then drives NF-κB activation in neighboring cells.

PhD Programme - Natural Sciences PhD opportunities at Lancaster University, listed on FindAPhD.com

PhD Project - Staying alive: how do trypanosome parasite mitochondria deal with stress? at Lancaster University, listed on FindAPhD.com

Deep learning methods have been used to design proteins that can neutralize the effects of three-finger toxins found in snake venom, which could lead to the development of safer and more accessible an...

Bacterial TAXI-TRAP transporters are widespread but poorly understood. Davies et al. characterize a TAXI from Vibrio cholerae, revealing its glutamate spec