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Nicolas Captier

@nicolascaptier.bsky.social

14 followers 13 following 2 posts

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Reposted by Nicolas Captier

Lucie GB. @lgaspardboulinc.bsky.social · 19/05/2025

🚨Thrilled to finally see our review "Cell-type deconvolution methods for spatial transcriptomics" published in @NatureRevGenet @SpringerNature nature.com/articles/s41... (read free: rdcu.be/el0Ka). Check out our web-tool: cavallilab-curie.shinyapps.io/Review-Deconvo

Cell-type deconvolution methods for spatial transcriptomics - Nature Reviews Genetics

Cell-type deconvolution methods are often needed to analyse spatial transcriptomic data to recover cell-type distributions. In this Review, the authors describe the process of cell-type deconvolution,...

Reposted by Nicolas Captier

Institut Curie @institutcurie.bsky.social · 04/02/2025

In a recent study published in @naturecomms.bsky.social, researchers from @institutcurie.bsky.social Inserm, and @minesparis-psl.bsky.social developed an #AI model integrating multiple data types to improve the prediction of response to immunotherapy in #lungcancer. www.nature.com/articles/s41...

Integration of clinical, pathological, radiological, and transcriptomic data improves prediction for first-line immunotherapy outcome in metastatic non-small cell lung cancer - Nature Communications

Overall survival in metastatic non-small cell lung cancer is improved by immunotherapy but individual responses widely vary, and predictive biomarkers are urgently needed. Here authors show that multi...

Reposted by Nicolas Captier

Matthieu Najm @mattanajm.bsky.social · 20/12/2024

Excited to share the final work from my PhD: our study on developing a signalling network gathering the molecular dysregulations caused by the absence of CFTR in cystic fibrosis (CF). Read the full article published in the journal BMC Genomics at: doi.org/10.1186/s128... 1/5

From CFTR to a CF signalling network: a systems biology approach to study Cystic Fibrosis - BMC Genomics

Background Cystic Fibrosis (CF) is a monogenic disease caused by mutations in the gene coding the Cystic Fibrosis Transmembrane Regulator (CFTR) protein, but its overall physio-pathology cannot be sol...

Nicolas Captier @nicolascaptier.bsky.social · 14/01/2025

Our latest #research on multimodal prediction of #immunotherapy outcome in #lungcancer is now published in @natureportfolio.bsky.social ! It comes with publicly available data to reproduce and extend our experiments: doi.org/10.5281/zeno... @institutcurie.bsky.social, @fondationarc.bsky.social

Integration of clinical, pathological, radiological, and transcriptomic data improves prediction for first-line immunotherapy outcome in metastatic non-small cell lung cancer

This repository contains the radiomic, pathomic, and transcriptomic features used in: "Integration of clinical, pathological, radiological, and transcriptomic data improves prediction for first-line i...

Reposted by Nicolas Captier

Institut Curie @institutcurie.bsky.social · 09/01/2025

📣 Registration is now open for the next radiomics course at @institutcurie.bsky.social! Join us for a 3-day training that combines theory and hands-on practice with LIFEx. Limited to 20 on-site participants, so register early! 👉 training.institut-curie.org/courses/radiomics-theory-and-practice

Nicolas Captier @nicolascaptier.bsky.social · 13/01/2025

Excited to share our latest #research from @institutcurie.bsky.social on multimodal prediction of #immunotherapy outcome in #lungcancer, published with @springernature.bsky.social in @naturecomms.bsky.social rdcu.be/d56Fn @fondationarc.bsky.social & [PRAIRIE Institute](prairie-institute.fr)

Integration of clinical, pathological, radiological, and transcriptomic data improves prediction for first-line immunotherapy outcome in metastatic non-small cell lung cancer

Nature Communications - Overall survival in metastatic non-small cell lung cancer is improved by immunotherapy but individual responses widely vary, and predictive biomarkers are urgently needed....