OpenAI chief scientist also among authors of report on prospect of ‘most consequential technological development in history’

The findings provide a new perspective on how granule cells in the cerebellum help to generalize across tasks.

Extracting interpretable mathematical models from complex dynamical systems is difficult, especially for chaotic dynamics observed with noisy experimental data. We present PEM-UDE, a method that combi...

An expert at the University of Copenhagen said his team had been sharing its research with the company’s A.I. model, Claude, and that its new finding matched their work.

The assumption that waking life consists of a stream of conscious representations has inadvertently led consciousness science to its current impasse.

Some of the least understood phenomena in the brain emerge from interactions between local and global brain states, yet representing their joint activity is a considerable computational challenge. As ...

The transcription factors a <em>Drosophila</em> neuron expresses offer clues to its lineage and birth order—and ultimately how neural circuits emerge.

Scientific Reports - Two distinct excitability types delineate the partition between normal brain function, engram encoding, and the two phases of hyperexcitability/epileptic susceptibility

The organoids show shifts in gene expression along the anterior-posterior axis that match those seen during the second trimester of fetal development.

Essential cognitive processes like attention, memory, and decision-making require the brain to perform many operations simultaneously. Disentangling the neural mechanisms underlying these processes is...

Biocomputational method; Bioinformatics; Biological sciences; Computer science; Neural networks; Neuroscience

Scientists have a history of trying — and failing — to link biology and quantum mechanics. The real connection between them may be in the math.

Various genes show distinct exits and entrances with age in the open- source dataset, the largest of its kind to date.

The models recapitulate many key developmental processes, but some radial glial cells in mouse organoids make neurons earlier than they should.

Hundreds of physicists (and a few journalists) journeyed to Helgoland, the birthplace of quantum mechanics, and grappled with what they have and haven’t learned about reality.

Random noise can break symmetries and enhance the stability of collective behaviors

A 1987 Cell paper inspired Ardem Patapoutian to think about the molecular codes that define neuronal subtypes.

Today’s computers need safeguards against random energy fluctuations. Thermodynamic computers would put those fluctuations to use.

Scaffolded DNA Computer performs diverse computations while thermodynamically relaxing towards equilibrium, demonstrating simplicity, reusability, speed,&nbsp;robustness and scalability of the approac...

New experiments reveal how astrocytes tune neuronal activity to modulate our mental and emotional states. The results suggest that neuron-only brain models, such as connectomes, leave out a crucial la...

Abstract. Conscious experience depends on the coordinated activity of neural processes that span multiple scales: from synapses to whole-brain dynamics. A recently introduced measure, dynamical indepe...

Consciousness needs a subject - Volume 49

Europe PMC is an archive of life sciences journal literature.

Podcast Episode · The Joy of Why · September 17 · 47m

The chimeric mice could help untangle the biology of human brain development or conditions such as autism.

Background Ephaptic coupling is a relatively underexplored mechanism of neuronal interaction mediated by perturbations of the extracellular electric potential without the formation of conventional che...

Recent years have witnessed major advances in our understanding of the distinct functional and computational roles of the ventral hippocampus (vHPC). Mazen Kheirbek and colleagues examine the state-de...

At Blackrock Neurotech, Spencer Kellis develops implantable devices that help people with brain and spinal cord conditions communicate, move and more.

The people who work in AI are not gurus and most of their predictions have been wrong. Working in the industry makes them less reliable commentators, not more

Infantile amnesia is not simply a story about forgetting the past. It is an opportunity to understand how memory itself is built.

Using a combined approach of monkey electrophysiology, artificial neural networks and human psychophysics, Xue et al. show that neuronal interference from irrelevant information underlies behavioral e...

As more researchers come forward to warn of the existential danger posed by the technology, governments must act now to ensure humanity maintains the upper hand

Neural network models can express computational hypotheses about brain information processing, but their high parametric capacity makes discriminating model alignment to experimental data challenging....

Using experiments and theory, the authors examine how olfactory memories are encoded in the zebrafish olfactory cortex. They find that experience reshapes the internal map of odor space, making releva...

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Despite large-scale recordings, neuroscience has identified representations for only a small fraction of visual features distinguishable by humans. This is increasingly attributed to mixed selectivity...

The genomic regions regulating gene expression are often themselves transcribed into a variety of noncoding RNAs (ncRNAs). However, the regulatory roles of this noncoding transcription remain largely unknown. By using live imaging, we reveal that the ...

The authors develop SORDINO, a silent, sensitive and distortion-free fMRI method. They benchmark the technique against conventional approaches, reveal its functional contrast mechanisms and use it to ...

Traveling waves (TWs) are widely observed in the brain and are thought to play multiple functional roles, yet what LFP traveling waves represent remains unclear. Using translaminar recordings in macaq...

Neural activity does not always lie in a low-dimensional subspace. The authors extend this classic view to show that task-relevant information is distributed across multiple covariability classes and ...

The community stagnates without the impulse of the individual. The impulse dies away without the sympathy of the community.” — William James, The Will to