Reposted by Laura Fumagalli
C9orf72 mutations impair immune activation in ALS, highlighting key differences in the cellular and molecular pathways underlying sporadic and genetics forms of the disease
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www.nature.com/articles/s41...
nature.com
C9orf72 hexanucleotide repeat expansions impair microglial response in ALS - Nature Neuroscience
This study shows that C9orf72 mutations impair immune activation in ALS, affecting how brain cells communicate, and highlights key differences in the cellular and molecular pathways underlying sporadi...