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Baoling Lai @baolinglai.bsky.social · 15/10/2025

ASTROCYTES POWER DOWN! Our new in vivo paper shows that sustained GPCR activation in astrocytes during learning drains their ER calcium reserves. This is a critical new discovery for understanding how glia shape memory. Check out the full story below! www.nature.com/articles/s41...

nature.com

Astrocytic Ca2+ prevents synaptic depotentiation by limiting repetitive activity in dendrites during motor learning - Nature Neuroscience

Lai et al. show a function of astrocytic Ca2+ in preventing synaptic depotentiation by reducing repetitive dendritic activity in the motor cortex during motor training, thereby contributing to learnin...

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