Genome-wide analysis coupled with long-read sequencing identifies a repeat expansion in GOLGA8A associated with high risk for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusi...

<p>Nature, Published online: 28 January 2026; <a href="https://www.nature.com/articles/s41586-025-09984-y">doi:10.1038/s41586-025-09984-y</a></p>Muscularis macrophages, housekeepers of enteric nervous system integrity and intestinal homeostasis, modulate α-synuclein pathology and neurodegeneration in models of Parkinson’s disease, and understanding the accompanying mechanisms could pave the way for early-stage biomarkers.

Description The laboratory of Microglia and Inflammation in Neurological Diseases (MIND), headed by Renzo Mancuso, is a part of the VIB-Center for Molecular Neurology (CMN) and focuses on multiple aspects of microglial biology and neuroinflammation in Alzheimer’s disease, frontotemporal