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Mathias Munschauer

@munschauerlab.bsky.social
437 followers 195 following 20 posts

Professor at Heidelberg University (@uniheidelberg.bsky.social). Director Molecular Virology. Interested in RNA viruses, RNA-binding proteins and RNA medicine. www.munschauerlab.de

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Mathias Munschauer @munschauerlab.bsky.social · 02/07/2026
We offer an ambitious, collaborative, and international research environment with the freedom to build your scientific vision. You'll find outstanding colleagues, world-class infrastructure, and a department with bold scientific ambitions. Sounds exciting? We'd love to hear from you.
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Mathias Munschauer @munschauerlab.bsky.social · 02/07/2026
This isn't just another faculty position. It's an opportunity to define the next chapter of hepatitis virus research in one of Europe's leading environments for virology and infectious diseases.
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Mathias Munschauer @munschauerlab.bsky.social · 02/07/2026
One of the best parts of leading a department is the opportunity to recruit exceptional people who will shape its future. Today, I'm thrilled to share that we are recruiting a W3 Professor of Translational Hepatitis Virus Research at Heidelberg University. www.nature.com/naturecareer...
nature.com
W3 Professorship in Translational Hepatitis Virus Research (m/f/d) - Heidelberg, Baden-Württemberg (DE) job with WESTPRESS GmbH & Co. KG | 12861212
The Heidelberg Medical Faculty of the University of Excellence Heidelberg is an outstanding location for innovative research, both nationally and i...
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Mathias Munschauer @munschauerlab.bsky.social · 01/10/2025
🚀We’re hiring! Join our international team at @ciid-heidelberg.bsky.social and @uniheidelberg.bsky.social as a PhD Student or Postdoctoral Researcher to lead cutting edge research projects at the virus-host interface Postdoc: tinyurl.com/d5sdhbnp PhD: tinyurl.com/bdz5e5u6
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Mathias Munschauer @munschauerlab.bsky.social · 11/07/2025
Thanks a lot Marco!
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Mathias Munschauer @munschauerlab.bsky.social · 11/07/2025
Thanks a lot Stefan!
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Mathias Munschauer @munschauerlab.bsky.social · 01/07/2025
We’re gearing up to grow the Heidelberg team and will soon post several exciting positions. Stay tuned! 4/4
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Mathias Munschauer @munschauerlab.bsky.social · 01/07/2025
A huge thank you to my mentors, colleagues & friends, and especially my team - your hard work got us here. Also, many thanks to the broader virology community; it’s a privilege to contribute to such an amazing and dynamic field. 3/4
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Mathias Munschauer @munschauerlab.bsky.social · 01/07/2025
I’m excited to take on this new task and look forward to working alongside the incredible teams at the Center for Integrative Infectious Disease Research (@ciid-heidelberg.bsky.social) and across the Heidelberg Medical Campus. 2/4
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Mathias Munschauer @munschauerlab.bsky.social · 01/07/2025
Big personal news: Today I’ve started as Full Professor & Director of the Molecular Virology Department at Heidelberg University (@uniheidelberg.bsky.social). 1/4
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Reposted by Mathias Munschauer
Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 12/12/2024
The #HIRI & the Faculty of Medicine at the University of Würzburg jointly open a call for 3 HELMHOLTZ RESEARCH GROUPS WITH JUNIOR PROFESSORSHIPS (W1) in the areas of 🔹RNA-based Infection Research 🔹Microbial RNA Biology 🔹RNA-based Medicine Apply by January 19 at www.helmholtz-hiri.de/en/w1-groups/
© DORANTHPOST
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Reposted by Mathias Munschauer
Helmholtz Institute Würzburg @helmholtz-hiri.bsky.social · 28/06/2024
A daring email took @munschauerlab.bsky.social from Mannheim to New York, to the lab of one of the world’s most renowned #RNA researchers. 👨‍🔬🧬 Today, he is one of the most sought-after experts in the field. Learn more about him in this portrait by @www.helmholtz.de: www.helmholtz.de/en/newsroom/...
helmholtz.de
On the trail of RNA
A daring e-mail took biochemist Mathias Munschauer from Mannheim to New York, to the laboratory of one of the world’s most renowned RNA
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Mathias Munschauer @munschauerlab.bsky.social · 12/02/2024
In conclusion, SHIFTR enables the systematic mapping of region-resolved RNA interactomes for any RNA in any cell type and has the potential to revolutionize our understanding of transcriptomes and their regulation.
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Mathias Munschauer @munschauerlab.bsky.social · 12/02/2024
Using SHIFTR, we identify interactions of the 5′ and 3′-terminal regions of authentic SARS-CoV-2 RNAs produced during infection and accurately recover known and novel RNA interactors.
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Mathias Munschauer @munschauerlab.bsky.social · 12/02/2024
SHIFTR works for RNAs of different length and abundance (snRNAs, lncRNAs, mRNAs) and is compatible with sequentially releasing interactomes for multiple target RNAs in a single experiment.
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Mathias Munschauer @munschauerlab.bsky.social · 12/02/2024
Proteins bound to a specific RNA can be released from interphase extracts by selectively degrading the RNA of interest, for instance with RNase H + specific DNA probes. Loss of the RNA leads to a SHIFT of crosslinked proteins to the organic phase in the next extraction step.
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Mathias Munschauer @munschauerlab.bsky.social · 12/02/2024
In brief, SHIFTR relies on the sequence-independent isolation of crosslinked RNA-protein complexes by organic phase separation as described in OOPS, XRNAX, or PTex.
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Mathias Munschauer @munschauerlab.bsky.social · 12/02/2024
With SHIFTR you can identify proteins directly bound to a specific region within any endogenous RNA. In addition to delivering region-resolution, SHIFTR requires orders of magnitude lower input material compared to the state-of-the-art, thus removing a critical bottleneck.
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Mathias Munschauer @munschauerlab.bsky.social · 12/02/2024
Time to SHIFT to BlueSky and share our recent paper introducing SHIFTR, a novel platform for region-specific RNA interactome discovery developed by PhD student Jens Aydin 👨‍🔬 in my group. Now published in Nucleic Acid Research: academic.oup.com/nar/advance-...
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Mathias Munschauer @munschauerlab.bsky.social · 04/10/2023
Big shout-out to the lab members leading this effort @Helmholtz_HIRI @Helmholtz_HZI: Nora Schmidt, Sabina Ganskih, Yuanjie Wei and Alex Gabel. We are immensely grateful to our collaborators and funders @ERC_Research and the Helmholtz Association.
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Mathias Munschauer @munschauerlab.bsky.social · 04/10/2023
In brief, the host protein SND1 binds the negative-sense RNA intermediates of SARS-CoV-2 and promotes viral RNA synthesis through recruitment of NSP9, which acts as a protein primer for RNA production 🤯.
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Mathias Munschauer @munschauerlab.bsky.social · 04/10/2023
Hello BlueSky 👋. Time for our first paper alert 🚨: Thrilled to share the latest work from my group revealing how a host RNA-binding protein orchestrates SARS-CoV-2 RNA synthesis in human cells. Now out in Cell @CellPress: www.cell.com/cell/fulltex...
cell.com
SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9
Mapping of subgenome-resolved SARS-CoV-2 RNA-protein interactions reveals that the host protein SND1 binds negative-sense SARS-CoV-2 RNA and promotes viral RNA synthesis by recruiting NSP9, which like...
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