Melanie Tschiersch @mtschiersch.bsky.social · 25/08/2026Thanks a lot! Glad you find it interesting! 000
Melanie Tschiersch @mtschiersch.bsky.social · 24/08/20268/n This work would not have been possible without many hours of discussions with the amazing Albert Compte and the fantastic @jbarbosa.org, the great collaboration with Matt Smith and the hard work from Akash Umakantha and Ryan Williamson. For more details, check out the article or message me!😊 131
Melanie Tschiersch @mtschiersch.bsky.social · 24/08/20267/n But why is this useful? Let's think in terms of hard drives: If you have enough space (below capacity), a redundant backup is useful. However, if you run out of space, you'd prioritize new information over backups. Similarly, it can be useful for hemispheres to flexibly adapt to storage demands! 131
Melanie Tschiersch @mtschiersch.bsky.social · 24/08/20266/n We tested whether we could observe this shift in human behavior in a multi-item task. Indeed, memories were more distracted by items in the same hemifield at high loads, but not at low loads, consistent with a flexible storage strategy that adapts to changing cognitive demands. 121
Melanie Tschiersch @mtschiersch.bsky.social · 24/08/20265/n This got us thinking: If redundant hemispheres can be independently activated, could they shift between being “redundant” and “specialized”? When we pushed the model to capacity (with weak stimulus lateralization), we indeed observed a shift towards hemispheric specialization. 111
Melanie Tschiersch @mtschiersch.bsky.social · 24/08/20264/n We implemented a two-area, redundant attractor network and replicated the findings. The model further predicted that history effects (serial dependence) can remain private in each area if hemispheres are independently activated. A finding that we replicated in the data. 131
Melanie Tschiersch @mtschiersch.bsky.social · 24/08/20263/n We analyzed simultaneous bilateral recordings in macaque PFC and found that both hemispheres stored items simultaneously and equally guided behavioral errors. At the same time, errors were only weakly correlated across hemispheres. Overall, this suggested redundant, weakly coupled hemispheres. 111
Melanie Tschiersch @mtschiersch.bsky.social · 24/08/20262/n Recent evidence repeatedly suggests two opposing models of hemispheric organization: A "specialized" model where each hemisphere mostly stores contralateral information and a "redundant" one, where both hemispheres store information across the full visual field. But how can both things be true? 111
Melanie Tschiersch @mtschiersch.bsky.social · 24/08/2026Our paper "Redundant prefrontal hemispheres adapt storage strategy to working memory demands" is finally out in Nature Communications! We combined bilateral PFC recordings, modeling and human data to ask: How do the hemispheres work together to store information?1/n www.nature.com/articles/s41...nature.comRedundant prefrontal hemispheres adapt storage strategy to working memory demands - Nature CommunicationsNeural mechanisms underlying spatial working memory are not fully understood. In this manuscript, simultaneous bilateral monkey recordings and attractor networks show how weakly coupled, redundant pre... 24713
Reposted by Melanie TschierschBalma Serrano Porcar @balmaserrano.bsky.social · 17/01/2026I am very excited to share my first preprint🎉 The pandemic kicked off strongly during the first year of my PhD, and I had to stop the behavioral experiments when mice were starting to understand the task. At the BCB Lab, this showed us that training automation could be a real game changer (🧵1/10) 1219
Reposted by Melanie TschierschAnne Urai @anne-urai.bsky.social · 11/12/2024Fresh out: a short review article where I give an overview of different ways that across-trial temporal structure is helpful in understanding cognitive models of decision-making osf.io/preprints/ps... 110233
Reposted by Melanie TschierschDr. Jens Foell @jensfoell.de · 18/02/2025For everyone voting in Germany this Sunday: Check out this thread to learn about the different political parties' positions on science communication 1157
Reposted by Melanie TschierschYanis Varoufakis @yanisvaroufakis.bsky.social · 18/02/2025UPDATE: It's happening now. German police entered the new venue to break up our meeting with Francesca Albanese and Amnesty International. The miss no chance to prove that totalitarianism is back in Germany even before the AfD has won gvt 491300660
Reposted by Melanie TschierschTagesschau Bot @tagesschau.bsky.social · 30/01/2025Merz stellt Wahlkampf über demokratische Werte #Kommentar #AfD #CDUtagesschau.deMerz stellt Wahlkampf über demokratische WerteMit ihrem Verhalten im Bundestag hat die Union einen demokratischen Tabubruch begangen, meint Max Bauer. 1315528
Reposted by Melanie TschierschOisín McGann @oisinmcgann.bsky.social · 22/01/2025This Cybertruck did not crash. It made a heartfelt and perhaps ill-advised gesture that, in the moment, might have been misinterpreted as a crash, but we should not rush to judgement. 622288855201
Melanie Tschiersch @mtschiersch.bsky.social · 21/01/2025Thank you so much, Seán! It's been a long time in the making but finally getting somewhere! 000
Reposted by Melanie TschierschJoao Barbosa @jbarbosa.org · 20/01/2025Thanks to the yield of U arrays, we were able for the 1st time AFAIK to average across neurons (not trials) and see memory bumps on single trials. Look at this 😍 Not the focus of the work but it taps into an open debate on the neural mech. of WM cf @cconstan.bsky.social @earlkmiller.bsky.social 0337
Melanie Tschiersch @mtschiersch.bsky.social · 20/01/2025🗯️Taken together, this shows that prefrontal hemispheres can adjust to varying task demands with a simple underlying architecture! If you're interested in more details, check out the preprint or send me a message! Also a HUGE shout-out to everyone involved.It's been (and will continue) fun!🎉 END/🧵 110
Melanie Tschiersch @mtschiersch.bsky.social · 20/01/2025Well... turns out REDUNDANT hemispheres can also replicate this effect!! So it seems that redundant, weakly connected hemispheres can provide increased precision (redundancy) when WM demands are low and increased capacity (weak connections) when WM demands are high. 7/🧵media.tenor.coma man is making a funny face while holding his finger to his head .ALT: a man is making a funny face while holding his finger to his head . 110
Melanie Tschiersch @mtschiersch.bsky.social · 20/01/2025When inputs were slightly lateralized, the model showed that each hemisphere stores the stronger contra- over a weaker ipsilateral input when WM capacity is reached. Remember from 2/ where I said the bilateral field advantage was seen as evidence for non-redundant, independent hemispheres?? 6/🧵 100
Melanie Tschiersch @mtschiersch.bsky.social · 20/01/2025This got us thinking: This model can represent the same memory redundantly, but also maintains history drift privately, allowing for private and shared memories. What does this mean when multiple items need to be remembered?🤔 5/🧵 100
Melanie Tschiersch @mtschiersch.bsky.social · 20/01/2025we modeled two redundant spiking bump attractor networks with inter-area connections and replicated the data if connections were tuned and weak. Furthermore, 🖥️model + 🐒data were in agreement that weak connections lead to private history attraction (serial dependence) in each hemisphere. 4/🧵 100
Melanie Tschiersch @mtschiersch.bsky.social · 20/01/2025We first found that both hemispheres stored (bump-like FR in the figure) and guided behavior for the full visual field suggesting redundant hemispheres. Additionally, neural traces were only weakly correlated across hemispheres suggesting weak coordination between hemispheres... 3/🧵 110
Melanie Tschiersch @mtschiersch.bsky.social · 20/01/2025How do prefrontal hemispheres support continuous spatial WM when visual inputs come strongly lateralized?🤔 Previous studies suggest: 1️⃣ Independent hemispheres:Larger capacity across hemifields (bilateral field advantage)? 2️⃣ Redundant hemispheres:Unilateral opto-disruption doesn’t impair behavior?2/🧵 100
Melanie Tschiersch @mtschiersch.bsky.social · 20/01/2025🚨Excited to share my first @biorxivpreprint.bsky.social🚨 with the amazing Smith lab, @jbarbosa.org and Albert Compte who made this work possible. We show that 🐒prefrontal hemispheres combine redundancy (for precision) & weak connections (for capacity) for supporting spatial working memory (WM). 1/🧵 13313
Reposted by Melanie TschierschbioRxivpreprint @biorxivpreprint.bsky.social · 17/01/2025Redundant, weakly connected prefrontal hemispheres balance precision and capacity in spatial working memory www.biorxiv.org/content/10.1101/202… 062
Reposted by Melanie TschierschJoao Barbosa @jbarbosa.org · 19/01/2025Thrilled to share my first co-last author paper 🥹 Lead by the amazing @mtschiersch.bsky.social 👸, we investigate how both 🐒PFC interact during working memory. Her work sheds light into WM mechanisms by reconciling previous contradictions. Tune in for 🐒WM, serial dependence and attractor models 1242
Melanie Tschiersch @mtschiersch.bsky.social · 20/01/2025good luck! Tagesschau says they are sceptical it will even arrive at all... but fingers crossed! 010
Melanie Tschiersch @mtschiersch.bsky.social · 16/01/2025German's living abroad, we've got until the 2nd of February to register for the elections but it might still be tight that our votes count in the end. Anyways... better safe than sorry, so register at your last Meldestelle:) 120
Reposted by Melanie TschierschAndreas Geiger @andreasgeiger.bsky.social · 15/01/2025Excited to share that today our paper recommender platform www.scholar-inbox.com has reached 20k users! We hope to reach 100k by the end of the year.. Lots of new features are being worked on currently and rolled out soon. 1219026
Reposted by Melanie TschierschDr. Jens Foell @jensfoell.de · 16/01/2025About 5 weeks between now and German parliamentary elections. And I'm seeing the exact same dynamics here that recently murdered what was left of US democracy. 3 things to watch out for: 1/5 13813
Reposted by Melanie TschierschJoao Barbosa @jbarbosa.org · 12/01/2025Check our latest in which we leverage shape metrics to compare neural geometry across regions, sessions or subjects and how their differences predict behavior. w/ Nejatbakhsh, Duong, @sarah-harvey.bsky.social, Brincat, @siegellab.bsky.social, @earlkmiller.bsky.social & @itsneuronal.bsky.social 310337
Reposted by Melanie TschierschSpanish Revolution @spanishrevolution.bsky.social · 13/01/2025🌍 El 1% más rico devora “su parte” del planeta en solo 10 días spanishrevolution.net/el-1-mas-rico… Un análisis sobre cómo el 1% más rico contribuye al colapso climático sin asumir las consecuencias, mientras el resto lucha por sobrevivir.spanishrevolution.netEl 1% más rico devora "su parte" del planeta en solo 10 díasMientras la mayoría lucha por sobrevivir, los más privilegiados aceleran el colapso climático sin pagar las consecuencias. 410661
Reposted by Melanie TschierschSpanish Revolution @spanishrevolution.bsky.social · 14/01/2025 12771331
Reposted by Melanie TschierschDorothy Bishop @deevybee.bsky.social · 14/01/2025Wow, just wow. V different approach reveals numerous problems in Scientific Reports - cf deevybee.blogspot.com/2024/10/an-o... I do hope @springernature.bsky.social will start to publish reviewer reports and editor info as we suggesteddeevybee.blogspot.comAn open letter regarding Scientific Reports16th October 2024 to: Mr Chris Graf Research Integrity Director, Springer Nature and Chair Elect of the World Conference... 29650
Melanie Tschiersch @mtschiersch.bsky.social · 03/01/2025A reminder to the Germans living abroad: It's time to register to vote for the next elections. You just need to send this document to your last Meldestelle so they can send you the voting equipment when it's time:) www.bundeswahlleiterin.de/mitteilungen...bundeswahlleiterin.deBundestagswahl 2025: Antragsformular für Deutsche im Ausland - Die Bundeswahlleiterin 011
Reposted by Melanie TschierschMicah G. Allen @micahgallen.com · 02/12/2024Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know! 9385196
Reposted by Melanie TschierschScientist Rebellion @scientistrebellion.bsky.social · 27/11/2024"This will make it likely that the limit of 1.5C will be surpass in this century". In Germany, scientists are publicly reading the @ipcc.bsky.social AR6 synthesis report at @freieuniversitaet.bsky.social . You can contact your local group to organize a reading. 13913
Reposted by Melanie TschierschJoao Barbosa @jbarbosa.org · 22/11/2024Since no one did it, here is a list of people doing research on working memory. The list is admittedly biased (based on the people I follow), so please help: don't hesitate to let me know of someone missing. I will happily follow and add them to the list! Please RT🙏 go.bsky.app/8ZsVgMo 74621