Reposted by Yuki MochizukiBertoglio lab (FMC/UFSC) @bertogliolab.bsky.social · 25/06/2025Female veterans with military sexual trauma history and posttraumatic stress disorder display impaired fear extinction learning doi.org/10.1016/j.br...doi.orgRedirecting 021
Reposted by Yuki MochizukiSteve Maren @stevemaren.bsky.social · 24/05/2025🚨New paper alert! 🚨 Inactivation of the nucleus reuniens causes relapse of extinguished fear. Here we show this “circuit-induced relapse” depends on hippocampal fear memories and is mediated by hippocampal engrams. Congrats to the team!urldefense.comHippocampal ensembles regulate circuit-induced relapse of extinguished fearMolecular Psychiatry - Hippocampal ensembles regulate circuit-induced relapse of extinguished fear 27122
Reposted by Yuki MochizukiBertoglio lab (FMC/UFSC) @bertogliolab.bsky.social · 15/03/2025The reuniens thalamus recruits recurrent excitation in the medial prefrontal cortex www.pnas.org/doi/10.1073/...pnas.orgThe reuniens thalamus recruits recurrent excitation in the medial prefrontal cortex | PNASThe medial prefrontal cortex (mPFC) and hippocampus are critical for memory retrieval, decision making, and emotional regulation. While ventral CA1... 031
Yuki Mochizuki @moon240.bsky.social · 11/03/2025Thrilled to see my colleague’s excellent paper out now! Time- and sex-dependent effects of juvenile social isolation on mouse ... www.sciencedirect.com/science/arti...sciencedirect.comTime- and sex-dependent effects of juvenile social isolation on mouse brain morphologyDuring early life stages, social isolation disrupts the proper brain growth and brain circuit formation, which is associated with the risk of mental d… 000
Reposted by Yuki MochizukiBertoglio lab (FMC/UFSC) @bertogliolab.bsky.social · 07/03/2025Bidirectional emotional regulation through prefrontal innervation of the locus coeruleus www.nature.com/articles/s41...nature.comBidirectional emotional regulation through prefrontal innervation of the locus coeruleus - Molecular PsychiatryMolecular Psychiatry - Bidirectional emotional regulation through prefrontal innervation of the locus coeruleus 041
Reposted by Yuki MochizukiAlex Shackman @ajshackman.bsky.social · 06/03/2025#Paz Aversive generalization in human amygdala neurons: Current Biology www.cell.com/current-biol...cell.comAversive generalization in human amygdala neuronsOvergeneralizing a learned aversive stimulus can be maladaptive and even contribute to anxiety and PTSD. Reitich-Stolero et al. find that neurons in the human amygdala are involved in this overgeneral... 072
Reposted by Yuki MochizukiJosh Johansen @jojolab.bsky.social · 07/03/2025The first paper from Akira Uematsu's lab (first author @moon240.bsky.social)!: molecularbrain.biomedcentral.com/articles/10.... And check out his lab website: www.uematsu-lab.com/research/molecularbrain.biomedcentral.comDistinct neural responses of ventromedial prefrontal cortex-projecting nucleus reuniens neurons during aversive memory extinction - Molecular BrainAnimals adaptively regulate aversive memories in safe environments through extinction, a process central to exposure therapy for anxiety disorders. The limbic thalamus controls cognitive function in c... 0185
Yuki Mochizuki @moon240.bsky.social · 06/03/2025My first paper has been published! rdcu.be/ecpZ1rdcu.beDistinct neural responses of ventromedial prefrontal cortex-projecting nucleus reuniens neurons during aversive memory extinction | Molecular Brain 010