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Reposted by Saskia Middeldorp

Thomas Reiser @tomreiser.bsky.social · 16/11/2025

Congratulations to @isth.org Councilor @middeldorps.bsky.social on being named & delivering the 2025 Sol Sherry Disting. Lecture in Thrombosis @ the recent @americanheart.bsky.social Scientific Sessions recognizing her role as a foremost clinician & researcher in the field of CV disease & stroke!

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Reposted by Saskia Middeldorp

International Society on Thrombosis and Haemostasis @isth.org · 09/07/2025

📰 Check it out! The @ash.hematology.org and ISTH Updated Guidelines on the Treatment of Pediatric VTE are featured in Hematology Advisor. Don’t miss this spotlight on our collaborative effort! 📖 Read the full feature: www.hematologyadvisor.com/news/pediatr... #PediatricVTE #Hematology #ISTH

hematologyadvisor.com

ASH and ISTH Update Guidelines on Treatment of Pediatric VTE

The ASH and ISTH updated guidelines for treatment of pediatric venous thromboembolism, focusing on improved outcomes and patient quality of life.

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Reposted by Saskia Middeldorp

Thomas Reiser @tomreiser.bsky.social · 25/06/2025

What an inspiring #ISTH2025! It was wonderful to host the global #thrombosis & #hemostasis community in DC. From the latest science & innovations to networking & building new collabs - it had it all! Look out for recordings & other post- @isth.org congress updates. Goodbye & see you @ #ISTH2026!

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Saskia Middeldorp @middeldorps.bsky.social · 25/06/2025

Marc Rodger highlighting the #Highlow study and providing guidance on how to implement the results 👌🏼

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Saskia Middeldorp @middeldorps.bsky.social · 25/06/2025

Now my favourite topic presented eloquently by prof Marc Rodger. Answering all the questions needed for providing well-informed information to your patients. Put the #LMWH needles away in patients with placenta-mediated complications in inherited #thrombophilia! #AFFIRM #ALIFE2 #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 25/06/2025

It took 7 years to recruit 51 patients for the IMPACT single-arm study on certiluzomab on top of LMWH-aspirin shows adverse outcome in 20% which is lower than non-contemporary controls. #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 25/06/2025

More on pregnancy and #APS, now from obstetric perspective. Only 1% of recurrent miscarriage patients had APS antibodies, similar to controls. #ISTH2025

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Marc Carrier, MD @marccarriermd.bsky.social · 24/06/2025

Implementation matters! A guideline-driven VTE prevention program (Vermont Model) led to ~60% of high-risk cancer patients receiving prophylactic anticoagulation—resulting in a 60% reduction in VTE and 56% reduction in death. #ISTH2025 #VTEprevention 🩸 @marycushmanmd.bsky.social

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Saskia Middeldorp @middeldorps.bsky.social · 25/06/2025

Why do we have so little data on pregnancy and thrombotic outcomes in #APS?? Well-illustrated by State-of-the-Art lecture by dr Karen Breen. We MUST do better! #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 24/06/2025

Thanks! I couldn’t make it to the presentation. So, no capping at a maximum dose was applied?

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Marc Carrier, MD @marccarriermd.bsky.social · 24/06/2025

📣 ARIVA Trial at #ISTH2025: 🧪 First RCT on antithrombotic therapy post-venous stenting for PTS 🔵 6-month primary patency rate was higher than expected 💊 No added benefit of aspirin + rivaroxaban vs. rivaroxaban alone www.ahajournals.org/doi/10.1161/...

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Saskia Middeldorp @middeldorps.bsky.social · 24/06/2025

The apicat trial did study apixaban dose reduction VS full dose. That study makes me very comfortable using apixaban in this setting

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Saskia Middeldorp @middeldorps.bsky.social · 23/06/2025

In my experience, young people who don’t take any other meds and are in for the really long term sec prevention, have difficulty being adherent to the evening dose of apixaban

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Reposted by Saskia Middeldorp

Marc Carrier, MD @marccarriermd.bsky.social · 23/06/2025

Meta-analysis on GLP-1RA (vs. placebo) and VTE: 🔹 PE rates significantly lower 📉 🔹 VTE rates lower but not statistically significant 🔹 No difference in DVT 🔹 Study design matters: RCTs vs. observational data Accepted for publication in JTH! #ISTH2025 #VTE #GLP1RA #Thrombosis @jthjournal.bsky.social

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Saskia Middeldorp @middeldorps.bsky.social · 23/06/2025

It’s really worth stopping by our @isth.org booth and get inspired for next year’s meeting in….. Paris! #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 23/06/2025

What started as strong Mendelian observations, has now evolved to a strongly polygenenic etiology of #VTE. Inside and outside the coagulation cascade. #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 23/06/2025

There is more to established #thrombophilia defects in understanding the genetics of venous thromboembolism #VTE. Plenary lecture by Prof Pierre Morange #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 23/06/2025

This was observed during the first 3 months after acute VTE. I’d like to keep the rivaroxaban option for extended treatment for patients who value the once daily regimen and are at low bleeding risk.

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Shematologist, MD @shematologist.medsky.social · 23/06/2025

Tips for asking ?s as moderator #ISTH2025 Clinical talk: what future directions do you see this work taking? Basic science: how do you envision this translating to the clinic? Next level pro tip: contact author beforehand to see what they didn’t have time to present that they’d like you to ask

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Saskia Middeldorp @middeldorps.bsky.social · 23/06/2025

Adjust-DVT study. Only 5% of patients with suspected #DVT had an age-adjusted d-dimer that omits the need for compression ultrasound. I don’t think it is worth it. What do you think? #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 23/06/2025

This is why diagnosing, treating and investigating #APS is so complicated. Massive differences in classification between Sydney 2006 and ACR/EULAR 2023. Only 40% of patients fulfilled the new criteria. What are the implications for future research? #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 23/06/2025

The effects of andexanet on enoxaparin are in line with effects on oral factorXa inhibitors. Great presentation by PhD student Thijs van Haaps #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 23/06/2025

Excellent points ⬇️ Exclusion of pregnant people from trials leads to paradoxical effects! #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 23/06/2025

State-of-the-Art talk bij de Luuk Scheres Despite hormone use being the most prevalent and important risk factor for #VTE in women <50, there is huge underrepresentation of risk models and funding. Food for thought and action 💪🏼 #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 23/06/2025

There is still taboo about discussing menstruation 🩸 There are differences between assessment of abnormal uterine bleeding between professional societies. This is important to realisme and underscores the need to collaborate multidisciplinary. Dr Roseline d’Oiron #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 23/06/2025

Even if you are not a pediatrician, you can learn so much. Beautiful slides on thrombolysis 🤩 Dr Irene Klaassen #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 23/06/2025

Good morning everyone! Another exciting day ahead #ISTH2025. Thirty years ago I visited my first @isth.org Congress. 📣 This morning, I can switch sessions to see two of my former PhD students shine in State-of-the-Art sessions. We take good care of the next generation @isth.org!

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Saskia Middeldorp @middeldorps.bsky.social · 22/06/2025

Interesting data on influence of race from the RIETE registry. After correction for treatment etc, these differences did not show in multi-variate analysis. #ISTH2025

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Reposted by Saskia Middeldorp

Marc Carrier, MD @marccarriermd.bsky.social · 22/06/2025

VTE isn’t “over” at discharge. Many patients face lasting symptoms & distress. 🗣️ PROMs help reveal what matters, if we use them right. ✅ Ask ✅ Act ✅ Guide care Structured models like Attend-PE show the way. #ISTH2025 #Thrombosis #PatientVoice

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Saskia Middeldorp @middeldorps.bsky.social · 22/06/2025

Dragons’s Den of the highly fruitful www.invent-vte.com netwerk. Collaboration leads to practice-changing trials!! #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 22/06/2025

This is what we were waiting for. A direct comparison between apixaban and rivaroxaban for the treatment of acute VTE. Apixaban reduces bleeding risk in the first 3 months by >50%! Practice changing investigator-initiated RCT. #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 21/06/2025

What a fantastic plenary lecture by Prof Jennifer Curnow - in loving and admiring memory of my dear friend Dr Claire McLintock. #ISTH2025

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Reposted by Saskia Middeldorp

Betül Ünlü @betulunlu.bsky.social · 21/06/2025

Kicking off #ISTH2025 with the first falk from RSCI by @aislingrehill.bsky.social on fibrin on trained immunity-associated myeloid cell hypercoagulability @rogerpreston.bsky.social @rcsi.bsky.social

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Saskia Middeldorp @middeldorps.bsky.social · 21/06/2025

Intriguing findings from a high-quality prospective study on SVT in #pregnancy and #postpartum. Incident higher, heterogeneous treatment, but low rate of #DVT and #PE. I was surprised and so were the authors. Would love to see the full results. #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 21/06/2025

OMG I look like I am grilling him - but my questions were meant to be a scientific exchange of ideas 😇

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Saskia Middeldorp @middeldorps.bsky.social · 21/06/2025

Having fun and enjoying excellent science #ISTH2025 now on to my favourite topic #pregnancy and #thrombosis. Interesting cohort study on #LMWH - with therapeutic dose postpartum - still VTE. I think it could be a problem with adherence even though this was assessed by self-reporting

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Saskia Middeldorp @middeldorps.bsky.social · 20/06/2025

Great to be here! #ISTH2025. Looking forward to hearing and supporting all excellent science and scientists from all over the world. #thrombosis

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International Society on Thrombosis and Haemostasis @isth.org · 19/06/2025

🚨 FLASH GIVEAWAY! 🚨 Can’t make it to #ISTH2025 in person? We’ve got you covered. We're giving away a FREE On-Demand Registration and it could be yours! To enter: ❤️ Like this post 💬 Drop a comment Winner announced this Friday! Don’t wait — enter NOW!

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Reposted by Saskia Middeldorp

Thomas Reiser @tomreiser.bsky.social · 20/06/2025

💡Honoring the impact & memory of the late Claire McLintock, this @ISTH.org grant supports #ISTHEarlyCareer innovative research in women's health issues in #thrombosis & #hemostasis. Learn more ⬇️and apply by ⏳ Sept. 1! t.co/QYL9cUcoav Thank you to all donors who supported this grant! #ISTH2025

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Saskia Middeldorp @middeldorps.bsky.social · 19/06/2025

I have been quiet on the socials for a while, but very excited to be on my way to @isth.org #ISTH2025 ✈️. Let's hope that Bluesky gets to fly too! And I also just realized that it has been 30 years since my first @isth.org meeting in 1995. I haven't missed one single congress. #thrombosis

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Thomas Reiser @tomreiser.bsky.social · 14/06/2025

Check out the late-breakthrough abstracts - featuring cutting-edge data from major clinical trials & game-changing studies - to be presented at the @ISTH.org #ISTH2025 congress starting on June 21. It is not too late to register and participate in person or on-demand! Learn more: bit.ly/4jI5oDL

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Is er een dokter in de podcast @dokterinpodcast.bsky.social · 15/06/2025

Luister naar aflevering 20 in je favoriete podcast app. Er is een warme aanbeveling van onze vaste gast @middeldorps.bsky.social Voor de leden van de NIV vergeet morgen niet op haar als nieuwe voorzitter te stemmen op de ALV! #aflevering20 #voorzitters #podcast #poddocs #dip #NIV #stemopmiddeldorp

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Is er een dokter in de podcast @dokterinpodcast.bsky.social · 20/05/2025

De nieuwste aflevering staat online. Hierin een gesprek met @middeldorps.bsky.social als beoogd voorzitter der NIV en @liffertvogt.bsky.social als nieuwe voorzitter van de NfN. Daarnaast nieuws, waar komt die naam vandaan, een verslag uit Vaticaanstad en wijn. Nu in je favoriete podcast app!

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Reposted by Saskia Middeldorp

Dr Dan Shugar 🇨🇦 @watershedlab.bsky.social · 03/04/2025

Reading the first proposal from a prospective trainee where chatGPT was obviously used. The reason I discovered it is b/c I am cited several times, but none of the papers are real. Ugh. People, please don't do this. 🧪⚒️ #AcademicSky

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