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Journal of Thrombosis and Haemostasis

@jthjournal.bsky.social
1.3K followers 75 following 93 posts

The Journal of Thrombosis and Haemostasis (JTH) is the official journal of the ISTH. The mission of JTH is to advance science related to the important medical problems of thrombosis, bleeding disorders and vascular biology. #MedSky #HemeSky #CardioSky

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Reposted by Journal of Thrombosis and Haemostasis
Shematologist, MD @shematologist.medsky.social · 15/04/2026
Confused by the 🚩on your patients CBC? A (pediatric) hematology primer -Thrombocytosis (high platelets) is reactive 99.9999% of the time. Think iron deficiency, infections. Hematologists rarely get excited until it’s multiple millions. 1/
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Dr Satoshi Akima, FRACP @toshiakima.bsky.social · 21/11/2025
Overall, this review highlights the limited evidence supporting the use of anti-Xa monitoring for dose adjustments in the therapeutic use of low-molecular-weight heparins. Therefore, we conclude that measuring anti-Xa levels is currently not justified. @jthjournal.bsky.social
pubmed.ncbi.nlm.nih.gov
A systematic review on anti-Xa monitoring in the therapeutic use of low-molecular-weight heparins - PubMed
Low-molecular-weight heparins are widely utilized, including in special patient populations (eg, patients with renal impairment, pregnancy, and obesity). Monitoring with anti-Xa measurements is often used, but the effectiveness of anti-Xa-based dose adjustments remains uncertain. This systematic rev …
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Thomas Reiser @tomreiser.bsky.social · 24/11/2025
Check out the latest @jthjournal.bsky.social "JTH in Clinic" article providing clinicians w/real-world tools to manage gynecologic bleeding in patients on anticoagulation. Published in collab w/the Found. for Women & Girls w/Blood Disorders, it offers assess. & treatment guidance, bit.ly/4oOoD1N
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Lucy Norris @lucynortcd.bsky.social · 28/11/2025
New treatments have greatly improved survival for #cancer patients but they also come with a risk of #thrombosis. In our new review in @jthjournal.bsky.social we explain why. doi.org/10.1016/j.jt... @wardm6tcd.bsky.social @isth.org.
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Thomas Reiser @tomreiser.bsky.social · 03/12/2025
💡The @isth.org #SSC has been busy - dont miss the latest SSC ✅communications ✅guidance ✅guidelines published in @jthjournal.bsky.social : ℹ️https://bit.ly/4p1GYZz
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Tara Lech, PharmD @anticoagpharmd.bsky.social · 03/12/2025
Excited to share this article highlighting the important role of Antithrombosis Stewardship to improve Safe Transitions of Care in pts with VTE. #Stewardship #Anticoagulation #AntithromboticStewardship #TransitionsofCare @jthjournal.bsky.social @isth.org www.sciencedirect.com:5037/science/arti...
sciencedirect.com
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 16/10/2025
🚨 New RPTH Journal Research Recap! Dive into the latest insights from recent articles. Read ahead: 📄 Full article → lnkd.in/eRJQcZEV 💬 Commentary → lnkd.in/g-q5ZvAa Register here: streamyard.com/watch/WB9QYXi3e3hH This Research Recap is supported by an educational grant from Takeda.
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Cihan Ay @cihanaymd.bsky.social · 29/09/2025
🚀 AI vs. Thrombosis Experts: Who performs better? New study shows: AI models deliver patient education answers that are often rated better than experts — and perform similar in complex clinical cases. @nikola-vladic.bsky.social @jeanconnorsmd.bsky.social @jthjournal.bsky.social
jthjournal.org
Large language models versus thrombosis experts: A comparative study on patient education and clinical decision-making in venous thromboembolism
Large language models (LLMs) have demonstrated remarkable capabilities in various medical fields, yet their performance in thrombosis and haemostasis, particularly in patient education and complex cli...
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MedUni Wien @meduniwien.ac.at · 07/10/2025
🤖🩸 #ArtificialIntelligence in everyday clinical practice: A study by #MedUniVienna shows that language models sometimes provide better answers than experts when it comes to questions about #venousthromboembolism. ⬇️ 📰 Results in @jthjournal.bsky.social​​
meduniwien.ac.at
Artificial intelligence on a par with thrombosis experts
Learn more about the potential and limitations of language models in everyday clinical practice!
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International Society on Thrombosis and Haemostasis @isth.org · 07/10/2025
ISTH is partnering with Inari, now a part of Stryker, for #WorldThrombosisDay 2025! Together we’re advancing #VTE care through a new educational offering: 🎧 The Role of Mechanical Thrombectomy in Transforming VTE Care Launching Oct 16 on the ISTH Pulse Podcast. 🔗 www.worldthrombosisday.org
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 23/09/2025
JTH is proudly supports @worldthrombosisday.bsky.social! Show your commitment to patient safety and awareness this #WorldThrombosisDay on October 13. Share this graphic or create your own image using the WTD Design Hub: www.worldthrombosisday.org/poster-builder/ #WTDay25
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International Society on Thrombosis and Haemostasis @isth.org · 23/09/2025
The ISTH proudly recognizes Global #ITP Awareness Week 💜This year’s campaign theme, "Shining a light on ITP," underscores the importance of visibility and community engagement. #PaintThePlanetPurple #LightUp4ITP 🟣ISTH members: The ISTH offers educational resources about ITP here lnkd.in/debX39MC
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Mary Cushman 🫀🧠🩸 @marycushmanmd.bsky.social · 08/08/2025
1/ 📣 New risk calculator for stroke prediction in #AFib ♥️ Two #REGARDSStudy manuscripts in @jthjournal.bsky.social ♥️ One Identified biomarkers for breakthrough stroke ♥️ In the other we developed a new CHADS-VASc-Biomarkers score @samnotshort.bsky.social go.uvm.edu/strokecalc
go.uvm.edu
New Risk Calculator Can Better Predict Stroke to Direct the Best Prevention | Office of Medical Communications | The University of Vermont
Researchers at the University of Vermont have developed a more precise way to assess stroke risk in people with atrial fibrillation (A-Fib), a condition that affects 10.5 million Americans and is a le...
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VTE Specialist Network @vsnuk1.bsky.social · 29/07/2025
@jthjournal.bsky.social commentary in the most recent issue about more VTE prevention is needed in pregnancy - www.jthjournal.org/article/S153... It will be interesting to see what the new UK 37a green top guidelines advise in the Autumn
jthjournal.org
Venous thromboembolism in pregnancy: more prevention is needed
Pregnancy is a vulnerable period for the health of both mother and child. It is associated with a prothrombotic state, likely a part of an evolutionary development to protect against perinatal bleedin...
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Thomas Reiser @tomreiser.bsky.social · 31/07/2025
💡Turn your exciting research into high-impact publications! Whether you presented at #ISTH2025 &/or have some other new & exciting science to share, watch this interview w/our editors & learn more about submitting to @ISTH.org @jthjournal.bsky.social or @rpth.bsky.social bit.ly/46TLcfk
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International Society on Thrombosis and Haemostasis @isth.org · 06/08/2025
📢📢NEW research from @jthjournal.bsky.social! Two new papers were released on stroke risk and prediction in #atrialfibrillation. Whether you’re a clinician or researcher, you won’t want to miss these insights. Visit jthjournal.org to explore this new research. #stroke #afib #af
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hemehub.bsky.social @hemehub.bsky.social · 08/07/2025
Our webinar with Dr. Jean M. Connors has been rescheduled to August 1st! Don’t miss this opportunity to hear from a top expert in the field! #ISTH2025 #Hematology #MedicalEducation #ClinicalHematology @ash.hematology.org @isth.org @jthjournal.bsky.social @athnnews.bsky.social
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International Society on Thrombosis and Haemostasis @isth.org · 26/06/2025
📚Spotlight on ISTH publications at #ISTH2025: ✅ @rpth.bsky.social: As ISTH’s open-access, online-only journal, RPTH is drives innovation & accessibility in science. ✅ @jthjournal.bsky.social: JTH publishes peer-reviewed groundbreaking research, reviews & clinical guidance Learn more: bit.ly/4k5PbID
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Publications Spotlight: JTH & RPTH
ISTH Publications – Research and Practice in Thrombosis and Haemostasis (RPTH) Research and Practice in Thrombosis and Haemostasis (RPTH) is the open-access, online-only journal of the ISTH. Foll...
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Geoffrey Barnes, MD, MSc @gbarnesmd.bsky.social · 25/06/2025
If you want to learn more about Factor XI inhibitors, check out this recent review article in @jthjournal.bsky.social pubmed.ncbi.nlm.nih.gov/39675564/
pubmed.ncbi.nlm.nih.gov
New targets for antithrombotic medications: seeking to decouple thrombosis from hemostasis - PubMed
Arterial and venous thromboses are the leading causes of morbidity and mortality worldwide. Numerous antithrombotic agents are currently available with antiplatelet, thrombolytic/fibrinolytic, and ant...
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 29/06/2025
Global EHR-based study shows ~6% of children with CHD develop VTE within a year post-surgery, with a 25% recurrence rate. Most cases involved LE-DVT. Highlights need for targeted thromboprophylaxis strategies in this high-risk population. #PedsCardio #Thrombosis www.jthjournal.org/article/S153...
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 24/06/2025
Amazing and thorough discussion on the ISTH Hemophilia Guidelines contents & methodology live at #ISTH2025 See this paper in JTHfor more deconstruction of the guidelines #hemophilia #hemesky www.jthjournal.org/article/S153...
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Marc Carrier, MD @marccarriermd.bsky.social · 23/06/2025
Meta-analysis on GLP-1RA (vs. placebo) and VTE: 🔹 PE rates significantly lower 📉 🔹 VTE rates lower but not statistically significant 🔹 No difference in DVT 🔹 Study design matters: RCTs vs. observational data Accepted for publication in JTH! #ISTH2025 #VTE #GLP1RA #Thrombosis @jthjournal.bsky.social
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International Society on Thrombosis and Haemostasis @isth.org · 23/06/2025
The @rpth.bsky.social and @jthjournal.bsky.social Editors presented the Editors awards this afternoon, including this one to Daniel Steiner.
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 22/06/2025
Corticosteroids remain the go-to for managing transaminitis post-valoctocogene roxaparvovec in hemophilia A. Early, reactive treatment may help preserve FVIII levels. #GeneTherapy #HemophiliaA #HemeSky www.jthjournal.org/article/S153...
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Thita Joy Chiasakul @joythitac.bsky.social · 21/06/2025
Considerations for use of generative AI in publication presented at the Publication Session #ISTH2025 @jthjournal.bsky.social
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RPTH @rpth.bsky.social · 21/06/2025
Find the @rpth.bsky.social and @jthjournal.bsky.social editors in PUB01 - The evolving landscape of academic publishing! 📍Room 151 A&B ⏰ 10:30-11:30 🗣️ @profmakris.bsky.social, Ton Lisman and Suzanne Cannegieter with host Donna DiMichele
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 21/06/2025
🩺 In the PAUSE-2 pilot trial, perioperative management of DOACs in patients undergoing high-bleed-risk surgery or neuraxial procedures was found feasible. Both ASRA- and PAUSE-based strategies achieved similar pre-op DOAC levels, supporting a larger trial. www.jthjournal.org/article/S153...
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Thomas Reiser @tomreiser.bsky.social · 19/06/2025
Just in time for the #ISTH2025 congress! @ISTH.org releases its Updated Clinical Practice Guidelines on the Diagnosis and Treatment of TTP. Learn more ⬇️and if you are attending #ISTH2025, don't miss the Guidelines Session GG01 on Saturday at 09:30 (US ET) bit.ly/3G8zaUp
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 19/06/2025
Blocking tubulin detyrosination via VASH1-SVBP inhibition enhances proplatelet formation & boosts platelet counts—no impact on function. A novel understanding of the megakaryocyte tubulin code beyond tubulin isotypes. #Platelet #HemeSky www.jthjournal.org/article/S153...
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 18/06/2025
What are the barriers to recruitment and participation in RCTs evaluating postpartum thromboprophylaxis? This qualitative study reveals trust in providers, altruism, and risk perception as key motivators and barriers. Important insights for future trial design. www.jthjournal.org/article/S153...
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 15/06/2025
How should women with AT deficiency be managed during pregnancy? This multicenter study shows that high-dose LMWH and peripartum AT concentrate may reduce venous thrombosis risk. www.jthjournal.org/article/S153...
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 13/06/2025
New study uncovers a zebrafish-specific interaction between TPO receptor (zTpoR) and Mapk14a (p38 MAPKα), crucial for thrombocyte development. This direct interaction, absent in humans, regulates thrombocyte count and clotting via unique signaling. #zebrafish www.jthjournal.org/article/S153...
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 11/06/2025
Explore the #June2025 issue of JTH! Highlights: cancer-linked SVT, GPVI malfunction in young platelets, DOAC failure in VTE, and device-induced thrombosis insights. 🩸 jthjournal.org #VTE #hematology
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 30/05/2025
New data reveal a prothrombotic shift in cirrhosis: despite reduced plasmin generation, thrombin generation remains intact—creating a disbalance between coagulation and fibrinolysis. TG/PG ratio may be a novel marker of thrombotic risk. #cirrhosis #thrombosis www.jthjournal.org/article/S153...
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VTE Specialist Network @vsnuk1.bsky.social · 19/05/2025
And a bonus one too 🤗
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 28/05/2025
🩸 In NSCLC patients starting chemo, elevated FXIa:AT and TAT levels predict VTE and mortality. A new biomarker-based score stratifies risk, offering a potential tool for early intervention. #NSCLC #VTE #oncology #thrombosis #HemeSky www.jthjournal.org/article/S153...
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 27/05/2025
🧪 New findings challenge assumptions about young platelets: during stress thrombopoiesis, newly formed platelets show a transient defect in GPVI signaling. Full function appears to develop only after circulation time. #platelets #GPVI #hematology
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 22/05/2025
🧪 Real-world study validates a new ADAMTS-13 assay: fast, reliable, and accurate for diagnosing and monitoring TTP. Strong performance at critical low activity levels makes it a valuable tool in clinical practice. #TTP #hematology #ADAMTS13 #labmedicine #MedSky www.jthjournal.org/article/S153...
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 21/05/2025
🧪 This study uncovers a novel aging-related thrombosis mechanism: Rpl13a snoRNAs in red blood cells drive ROS and venous thrombosis by silencing peroxidasin via 2ʹ-O-methylation. Knocking out these snoRNAs reduced thrombi in aged mice. #thrombosis #hematology www.jthjournal.org/article/S153...
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 20/05/2025
New insights into antiphospholipid syndrome: plasmin cleavage transforms β2GPI into a novel S-shape, increasing exposure to autoantibodies. This structural shift may explain enhanced immune reactivity and altered function. #APS #MedSky
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 18/05/2025
⚠️ ISTH-SSC communication alert: Oral FXa inhibitors can interfere with heparin anti-Xa monitoring during therapy transitions. This may mislead anticoagulation management. This communication offers practical steps for UFH use. #anticoagulation www.jthjournal.org/article/S153...
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 17/05/2025
🫀 This recent review article explores why thrombosis remains a major challenge in mechanical circulatory support. Device surface properties & flow dynamics drive clot risk—offering opportunities for safer designs. #biomaterials #cardiology www.jthjournal.org/article/S153...
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 15/05/2025
In Impella-supported cardiogenic shock, discrepancies between anti-Xa and APTT during UFH therapy are common and linked to higher mortality—especially when paired with abnormal INR or low fibrinogen. #MedSky #Criticalcare #HemeSky www.jthjournal.org/article/S153...
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International Society on Thrombosis and Haemostasis @isth.org · 14/05/2025
For the first time in 16 years, ISTH is returning to the U.S. for an in-person Congress. As we prepare to welcome the world to Washington, D.C., we’re guided by our mission & appreciation for our community🌍 Read more @jthjournal.bsky.social: www.jthjournal.org/article/S1538-7836(25)00213-2/abstract
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 14/05/2025
🧠 New network meta-analysis of 10,665 patients suggests dual antiplatelet therapy (aspirin + clopidogrel) may be the best option for minor stroke—more effective than aspirin or rt-PA, with lower bleeding and mortality risk. #stroke #neurology #DAPT #MedSky www.jthjournal.org/article/S153...
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Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 13/05/2025
Are platelet antibodies clinically relevant? This large cohort study shows that anti-GPIIb/IIIa or anti-GPIb/IX antibodies is associated with lower platelet counts, especially when multiple GPs were targeted or antibody levels were high. #ITP #hematology #MedSky #platelets
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