Adults in the United States reported cannabis use at or near record highs in 2025, reflecting a years-long climb.

This survey study reports on how US adolescents perceive risk related to different levels of fentanyl use.

Recent expansion of U.S. nicotine pouch marketing may increase nicotine pouch use. This study estimated U.S. adult pouch use during 2023–2024 overall …

Objective: Simultaneous alcohol and cannabis use (commonly referred to as SAM) represents a significant public health concern for young adults. Romantic partners are a strong source of influence on su...

Teens in disadvantaged neighborhoods are more likely to smoke, but it depends on whether they live in rural or urban areas.

Objective: We examined associations between neighborhood socioeconomic context and substance use among U.S. adolescents using nationally representative samples. We further tested whether these associations differed by urbanicity. Methods: Data were from 12th graders in 2016–2019 from the Monitoring the Future (MTF) study (n=54,108). Neighborhood socioeconomic context was measured by a disadvantage index in the zipcode of the schools MTF respondents attended, using data on residents’ economic status (income, public assistance, poverty) from the American Community Survey. Outcomes included past 30-day cigarette use, past 2-week binge drinking, and past 30-day cannabis use. Survey-weighted logistic models estimated associations between neighborhood disadvantage and the use of each substance, as well as interactions of the associations by urbanicity (urban, suburban, rural). Results: Neighborhood disadvantage was positively associated with adolescent cigarette use but inversely associated with binge drinking. After controlling for individual-level socioeconomic characteristics, the association between neighborhood disadvantage and adolescent binge drinking became non-significant. The associations of neighborhood disadvantage with cigarette use differed by urbanicity. In rural areas, adolescent cigarette use increased with greater neighborhood disadvantage, which was not observed in urban areas. No significant interaction effects were found for binge drinking and cannabis use. Conclusions: We found a complex interplay between neighborhood socioeconomic context and adolescent substance use, with patterns varying by both urbanicity and substance. This suggests the potential for tailored prevention and intervention efforts for adolescent substance use in particular neighborhood contexts.

Young adults who heavily use substances may report significantly poorer memory decades later, a new University of Michigan study suggests.

Introduction This paper aimed to determine the prevalence, demographic correlates and co-occurring substance use patterns of hallucinogen microdosing among young adults in the United States. Metho...

Background Depression, loneliness and other psychological distress symptoms are common in the US; lifetime cumulative estimates and life course prospective persistence is under-studied. We use nationa...

Objective: Using a national U.S. underage young adult sample, we examined the prevalence of smoking, vaping, eating, drinking, and dabbing cannabis; perceived accessibility by product type; and percei...

This study provides national data on cannabis use type (medical versus recreational only) across individuals aged 19–65 years and associations with ov…

Abstention from drug use remains at historic high, NIH-supported survey finds.

Experts warn doing so may worsen sleep quality and raise the risk for substance abuse over time.

This survey study identifies the prevalence of and demographic characteristics associated with use of substances for sleep purposes in US adults aged 19 to 30 years.

More than 1 in 5 young adults reported using cannabis or alcohol to help them fall asleep.

The percentage of young and midlife adults using nicotine pouches significantly increased last year, while cannabis use, vaping and the use of psychedelic drugs are at or near all-time highs, accordin...

Objective: Using a national U.S. underage young adult sample, we examined prevalence of smoking, vaping, eating, drinking, and dabbing cannabis; perceived accessibility by product type; and perceived ...

The Summer Program offers excellent opportunities for training in research design, analytic strategies, statistical methods, and data management.

The lawsuit says that NIH has canceled more than 670 research grants, which were due more than $1.1 billion in funding.

Among Monitoring the Future Panel study participants aged 35–60 in 2022, midlife alcohol use was generally higher among respondents aged 35–40 (vs. older), males (vs. females), White respondents (vs.....

National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.