mcw44.bsky.social @mcw44.bsky.social · 24/02/2026Even after a rare disease diagnosis, understanding the specific gene variant can help guide care decisions and connect with clinical studies focused on specific genetic changes. Clear, accurate genetic information empowers more informed choices. 000
mcw44.bsky.social @mcw44.bsky.social · 09/01/2026#JPMWeek always sharpens the focus on what matters next. I’m excited to join this live conversation about how new genetic modalities move from powerful ideas to real medicines, and what it takes to push the field forward with ambition and conviction. 000
mcw44.bsky.social @mcw44.bsky.social · 05/01/2026As a rare disease mom, I know how much it matters when progress starts to feel real. In 2025, Alltrna took big leaps to advance our first #tRNA medicine towards the clinic. I’m deeply proud of this team and energized by what lies ahead! 020
mcw44.bsky.social @mcw44.bsky.social · 19/12/2025Grateful for the @Alltrna team and the way you care for one another while pushing this work forward. Giving back together and taking time to celebrate means a lot. Wishing all a joyful and healthy holiday season. 010
mcw44.bsky.social @mcw44.bsky.social · 03/12/2025The PKU community brings strength, insight, and a deep commitment to supporting one another, and today is an important moment to recognize that. I am thankful for the National PKU Alliance, who continues to bring forward important resources. 010
mcw44.bsky.social @mcw44.bsky.social · 24/11/2025To everyone at @Alltrna, thank you for your passion, your focus on patients, and the way you collaborate and support one another. Every voice, every experience, and every thoughtful risk moves our mission forward. You are Alltrna, and I am deeply grateful for all that you do! 010
mcw44.bsky.social @mcw44.bsky.social · 07/10/2025As both a parent and a leader, I know firsthand the joys and challenges of balancing family and work. I believe these experiences deserve recognition, support, and celebration, and I I am grateful that @Alltrna fosters such opportunities to learn from each other and grow together. 000
Reposted by @mcw44.bsky.socialAlltrna @alltrna.bsky.social · 30/09/202595% of genetic #rarediseases lack therapies. On #InternationalPodcastDay, Alltrna CEO @mcw44.bsky.social shares how engineered #tRNA medicines can restore protein production and uniquely treat many diseases with the same underlying mutation. bit.ly/3VR6LXd #RNAsky #StopCodonDisease 041
mcw44.bsky.social @mcw44.bsky.social · 25/09/2025The first 25 years of @Flagship Pioneering have proven the power of bold ideas to change medicine. The next 25 are about Bigger Leaps—taking on the greatest challenges in science so that no patient, with a rare or common disease, is left without the chance at a breakthrough. 010
mcw44.bsky.social @mcw44.bsky.social · 08/09/2025Thanks @Drug Target Review for spotlighting Alltrna’s approach to broadening the reach of genetic medicines. We need to move beyond one-disease, one-drug thinking and #tRNA therapeutics can help us address the severe unmet need in rare and ultra-rare diseases. #RNAsky 010
mcw44.bsky.social @mcw44.bsky.social · 28/07/2025Proud to work alongside a team that centers accessibility – not as a task, but as a value. We honor #DisabilityPrideMonth by continuing to build a culture where every voice and experience is valued. #WeAreAlltrna #Inclusion 000
mcw44.bsky.social @mcw44.bsky.social · 22/07/2025The finale to the conversation I had with Anna Rose Welch! This second article dives into how we’re translating the potential of #tRNA into patient impact—scientifically, strategically, and personally. Part 2 below. Part 1 here: bit.ly/3RNGuar Thanks for following the journey. #RNAskybit.ly"Raiders Of The Lost Codon:" Alltrna On Evolving "Ancient" tRNA Into Therapeutics<p>Here, in part one of this two-part article, we identify how tRNA stands apart from other RNA modalities and gene therapies, as well as how this molecule’s unique “skill set” is guiding the company’s future clinical strategy.</p> 010
mcw44.bsky.social @mcw44.bsky.social · 19/06/2025Thank you for an incredible discussion on next-gen advocacy in rare disease at #BIO2025. Real change takes all of us – patients, families, regulators, industry – pushing forward together. #RNAsky #rarediseases 021
mcw44.bsky.social @mcw44.bsky.social · 12/06/2025A special conversation that brings together the personal and the scientific. Thank you, @grinsteinj.bsky.social cial, for the space to share my and @alltrna.bsky.social ial’s story on the 𝘽𝙚𝙝𝙞𝙣𝙙 𝙩𝙝𝙚 𝘽𝙧𝙚𝙖𝙠𝙩𝙝𝙧𝙤𝙪𝙜𝙝𝙨 podcast. 000
mcw44.bsky.social @mcw44.bsky.social · 09/06/2025When my son was diagnosed with #Duchenne, patient groups helped me find my way — and today, patients and families continue to inspire my work at @alltrna.bsky.social. In this @Science.org webinar, I share what I learned when my personal and professional journeys converged. 010
mcw44.bsky.social @mcw44.bsky.social · 03/06/2025Advocacy is not just about raising awareness – it’s driving the science forward. I am proud to join incredible voices at #BIO2025 to explore how patients and families are accelerating innovation in rare disease drug development. 010
mcw44.bsky.social @mcw44.bsky.social · 29/05/2025I truly appreciated the opportunity to share my story and our work at @alltrna.bsky.social with @benmcomer.bsky.social, Anna Rose Welch, and Matthew Pillar for the Business of Biotech podcast. Thanks for the great conversation! 000
Reposted by @mcw44.bsky.socialAlltrna @alltrna.bsky.social · 27/05/2025We’ve been walking together this May for #MoveYourPheet, in support of the National PKU Alliance—raising awareness for PKU and connecting as a team. These moments remind us why our work matters. 💚 Learn more: secure.qgiv.com/event/moveyo... #PKUAwareness #PKUAwarenessMonth #RareDisease 021
Reposted by @mcw44.bsky.socialAlltrna @alltrna.bsky.social · 20/05/2025𝟵𝟱% 𝗼𝗳 𝗿𝗮𝗿𝗲 𝗱𝗶𝘀𝗲𝗮𝘀𝗲𝘀 𝗵𝗮𝘃𝗲 𝗻𝗼 𝗙𝗗𝗔-𝗮𝗽𝗽𝗿𝗼𝘃𝗲𝗱 𝘁𝗵𝗲𝗿𝗮𝗽𝘆. Alltrna’s engineered tRNAs enable a mutation-first approach—and open the door to basket clinical trials across diseases. @mcw44.bsky.social shares more: bit.ly/3GUXNUx #ClinicalTrialsDaybit.lyAlltrna plans to tackle rare diseases using tRNA-based therapies - Pharmaceutical TechnologyAlltrna’s CEO Michelle Warner said that the approach allows for basket trials that can group patients with different diseases together. 031
mcw44.bsky.social @mcw44.bsky.social · 15/05/2025As a mom to a child with Duchenne, I am especially honored for @alltrna.bsky.social to present at @cureduchenne.bsky.social #FUTURES2025. We are sharing early work on engineered tRNA medicines and their potential to address nonsense mutations in Duchenne. 020
mcw44.bsky.social @mcw44.bsky.social · 12/05/2025Honored to deliver the 𝗦𝘁𝗮𝘁𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗔𝗿𝘁 𝗟𝗲𝗰𝘁𝘂𝗿𝗲 at #ASCPT2025. Being a parent to a child with Duchenne has shaped my belief that empathy and urgency must guide how we transform drug development for rare diseases. #PatientCentricity #BiotechLeadership 020
mcw44.bsky.social @mcw44.bsky.social · 07/05/2025Loved this thoughtful—and adventurous—take on the promise of #tRNA. Thank you to Anna Rose Welch for the great conversation and for capturing in Part 1 how we at @alltrna.bsky.social are unearthing the therapeutic potential of this ancient molecule to build a new future for patients. 000
mcw44.bsky.social @mcw44.bsky.social · 01/05/2025Alltrna is proud to support #MoveYourPheet for #PKUAwarenessMonth, an initiative led by the National PKU Alliance. I’m honored to walk alongside this community and to help drive the development of new therapeutics that aim to change the trajectory of PKU and other rare diseases. 010
mcw44.bsky.social @mcw44.bsky.social · 22/04/2025Thank you to @dikaojiakor.bsky.social for covering our work at @alltrna.bsky.social and the promise of AP003—our lead tRNA therapeutic candidate moving toward the clinic. 000
mcw44.bsky.social @mcw44.bsky.social · 08/04/2025My son’s diagnosis shook my world – but clarified my purpose. As rare disease drug development faces real headwinds, we can’t slow down. We need faster, scalable innovation – and to raise our voices to keep rare disease a priority. 000
mcw44.bsky.social @mcw44.bsky.social · 07/04/2025At @alltrna.bsky.social, we’re pioneering a new approach to medicine with tRNA–driven by science and inspired by patients. I shared more about my journey and purpose with BioSpace. 000
mcw44.bsky.social @mcw44.bsky.social · 25/03/2025Developing personalized medicines is critical for tackling rare diseases, but pursuing a one-drug-per-disease paradigm for the 6,000+ rare genetic conditions is an untenable strategy. Nerissa, Alltrna’s CMO, explains our novel way of addressing this challenge by leveraging tRNA’s unique biology. 000
Reposted by @mcw44.bsky.socialAlltrna @alltrna.bsky.social · 17/03/2025tRNA therapeutics may help restore full-length proteins in muscle #StopCodonDisease. At @mda.org's Annual Conference, Stephen Eichhorn will discuss developing engineered #tRNA therapeutics to address premature termination codons in #rarediseases, like #musculardystrophy. www.mdaconference.org 021
mcw44.bsky.social @mcw44.bsky.social · 12/03/2025Honored to participate in the PPMD 2025 Advocacy Conference, where patients, families, researchers, and policymakers unite to advance progress for #Duchenne. Advocacy plays a key role in shaping policy, driving research, and improving access to treatments for #rarediseases. bit.ly/41koLvl 010
mcw44.bsky.social @mcw44.bsky.social · 10/03/2025Rare diseases affect 350M people worldwide, yet 95% have no FDA-approved treatment. We need a bold new approach—and collaboration among all the stakeholders. The time to act is now. I explain more in this editorial for @fortune.com: fortune.com/2025/03/10/r...fortune.comMy son’s rare disease diagnosis spurred me to ditch Big Pharma for a biotech startupMost individuals diagnosed with a rare disease won’t live to become teenagers or adults. I knew what I had to do. 010
Reposted by @mcw44.bsky.socialAlltrna @alltrna.bsky.social · 10/03/2025Looking forward to 𝗢𝗣𝗧 𝗖𝗼𝗻𝗴𝗿𝗲𝘀𝘀 𝟮𝟬𝟮𝟱, where Alltrna CTO William Kiesman will present on designing, manufacturing, and delivering #tRNA therapeutics for #StopCodonDisease. He will also join a breakout discussion on optimizing new RNA modalities as therapeutics. bit.ly/41RGnAe #RNAsky 021
mcw44.bsky.social @mcw44.bsky.social · 28/02/2025Never underestimate the power of patients and their families. They are a real force to be reckoned with, and they have so much valuable insight to impart. I appreciate all of the engagement I have had within the rare disease community over the past few years, both personally and professionally. 000
mcw44.bsky.social @mcw44.bsky.social · 27/02/2025I do think that “cures” exist for many patients living with rare diseases. The technology is out there. We've just got to move it forward, and move it forward with a sense of urgency to really make a difference for these families. 000
mcw44.bsky.social @mcw44.bsky.social · 26/02/2025At Alltrna, we're so invested in our work, because we know we're doing exciting science that could have a very profound impact on patients that's unlike anything else that exists today. 000
mcw44.bsky.social @mcw44.bsky.social · 25/02/2025#RareDiseaseWeek I’ve been excited to see Alltrna's progress in advancing a #tRNA drug candidate that has the potential to restore PAH protein production for those whose PKU is caused by a premature termination codon.rarediseases.org 020
Reposted by @mcw44.bsky.socialAlltrna @alltrna.bsky.social · 25/02/2025#𝗗𝗬𝗞: There are about 400 rare genetic liver diseases? One of them is PKU, a genetic metabolic disorder that prevents the body from properly breaking down phenylalanine, an amino acid found in many foods. Learn more about the condition: www.npkua.org/about-pku/ #RareDiseaseWeek #PKUAwareness 021
