Sign in

Alltrna

@alltrna.bsky.social
111 followers 303 following 64 posts

Alltrna is the world’s first transfer RNA (tRNA) platform company, and we are unlocking the vast therapeutic potential within #tRNA biology. #StopCodonDisease Learn more: www.alltrna.com

PostsRepliesMedia
Alltrna @alltrna.bsky.social · 31/03/2026
Alltrna has received approval to initiate the first clinical trial of a tRNA therapeutic! It's more than a company milestone, it's a first step toward a different model for rare disease drug development, built around shared genetic mutations instead of treating one disease at a time. bit.ly/4tjsuFR
121
Alltrna @alltrna.bsky.social · 23/03/2026
At Alltrna, we know progress is shaped by the people who inspire, support, and lead us. This Women’s History Month, our team is honoring the women who have made a lasting impact on our lives and work by sharing their stories and celebrating their influence.
000
Alltrna @alltrna.bsky.social · 24/02/2026
During #RareDiseaseWeek, we’re highlighting the role of genetic testing. For many families, this is an important next step, even after diagnosis. Knowing the specific gene variant can inform care and open access to clinical studies. Learn more here: bit.ly/3OrFxpQ
120
Alltrna @alltrna.bsky.social · 08/01/2026
If you’re at #JPMWeek, check out Wednesday’s live recording of The Genetics Podcast for a conversation on translating emerging RNA and gene-editing modalities into meaningful patient benefit, featuring Alltrna CEO @mcw44.bsky.social. bit.ly/3YxH8w5 #tRNA #StopCodonDisease #RNAsky #JPM26
020
Alltrna @alltrna.bsky.social · 05/01/2026
2025 was a year of momentum and big leaps at Alltrna. Each step reflected our belief that patients deserve better and our commitment to boldly building a new future for those with Stop Codon Disease. We look forward to 2026 and taking the next meaningful leaps in the clinic.
010
Alltrna @alltrna.bsky.social · 19/12/2025
As the year wraps up, we’re grateful for our Alltrna team and the way they showed up for one another and our community. From our String of Giving donation drive to a little holiday fun together, thank you for an incredible year. Warm holiday wishes from all of us at Alltrna.
010
Alltrna @alltrna.bsky.social · 16/12/2025
From patents to patients. For Nick Triano, protecting innovation in biotech also means making an impact in #raredisease treatment. Meet Alltrna's Senior Legal Counsel in the latest #EmployeeSpotlight posted on www.alltrna.com/life-at-allt.... #WeAreAlltrna
010
Alltrna @alltrna.bsky.social · 03/12/2025
Today is #PKUAwarenessDay. Additional #genetictesting can help people with #PKU understand the variants (aka mutations) behind their disease which can guide care and clarify eligibility for #clinicaltrials. Watch the video from #NPKUA and @nordrare.bsky.social to learn more: bit.ly/48psGe0
020
Alltrna @alltrna.bsky.social · 24/11/2025
This November, we set aside time to reflect, say thank you, and celebrate our team. #Gratitude is not limited to one month for us. It is part of who we are as one team and how we give our best to build a new future for patients every day. #WeAreAlltrna
010
Alltrna @alltrna.bsky.social · 28/10/2025
At the 2nd MENA Congress for Metabolism in Health and Disease 2025, Alltrna highlighted how engineered #tRNA medicines can restore protein synthesis in liver #StopCodonDisease and inborn errors of metabolism. metabolism.ae #RNAsky
010
Alltrna @alltrna.bsky.social · 22/10/2025
Small groups, big impact. Our new Peer Mentoring Circles give colleagues space to share experiences, build skills, and strengthen community. The first session was a success! We’re excited to see how far we go and grow together. #WeAreAlltrna #Mentorship #LifeAtAlltrna
000
Alltrna @alltrna.bsky.social · 09/10/2025
Alltrna CMO Dr. Nerissa Kreher will join leaders from across the #raredisease field for a panel titled, “𝘼 𝙉𝙚𝙬 𝙀𝙧𝙖 𝙛𝙤𝙧 𝙍𝙖𝙧𝙚 𝘿𝙞𝙨𝙚𝙖𝙨𝙚 𝘾𝙡𝙞𝙣𝙞𝙘𝙖𝙡 𝙏𝙧𝙞𝙖𝙡𝙨,” at the 𝗡𝗢𝗥𝗗 𝗥𝗮𝗿𝗲 𝗗𝗶𝘀𝗲𝗮𝘀𝗲𝘀 & 𝗢𝗿𝗽𝗵𝗮𝗻 𝗣𝗿𝗼𝗱𝘂𝗰𝘁𝘀 𝗕𝗿𝗲𝗮𝗸𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝗦𝘂𝗺𝗺𝗶𝘁 in Washington, D.C. #NORDSummit: nordsummit.org @nordrare.bsky.social
010
Alltrna @alltrna.bsky.social · 07/10/2025
Behind every breakthrough at Alltrna are people who are not only scientists, innovators, and colleagues, but also parents and caregivers. For Working Parent Awareness Day, our Culture Team hosted an excellent panel about balancing family life with meaningful work. #NationalWorkingParentsDay
010
Alltrna @alltrna.bsky.social · 30/09/2025
95% of genetic #rarediseases lack therapies. On #InternationalPodcastDay, Alltrna CEO @mcw44.bsky.social shares how engineered #tRNA medicines can restore protein production and uniquely treat many diseases with the same underlying mutation. bit.ly/3VR6LXd #RNAsky #StopCodonDisease
041
Alltrna @alltrna.bsky.social · 25/09/2025
Congrats to our colleagues at Flagship Pioneering on 25 years of turning bold ideas into medicines. At Alltrna, we’re building on this legacy of #BiggerLeaps by pioneering #tRNA medicines to unify treatment across #StopCodonDisease and redefine what’s possible for patients. #FlagshipFounded
010
Alltrna @alltrna.bsky.social · 17/09/2025
For Ayush, science is both an intellectual challenge and a creative pursuit. He has turned his passion into possibility in his role as a research associate at Alltrna, where he explores massive design spaces to find the best tRNAs for therapeutic development. www.alltrna.com/life-at-allt...
020
Alltrna @alltrna.bsky.social · 08/09/2025
Drug Target Review spotlights Alltrna’s mutation-driven strategy to expand the reach of genetic medicine. By focusing on the shared genetic cause, rather than one disease at a time, our tRNA therapeutic approach can accelerate rare disease drug development. bit.ly/4858rUi #StopCodonDisease
drugtargetreview.com
New tRNA tech aims to rewrite rare disease treatment
Explore the role of tRNA in genetic medicine and how Alltrna is revolutionizing therapies for rare genetic diseases.
020
Alltrna @alltrna.bsky.social · 03/09/2025
Alltrna appoints Dave Hava as CSO. With two decades translating breakthrough science into first-in-class drugs, he will expand and prioritize our tRNA medicines pipeline. Grateful to our first CSO Chris Henderson, who will continue to guide our science as our SAB chair. bit.ly/4mPxcbK
020
Alltrna @alltrna.bsky.social · 02/09/2025
We’re pleased to share that Alltrna will present at the International Congress of Inborn Errors of Metabolism (ICIEM 2025), taking place September 2-6 in Kyoto, Japan. For more info: site2.convention.co.jp/iciem2025/we... #ICIEM2025 #RNAsky #StopCodonDisease #rarediseases #tRNA
An image with Nerissa and details of Alltrna's presentation at ICIEM 2025
020
Alltrna @alltrna.bsky.social · 12/08/2025
Alltrna volunteers spent our annual #DayofService with Cradles to Crayons, helping provide essential items to children living in low-income and homeless situations. Proud to support their mission to #EndClothingInsecurity, www.cradlestocrayons.org. #WeAreAlltrna
010
Alltrna @alltrna.bsky.social · 04/08/2025
For #RNADay, we’re spotlighting the therapeutic potential of #tRNA to move beyond the one-gene, one-disease, one-drug paradigm and scale genetic medicine for thousands of rare diseases. Learn more: www.alltrna.com/trna-biology #RNAsky #WorldRNADay
000
Alltrna @alltrna.bsky.social · 28/07/2025
July is #DisabilityPrideMonth, reminding us that disability is a natural and valuable part of human diversity. At Alltrna, accessibility is not a project – it is woven into our values. We are one team, embracing all voices and experiences as we advance tRNA therapeutics for patients. #WeAreAlltrna
Image: Disability Pride Flag
Use: Symbol of the Disability community and the Disability Pride Movement
Description: A charcoal grey flag bisected diagonally from the top left corner to the lower right corner by five parallel stripes in red, pale gold, pale grey, light blue, and green. Designed to be visually safe and inclusive. Designed by Ann Magill and adopted into use in 2021.
020
Alltrna @alltrna.bsky.social · 24/07/2025
Earlier this month we took a moment collectively to recharge, so we could return to work with fresh perspectives. At Alltrna, curiosity sparks discovery, and time away helps us thrive. When we reunite, we’re one team, committed to giving it our all for patients everywhere. #WeAreAlltrna
010
Alltrna @alltrna.bsky.social · 22/07/2025
Raiders of the Lost Codon Part 2: The Hunt Continues. In this new Advancing RNA article, Alltrna CEO @mcw44.bsky.social 4.bsky.social shares how we’re navigating the scientific and strategic challenges of bringing our first #tRNA medicines to patients. bit.ly/451yuc7 #StopCodonDisease #RNAsky
advancingrna.com
Ancient Molecule, Modern Medicine: The Science, Strategy, & Stakeholders Behind tRNA Therapeutics
<p>As we all know well, &ldquo;unearthing&rdquo; our molecules&rsquo; potential poses numerous technical and business-related challenges for young biotech companies. Here, Werner and I continue our conversation, unpacking some of these internal and external challenges the company is navigating as it strives to bring tRNA to the commercial market.</p>
020
Alltrna @alltrna.bsky.social · 15/07/2025
At the Propionic Acidemia Conference, we presented about how premature stop codons cause #rarediseases, like PA, and the need for #genetictesting, even after a diagnosis. If you missed it, you can learn more about #tRNA therapeutics and #StopCodonDisease here: www.alltrna.com/stop-codon-d....
000
Alltrna @alltrna.bsky.social · 30/06/2025
For #PrideMonth2025, Alltrna is reading and discussing The House in the Cerulean Sea by TJ Klune. It’s a beautiful story about identity and belonging. We also gathered for a Pride happy hour to connect and reflect on what inclusion and belonging mean to each of us. #WeAreAlltrna #PrideMonth
010
Alltrna @alltrna.bsky.social · 26/06/2025
Joyner Eke’s job is about more than engineering a molecule – it’s about building a future where more families have more time. Her work in process development and purification is critical to scaling Alltrna’s #tRNA medicines. Watch her video here: www.alltrna.com/life-at-allt... #StopCodonDisease
010
Alltrna @alltrna.bsky.social · 25/06/2025
Alltrna scientists presented at #RNA25 and the 2025 IRSF #RettSyndrome Scientific Meeting on our advancement of #tRNA as a new therapeutic modality to treat diseases caused by the same underlying mutation. Thanks to our team for their outstanding work! #StopCodonDisease #RNAsky
020
Reposted by Alltrna
mcw44.bsky.social @mcw44.bsky.social · 19/06/2025
Thank you for an incredible discussion on next-gen advocacy in rare disease at #BIO2025. Real change takes all of us – patients, families, regulators, industry – pushing forward together. #RNAsky #rarediseases
021
Alltrna @alltrna.bsky.social · 17/06/2025
Don't forget -- our panel is today at 1:45pm ET in Room 251! #BIO2025
000
Alltrna @alltrna.bsky.social · 12/06/2025
On Behind the Breakthroughs #podcast, Alltrna CEO @mcw44.bsky.social shares how personal experience drives our mission – and how engineered tRNAs could unlock new treatments for diseases caused by premature stop codons. Read the Q&A & listen here: bit.ly/4mZWjZN #tRNA #StopCodonDisease #RNAsky
030
Alltrna @alltrna.bsky.social · 10/06/2025
Congratulations to Sandra Visser, Ph.D., SVP, Head of Therapeutics Development at Alltrna, on being named President of @ascptclinpharm.bsky.social for 2025-2026! We’re proud to see her leadership recognized by the clinical pharmacology community. #ASCPT2025 #PatientCentricity
010
Alltrna @alltrna.bsky.social · 09/06/2025
When @mcw44.bsky.social's son was diagnosed with #Duchenne, patient groups became a lifeline. In this @science.org webinar, she shares how that shaped her leadership at Alltrna, listening to families as we develop #tRNA medicines to treat #StopCodonDisease. www.science.org/content/webi... #RNAsky
science.org
Bright breakthroughs: Real stories of beating rare disease
010
Alltrna @alltrna.bsky.social · 06/06/2025
In the BioPharm International feature on 𝙉𝙚𝙭𝙩 𝙂𝙚𝙣𝙚𝙧𝙖𝙩𝙞𝙤𝙣 𝘽𝙞𝙤𝙩𝙝𝙚𝙧𝙖𝙥𝙚𝙪𝙩𝙞𝙘𝙨, Sandra shares how engineered tRNAs represent a fundamentally different disease-agnostic approach with the potential to treat thousands of rare and ultra-rare conditions. #RNAsky www.biopharminternational.com/view/next-ge...
010
Alltrna @alltrna.bsky.social · 03/06/2025
Patients and families are driving innovation in rare disease. At #BIO2025, @mcw44.bsky.social joins a panel of champions to explore how next-gen advocacy is accelerating science and transforming how we develop and deliver new medicines. #RNAsky
020
Alltrna @alltrna.bsky.social · 29/05/2025
A rare disease diagnosis in her own family pushed @mcw44.bsky.social to rethink her career. On the Business of Biotech podcast, she shares what brought her to Alltrna, and why engineered tRNAs may redefine what’s possible in medicine. 🎧 Listen here: www.lifescienceleader.com/doc/leading-...
010
Alltrna @alltrna.bsky.social · 27/05/2025
We’ve been walking together this May for #MoveYourPheet, in support of the National PKU Alliance—raising awareness for PKU and connecting as a team. These moments remind us why our work matters. 💚 Learn more: secure.qgiv.com/event/moveyo... #PKUAwareness #PKUAwarenessMonth #RareDisease
021
Reposted by Alltrna
American Society of Clinical Pharmacology & Therapeutics @ascptclinpharm.bsky.social · 19/05/2025
With State of the Art and Featured Speakers like Michelle Werner of Alltrna (@alltrna.bsky.social), Colin Pillai of CP+ Associates and Pharmacometrics Africa, and Brian Corrigan of Metrum RG, #ASCPT2025 is jam-packed with exciting scientific content! bit.ly/3Hb77nq
011
Alltrna @alltrna.bsky.social · 22/05/2025
We’ve moved! Alltrna is now in our new labs and offices – a space for bold science and big ideas. Here's to the next chapter in pioneering tRNA therapeutics and building a new future for patients. www.alltrna.com/life-at-allt...
010
Alltrna @alltrna.bsky.social · 20/05/2025
𝟵𝟱% 𝗼𝗳 𝗿𝗮𝗿𝗲 𝗱𝗶𝘀𝗲𝗮𝘀𝗲𝘀 𝗵𝗮𝘃𝗲 𝗻𝗼 𝗙𝗗𝗔-𝗮𝗽𝗽𝗿𝗼𝘃𝗲𝗱 𝘁𝗵𝗲𝗿𝗮𝗽𝘆. Alltrna’s engineered tRNAs enable a mutation-first approach—and open the door to basket clinical trials across diseases. @mcw44.bsky.social shares more: bit.ly/3GUXNUx #ClinicalTrialsDay
bit.ly
Alltrna plans to tackle rare diseases using tRNA-based therapies - Pharmaceutical Technology
Alltrna’s CEO Michelle Warner said that the approach allows for basket trials that can group patients with different diseases together.
031
Alltrna @alltrna.bsky.social · 15/05/2025
Alltrna will be at @cureduchenne.bsky.social's #FUTURES2025 to present on how engineered tRNA medicines may uniquely overcome nonsense mutations—also called premature termination codons—in #Duchenne, with the goal of restoring full-length dystrophin. #StopCodonDisease #RNAsky
010
Alltrna @alltrna.bsky.social · 12/05/2025
Proud to share that @mcw44.bsky.social is delivering the 𝗦𝘁𝗮𝘁𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗔𝗿𝘁 𝗟𝗲𝗰𝘁𝘂𝗿𝗲 at #ASCPT2025! Her talk will spotlight how empathy and innovation can transform #raredisease #drugdevelopment. @ascptclinpharm.bsky.social: bit.ly/3F4XyWt #tRNA #StopCodonDisease #RNAsky #PatientCentricity
021
Alltrna @alltrna.bsky.social · 07/05/2025
𝙍𝙖𝙞𝙙𝙚𝙧𝙨 𝙤𝙛 𝙩𝙝𝙚 𝙇𝙤𝙨𝙩 𝘾𝙤𝙙𝙤𝙣? #tRNA may be ancient, but its therapeutic future is just beginning. In this new article, Alltrna CEO @mcw44.bsky.social shares how we’re using tRNA’s universal biology to potentially treat many diseases. bit.ly/3RNGuar #StopCodonDisease #RNAsky
bit.ly
"Raiders Of The Lost Codon:" Alltrna On Evolving "Ancient" tRNA Into Therapeutics
<p>Here, in part one of this two-part article, we identify how tRNA stands apart from other RNA modalities and gene therapies, as well as how this molecule&rsquo;s unique &ldquo;skill set&rdquo; is gu...
031
Alltrna @alltrna.bsky.social · 05/05/2025
Alltrna’s presentation at #TIDESUSA will highlight preclinical data supporting the potential of #tRNA therapeutics to restore full-length protein synthesis in diseases caused by premature termination codons. #StopCodonDisease #BIOsky #RNAsky
010
Alltrna @alltrna.bsky.social · 01/05/2025
It’s #PKUAwarenessMonth, and Alltrna is proud to support #MoveYourPheet, an event benefiting the National PKU Alliance. We’re walking together to raise awareness for PKU and the need for continued innovation in care. Learn more: secure.qgiv.com/event/moveyo... #PKUAwareness #RareDisease
031
Alltrna @alltrna.bsky.social · 22/04/2025
tRNA is emerging as a powerful new therapeutic approach for #rarediseases. Drug Discovery News highlights how Alltrna is advancing #tRNA medicines to restore protein function across many diseases. Read the article here: bit.ly/3QYlH3o #StopCodonDisease
010
Alltrna @alltrna.bsky.social · 15/04/2025
Proud to see Alltrna scientists sharing their work at two Gordon Research Conferences! We’re honored to contribute to the scientific dialogue driving forward innovation in #tRNA therapeutics. #StopCodonDisease
010
Alltrna @alltrna.bsky.social · 08/04/2025
“Every single day matters.” As FDA layoffs & Priority Review Voucher program uncertainty challenge rare disease drug development, Alltrna CEO @mcw44.bsky.social shares why we need speed, scale & access now more than ever. Read more in PharmaVoice: bit.ly/3RDgNsO
bit.ly
Her son’s DMD diagnosis shook her world. As a biotech CEO, it was also an epiphany for better rare disease R&D.
Five years ago, Michelle Werner received her son’s Duchenne muscular dystrophy diagnosis with fear and desperation. Now, as CEO of Alltrna, she’s finding better ways to develop treatments.
010
Alltrna @alltrna.bsky.social · 07/04/2025
At Alltrna, we believe tRNA is key to unlocking new possibilities in medicine. In this BioSpace feature, our CEO @mcw44.bsky.social shares what drives her–and why our work could build a new future for patients. bit.ly/3E7SOyX #tRNA #StopCodonDisease #rarediseases
010
Alltrna @alltrna.bsky.social · 02/04/2025
At The CMO Summit 360º next week, Alltrna CMO Dr. Nerissa Kreher will moderate the 𝗖𝗠𝗢 𝗠𝗲𝗻𝘁𝗼𝗿𝘀𝗵𝗶𝗽 𝗧𝗼𝘄𝗻 𝗛𝗮𝗹𝗹 – exploring topics from career growth to the challenges and opportunities shaping biotech today. cmosummit360.com
000