iiinova — where your digital self keeps evolving

Jonathan D. Grinstein @grinsteinj.bsky.social · 23/09/2026

Can someone explain the GRAIL/WSJ/FDA controversy? I have found that there are opposing stances on whether it’s useful/applicable or not? Do the papers that came out hours ago in Nature Medicine and NEMJ change anything since the data had already been disclosed?

000

Jonathan D. Grinstein @grinsteinj.bsky.social · 19/05/2026

Hoping the FBI doesn’t show up at my door in response to my deep dive into the culling of FDA leadership, focusing on Makary’s resignation and the blocked publication of two COVID-19 vaccine safety studies accepted in medical journals. www.insideprecisionmedicine.com/topics/trans...

insideprecisionmedicine.com

Reporter’s Notebook: The Day the Scientific Debate Died

By the time FDA Commissioner Makary resigned, vaccine safety disputes had become a fight over scientific authority and public dissent.

010

Jonathan D. Grinstein @grinsteinj.bsky.social · 25/02/2026

In this Behind the Breakthroughs episode, @ayzhou.bsky.social argues that nonprofits play a unique role: funding shared infrastructure, driving standardization, and enabling collaboration at scale. Apple Podcasts link: tinyurl.com/IPMsBTBonAP Spotify link: tinyurl.com/IPMsBTBonSpo...

000

Jonathan D. Grinstein @grinsteinj.bsky.social · 30/10/2025

Shana Kelley, PhD, President of the Chan Zuckerberg (@chanzuckerberg.bsky.social) Biohub Chicago, is advancing “instrumented tissues” to precisely measure biological processes. Learn more about her groundbreaking work on this episode of Behind the Breakthroughs. tinyurl.com/3betkes4

insideprecisionmedicine.com

Shana Kelley: Instrumented Tissues for Monitoring Human Body in Real-Time

The director at the Chan Zuckerberg Biohub Chicago shares how researchers are paving the way for implanted diagnostics for inflammation and more.

000

Jonathan D. Grinstein @grinsteinj.bsky.social · 21/08/2025

Hear David Liu share his approach/philosophy to solving biological problems on IPM's BTB podcast Apple podcast link: itunes.apple.com/us/podcast/i... Spotify link: open.spotify.com/show/03X80PT... Acast: shows.acast.com/67105af84872... @broadinstitute.bsky.social @harvard.edu @broadinstitute.org

021

Jonathan D. Grinstein @grinsteinj.bsky.social · 20/08/2025

SEEKING TESTIMONIALS ON PERSONAL GENOMIC TESTING FOR MAGAZINE SERIES If you’ve done DTC (e.g., Nucleus Genomics) or clinician initiated testing and want to share your experience (good or bad) or questions/concerns, DM or email me. Here’s part 1: www.insideprecisionmedicine.com/topics/preci...

insideprecisionmedicine.com

My Personal Genomics Journey in 23andMe’s Resurrection Era

This three-part series examines the current paths for sequencing, analyzing, and utilizing an individual’s genome to guide healthcare decisions.

010

Jonathan D. Grinstein @grinsteinj.bsky.social · 14/07/2025

On Thursday, the NIH dropped 2 news bombs: ending funding for animal-only research to prioritize human studies & publishing more >200 complete response letters to FDA applications for drugs/biologics during 2020-2024. I want to hear your thoughts! DM, post, email... @altnih4science.bsky.social

100

Jonathan D. Grinstein @grinsteinj.bsky.social · 09/07/2025

Mike Previte, Element Biosciences cofounder/CTO, is (Good) Will Hunting IRL. Check out Mike discuss why and how he's developing tools like 5D single-cell multiomics in the latest IPM "Behind The Breakthroughs" episode out now! @elembio.bsky.social @sagepub.com shows.acast.com/67105af84872...

shows.acast.com

More than a Feeling: Predicting Biology with Spatiotemporal Multiomics | Behind the Breakthroughs

Mike Previte, PhD [Element Biosciences]

000

Jonathan D. Grinstein @grinsteinj.bsky.social · 05/02/2025

In this episode, cell therapy expert Katy Rezvani, MD, PhD, (@mdanderson.bsky.social) tells me why she loves NK cells & the ways they’re being engineered to treat cancer and other diseases as accessible and affordable cell tx. shows.acast.com/67105af84872...

shows.acast.com

Allogeneic NK Cells Are Coming to Beat Cancer at a Clinic Near You | Behind the Breakthroughs

Katy Rezvani, MD, PhD [MD Anderson Cancer Center]

020

Reposted by Jonathan D. Grinstein

Kumail Nanjiani @kumail.bsky.social · 09/01/2025

Have been on Bluesky quite a bit the last two days (for info & resources) & it’s not social media that’s broken. I think it’s us that’s broken now. I’ll post about places ppl can donate because LA is in bad shape & my replies are full of “ummmm sounds like somebody’s never heard of Pompeii.”

1249260741933

Jonathan D. Grinstein @grinsteinj.bsky.social · 04/12/2024

Obligatory “Hello World.” 1: I think it’s amazing that @bsky.app took twitter’s colors and chose a metamorphosed flying creature. 2: If you haven't heard what NVIDIA is doing in R&D and healthcare, it's time you find out. Check out the latest episode of my podcast: shows.acast.com/67105af84872...

shows.acast.com

Carrying Medicine Into the Post-Moore’s Law Era | Behind the Breakthroughs

Harry Clifford, PhD [NVIDIA]

031