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Marjan Ghotbi

@marjanghotbi.bsky.social
64 followers 97 following 10 posts

Lifelong learner exploring microbial ecology, microbiomes, microbe–microbe and host–microbe interactions. @ GEOMAR Helmholtz Centre for Ocean Research | @ Kiel University

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Reposted by Marjan Ghotbi
George Bouras @gbouras13.bsky.social · 07/08/2026
If you are looking for web-based phage annotation, phage-annotation.org is live. Upload a genome to run Pharokka, Phold and Phynteny sequentially (see our recent protocols paper doi.org/10.1002/cpz1...). If you have feedback, please reach out Thanks to @ardc.edu.au for making this possible!
phage-annotation.org
Phage Annotation Server -- phage genome annotation
Free automated phage genome annotation -- pharokka, phold and phynteny in one pipeline.
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Reposted by Marjan Ghotbi
Dr. Katharine Dickson @metaomicsnerd.bsky.social · 31/07/2026
This may be the biggest mistake I’ve ever heard of anyone making in an undergraduate microbiology laboratory - and it wasn’t the students’ fault. arstechnica.com/health/2026/...
arstechnica.com
College lab class ends with 32 people on antibiotics for deadly germ exposure
Lab students were supposed to ID a mild germ. They all identified a deadly pathogen.
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Scripps Institution of Oceanography @scrippsocean.bsky.social · 02/07/2026
🎖️Farooq Azam, a marine microbiologist and Distinguished Professor Emeritus at Scripps Oceanography & @ucsandiego.bsky.social, has earned the prestigious 2026 Kyoto Prize in Basic Sciences! He was recognized for his groundbreaking discoveries on the microbial loop. ⤵️ bit.ly/4y5lcZU
bit.ly
Marine Microbiologist Farooq Azam Receives Kyoto Prize
University of California San Diego marine microbiologist and Distinguished Professor Emeritus Farooq Azam has been selected as the 2026 Kyoto Prize laureate in Basic Sciences. Azam is widely recognize...
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Reposted by Marjan Ghotbi
Martin Polz @polzlab.bsky.social · 06/05/2026
Very excited to share our new paper out in Nature. Congrats to Xiaoqian (Annie) Yu and all the coauthors. www.nature.com/articles/s41...
nature.com
Genome-wide sweeps create ecological units in the human gut microbiome - Nature
Genome-wide selective sweeps commonly occur in the human gut microbiome and can spread across the world within decades to produce epidemic-like population structures.
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Shuai Wang @wshuai.bsky.social · 30/03/2026
Studying DNA modification in microbes shouldn't be limited by methodology. 🧬 We’re excited to introduce MODIFI, our new scalable method for detecting DNA modifications in PacBio metagenomic data and estimating ECE-host linkage. Check out the preprint: www.biorxiv.org/content/10.6...
biorxiv.org
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The Banfield Lab @banfieldlab.bsky.social · 30/03/2026
Congratulations @wshuai.bsky.social and co-authors! We’re excited to introduce MODIFI, our new scalable method for detecting DNA modifications in PacBio metagenomic data and estimating ECE-host linkage. Check out the preprint: www.biorxiv.org/content/10.6...
biorxiv.org
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Tominaga K. (tomiken) @pacyc184.bsky.social · 08/03/2026
Enabling Megascale Microbiome Analysis with DartUniFrac | bioRxiv www.biorxiv.org/content/10.64898/20…
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Reposted by Marjan Ghotbi
Nature Microbiology @natmicrobiol.nature.com · 22/02/2026
#NatMicroPicks Aerobic archaeal-eukaryotic ancestor? 🦠🫁 The ancestor of eukaryotes may have combined hydrogen metabolism with aerobic respiration, shaping early cellular complexity. #MicroSky www.nature.com/articles/s41...
nature.com
Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor - Nature
Sequencing of marine sediments finds 136 newly identified Heimdallarchaeia and several novel lineages, and indicates that Heimdallarchaeia evolved distinct metabolic capabilities from other Asgar...
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Reposted by Marjan Ghotbi
Innovative Genomics Institute @innovativegenomics.bsky.social · 21/01/2026
A new preprint from The Banfield Lab looks at mobile genetic elements with single-cell precision. Read here: ow.ly/hFBX50Y0nQA #microbiology
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Reposted by Marjan Ghotbi
Admirable Women @admirablewomen.bsky.social · 04/02/2026
Remembering Dr. Maryam Mirzakhani on #WorldCancerDay. Dr. Mirzakhani was first woman to win the Fields Medal, the most prestigious award in #mathematics. She died in 2017 from #breastcancer at the age of 40. stanford.io/2C0io2A #WomenInSTEM
A vibrant, composite portrait of the brilliant Iranian mathematician Maryam Mirzakhani (1977–2017), the first woman and first Iranian to win the Fields Medal. She is shown in a close-up head-and-shoulders view, facing the camera with a gentle, thoughtful expression—short brown hair, bright blue eyes, and a calm smile. She wears a navy blue fleece over a teal/green collared shirt. Overlaid transparently behind and around her is a dense blackboard filled with intricate handwritten mathematical equations in white chalk, featuring complex expressions involving binomial coefficients (e.g., n! / (k!(n-k)!)), factorials, summations, powers, and terms suggestive of hypergeometric series or combinatorial identities. The equations partially surround and frame her face, symbolizing her deep immersion in advanced mathematics, particularly in hyperbolic geometry, Teichmüller theory, and dynamical systems, while evoking the creative, exploratory nature of her work as a Stanford professor and groundbreaking researcher.
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BejaLabTechnion @bejalab.bsky.social · 28/01/2026
A prophage-encoded abortive infection protein preserves host and prophage spread www.nature.com/articles/s41...
nature.com
A prophage-encoded abortive infection protein preserves host and prophage spread - Nature
A Gifsy-1 prophage–encoded higher eukaryotes and prokaryotes nucleotide-binding protein, HepS, senses Siphoviridae infection, activates abortive defence by cleaving host transfer RNAs, blocks rival ph...
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Nature Microbiology @natmicrobiol.nature.com · 28/01/2026
go.nature.com
Phosphate availability stabilizes fucoidan produced by marine microalgae
Nature Microbiology, Published online: 22 January 2026; doi:10.1038/s41564-025-02252-9Bacterial degradation of extracellular fucoidan is resource-intensive and, therefore, limited by low-phosphate concentrations. This mechanism provides a competitive advantage to fucoidan-producing microalgae and enhances carbon sequestration.
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Reposted by Marjan Ghotbi
Nature Microbiology @natmicrobiol.nature.com · 23/01/2026
Out Now! Phosphate deprivation restricts bacterial degradation of the marine polysaccharide fucoidan #MicroSky
go.nature.com
Phosphate deprivation restricts bacterial degradation of the marine polysaccharide fucoidan
Nature Microbiology, Published online: 22 January 2026; doi:10.1038/s41564-025-02240-zLimiting phosphate concentrations could be a strategy to protect and sequester carbon dioxide as fucoidan, a polysaccharide produced by marine algae.
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Reposted by Marjan Ghotbi
Cameron Thrash @jcamthrash.bsky.social · 22/01/2026
Our latest. Led by the very talented @ahoiching.bsky.social Cell cycle dysregulation of globally important SAR11 bacteria resulting from environmental perturbation www.nature.com/articles/s41... #jcampubs 🌊
nature.com
Cell cycle dysregulation of globally important SAR11 bacteria resulting from environmental perturbation - Nature Microbiology
Without key cell cycle control genes, SAR11 cells experience aneuploidy and growth inhibition when exposed to changes in nutrients, carbon sources or temperature stress, a vulnerability that may repre...
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Ben Vezina @bananabenana.bsky.social · 22/01/2026
Our new paper on Insertion Sequences (IS) in #Klebsiella - Lineages have vastly different IS loads and profiles - An inverse relationship between IS load and metabolic capacity, in particular phosphorus use, consistent with early reductive evolution. www.microbiologyresearch.org/content/jour...
microbiologyresearch.org
Exploring the IS-capades of Klebsiella pneumoniae: insertion sequences drive metabolic loss in obscure sub-lineages
Introduction. Klebsiella pneumoniae is an opportunistic pathogen that causes a wide spectrum of infections within healthcare settings and the community. Four K. pneumoniae sub-lineages, defined using ...
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Reposted by Marjan Ghotbi
Nature Biotechnology @natbiotech.nature.com · 19/01/2026
TimeVault transforms vault particles into transcriptome recording devices, which are applied to uncover transcriptional heterogeneity in drug-tolerant persister cancer cells #NBThighlight www.science.org/doi/10.1126/...
science.org
A genetically encoded device for transcriptome storage in mammalian cells
Understanding how cells make decisions over time requires the ability to link past molecular states to future phenotypic outcomes. We present TimeVault, a genetically encoded system that records and s...
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Bethany Kolody, PhD @bethanykolody.bsky.social · 14/01/2026
Huge thanks to The Scientist for this feature that really captured the spirit of our research! www.the-scientist.com/how-ocean-cu...
the-scientist.com
How Ocean Currents Shape the Marine Microbiome
Ocean microbes keep the planet healthy by cycling nutrients and capturing carbon, but a detailed and precise map of where they live had never been made—until now.
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Innovative Genomics Institute @innovativegenomics.bsky.social · 15/01/2026
A new preprint on expanding the genetic code, from IGI's Jill Banfield, Peter Penev, and collaborators across the country: ow.ly/HiYO50XVNXR
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The Banfield Lab @banfieldlab.bsky.social · 07/01/2026
New preprint out: Revealing the pervasive landscape of MGE-host interactions in situ with single-cell genomics www.biorxiv.org/content/10.6... @mingyan-igi.bsky.social
biorxiv.org
Revealing the pervasive landscape of MGE-host interactions in situ with single-cell genomics
Mobile genetic elements (MGEs), including plasmids and viruses, drive microbial evolution and ecosystem dynamics, yet their distribution, host range, and functions remain poorly understood, especially...
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Reposted by Marjan Ghotbi
Laura Suttenfield @lcatherines.bsky.social · 05/01/2026
Happy new year! The second big project of my PhD in Rachel Whitaker's lab is now up! 🎉 We look at how provirus infection affects the evolution of the bacterial chromosome with different types of viral induction – with CRISPRs or antibiotics. Take a peek 🦠 www.biorxiv.org/content/10.6...
biorxiv.org
Provirus induction diversifies adaptive variation in Pseudomonas aeruginosa lysogen populations
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that forms chronic infections in people with cystic fibrosis. Often P. aeruginosa strains are lysogens, infected with proviruses, that ...
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Reposted by Marjan Ghotbi
Zamin Iqbal @zaminiqbal.bsky.social · 14/11/2025
Honoured and quite blown-over to receive this award. I have been, and continue to be, very lucky - first with great mentors, and then really prodigious students, postdocs and collaborators. Working with them has been a joy.
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Reposted by Marjan Ghotbi
The Banfield Lab @banfieldlab.bsky.social · 07/10/2025
Newest preprint from the group on megaplasmids in E. coli led by @assemblerag.bsky.social. In addition to our findings in metagenomic datasets, we identified an RNA-seq project from a giant panda gut sample with evidence of megaplasmids. We would like to include the data creators in our study.
doi.org
Megaplasmids associate with Escherichia coli and other Enterobacteriaceae
Humans and animals are ubiquitously colonized by Enterobacteriaceae , a bacterial family that contains both commensals and clinically significant pathogens. Here, we report Enterobacteriaceae megaplas...
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SciLifeLab @scilifelab.se · 08/12/2025
SciLifeLab researchers Maliheh Mehrshad (SLU) and Camilla Engblom (@ki.se) appointed Wallenberg Academy Fellows ↓ 🧪 “This program gives researchers the chance to pursue high-risk, high-gain research ideas” – @mehrshmali.bsky.social Q&A ↓ www.scilifelab.se/news/long-te... @kawresearch.bsky.social
scilifelab.se
Long-term funding to SciLifeLab researchers: “a huge boost and game-changer to starting a lab”
SciLifeLab researchers Maliheh Mehrshad and Camilla Engblom are appointed Wallenberg Academy Fellows, and receive five-year basic research grants.
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Marjan Ghotbi @marjanghotbi.bsky.social · 31/12/2025
Think you need large volumes for microbial experiments? Our recent publication introduces HiMEx, a simple, scalable method for microbial ecology. academic.oup.com/ismecommun/a... 🦠 it provides an easy, efficient approach to capturing viral diversity, opening new opportunities for virome analysis.
academic.oup.com
From microscale to microbial insights: validating high-throughput microvolume extraction (HiMEx) methods for marine microbial ecology
Abstract. Extracting and directly amplifying DNA from small-volume, low-biomass samples would enable rapid, ultra-high-throughput analyses, facilitating th
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Marjan Ghotbi @marjanghotbi.bsky.social · 18/10/2025
Amazing ability of invasive Gracilaria vermiculophylla to control microbial interaction network of its biofilm. academic.oup.com/ismecommun/a...
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