iiinova — where your digital self keeps evolving

Reposted by Maria Dilia Palumbieri

MPI for Biology of Ageing @mpiage.bsky.social · 04/02/2026

Job Alert! The Sprenger Lab is looking for a Postdoc! www.age.mpg.de/job-9f350f6e...

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Reposted by Maria Dilia Palumbieri

Lopes_Lab @lopeslab.bsky.social · 11/09/2025

New important opportunity for young PI recruitment at our Institute! Please spread the news. Interested candidates should carefully check their eligibility for the indicated SNSF funding schemes, before submitting their application 👍 👇 www.imcr.uzh.ch/dam/jcr:3d1f... www.imcr.uzh.ch/en.html

imcr.uzh.ch

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Reposted by Maria Dilia Palumbieri

MPI for Biology of Ageing @mpiage.bsky.social · 24/10/2025

🎉 Celebrating our Amazing Women in Ageing Research! 🎉 Meet Maria, Postdoc in the Matic Lab 👩‍🔬 Maria studies how our cells respond to damage in their DNA — the instruction manual of life. 🧬 @mariapalumbieri.bsky.social

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Maria Dilia Palumbieri @mariapalumbieri.bsky.social · 24/09/2025

Great to see research on ADPrUb, including our work, being highlighted and summarized here:

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Maria Dilia Palumbieri @mariapalumbieri.bsky.social · 24/09/2025

ADPr gets a ubiquitin upgrade: great to see research on ADPrUb, including our work, being highlighted and summarized here: doi.org/10.1038/s415...

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Reposted by Maria Dilia Palumbieri

MPI for Biology of Ageing @mpiage.bsky.social · 24/07/2025

New Video: "Combining Cancer Drugs to Extend Lifespan" 📹 Watch our new video to learn how researchers at the Max Planck Institute for Biology of Ageing discovered that combining Rapamycin and Trametinib significantly extends the lifespan of mice. youtu.be/5L-k4v1TRd0

youtu.be

Live longer - Combination therapy with Rapamycin and Trametinib prolongs the life of mice

YouTube video by Max Planck Institute for Biology of Ageing

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Reposted by Maria Dilia Palumbieri

Nature Chemical Biology @natchembio.nature.com · 10/07/2025

RNF114 is an E3 ligase that can recognize ADP-ribose (ADPr) and ubiquitin with separate domains. A proteomics approach is developed using these domains to map ADP-ribosyl-ubiquitylation sites www.nature.com/articles/s41...

nature.com

Serine ADPr on histones and PARP1 is a cellular target of ester-linked ubiquitylation - Nature Chemical Biology

RNF114 is an E3 ligase that can recognize ADP-ribose (ADPr) and ubiquitin with separate domains. Using these domains, Kolvenbach and Palumbieri et al. developed a proteomics approach to map ADP-ribosy...

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Reposted by Maria Dilia Palumbieri

Andrii Gorelik @andriigorelik.bsky.social · 10/07/2025

An amazing paper from van der Heden and Ahel groups! They use clever chemistry to identify RNF114 as a dual ADP-ribose-Ubiquitin reader involved in the DNA damage response! Congratulations to first authors Max, @chatrin-c.bsky.social and Rishov. Happy to have a small contribution in this story

nature.com

Identification of RNF114 as ADPr-Ub reader through non-hydrolysable ubiquitinated ADP-ribose - Nature Communications

Deltex E3s modify ADP-ribosylated targets with ubiquitin, creating a hybrid modification whose readers remains unknown. Here, the authors synthesise a non-hydrolysable probe that mimics the modificati...

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Maria Dilia Palumbieri @mariapalumbieri.bsky.social · 10/07/2025

Thrilled to share my first first-author postdoc publication — a team effort with @aklvnbch.bsky.social. We present the first MS-based evidence of ADP-ribosylation–linked ubiquitin (ADPrUb) in cells after DNA damage. Grateful for all I’ve learned and looking forward to uncovering more about ADPrUb

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Reposted by Maria Dilia Palumbieri

Andreas Kolvenbach @aklvnbch.bsky.social · 09/07/2025

Really happy that our paper is finally released. We show that PARP1 and histones are targets of ADP-ribosyl-linked ubiquitylation during DNA damage and describe how to detect the dual modification. Great teamwork with @mariapalumbieri.bsky.social & thanks to everyone involved @maticlab.bsky.social !

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Reposted by Maria Dilia Palumbieri

ahellab.bsky.social @ahellab.bsky.social · 24/05/2025

A postdoc position is available in our lab to study ADP-ribosylation and ubiquitylation signalling! We are looking for someone with experience in structural biology and biochemistry. The application deadline is June 20th. my.corehr.com/pls/uoxrecru...

my.corehr.com

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Maria Dilia Palumbieri @mariapalumbieri.bsky.social · 19/05/2025

Thrilled to have presented our latest work at FEBS PARP 2025! A fantastic joint effort with @aklvnbch.bsky.social . I really enjoyed sharing our results and discussing with experts in the field—looking forward to what’s next! Many thanks to the organizers for making this great meeting possible!

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Reposted by Maria Dilia Palumbieri

Lopes_Lab @lopeslab.bsky.social · 07/05/2025

Exciting PhD project available in our lab (time sensitive)! 👇

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Reposted by Maria Dilia Palumbieri

Trends in Biochemical Sciences @cp-trendsbiochem.bsky.social · 25/04/2025

Online now - the Spotlight "Modifying the modifiers: ubiquitination of ADP-ribosylation in human cells" from @kfeijszaja.bsky.social and colleagues. #ADPribosylation #ubiquitination #MARUbylation #crosstalk authors.elsevier.com/sd/article/S...

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Reposted by Maria Dilia Palumbieri

Cologne Graduate School of Ageing Research @cga-age.bsky.social · 20/03/2025

🎥We're excited to share the new film about our graduate programme. Get a glimpse of our faculty & PhD students and explore your research opportunities. Join us as we dive into the world of ageing research and discover what makes the CGA truly unique.👩‍🔬🧑‍🎓 www.ageing-grad-school.de/about-us/cal...

ageing-grad-school.de

Discover the CGA film

Get to know our people & programme

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Reposted by Maria Dilia Palumbieri

The Matić Lab @maticlab.bsky.social · 09/02/2025

We’ve uploaded a bioRxiv preprint on new antibodies specific for poly-ADP-ribosylation (PARylation). These modular tools were developed and validated through novel applications of our Serine ADP-ribosylation-based technology. www.biorxiv.org/content/10.1...

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