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Marcus Low

@marcuslowx.bsky.social
304 followers 553 following 73 posts

Novelist, editor of Spotlight, aspiring epidemiologist, lover of labradors.

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Reposted by Marcus Low
Peter MacPherson @petermacp.bsky.social · 19/09/2026
Very pleased to contribute to this meta-analysis. Among contacts of #TB, protection from preventive therapy waned quickly in high incidence settings, but persisted for years in low and medium incidence settings authors.elsevier.com/sd/article/S... @uofgshw.bsky.social 🦠🧪🛟
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 18/09/2026
KILLER DISEASE | The reasons cryptococcal meningitis continues to take a toll on people living with HIV are varied and complex. Here's some of the key takeaways: tinyurl.com/4bunjacy Join our mailing list: tinyurl.com/82jdsfjy
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Marcus Low @marcuslowx.bsky.social · 14/09/2026
One of the best briefings we’ve published so far
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 09/09/2026
UNPAID AND UNPROTECTED | For years, hospitals have relied on the unpaid, unprotected labour of trainee-specialists to fill their rosters, but these doctors are reaching a breaking point. www.spotlightnsp.co.za/2026/09/09/e...
spotlightnsp.co.za
Exploited and exhausted, SA’s ghost doctors start to rattle their chains
For years, hospitals have relied on the unpaid, unprotected labour of trainee-specialists to fill their rosters, but these doctors are reaching a breaking point. Joan van Dyk reports.
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Marcus Low @marcuslowx.bsky.social · 10/09/2026
Some great reporting here on what is essentially an epidemiology story
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Marcus Low @marcuslowx.bsky.social · 08/09/2026
The value of the OpenSAFELY approach is somewhat underplayed here
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 24/08/2026
World’s largest research funder lifts ban on South Africa The United States National Institutes of Health (NIH) has lifted its ban nearly 18 months after an order to stop work with South...
spotlightnsp.co.za
World’s largest research funder lifts ban on South Africa
The United States National Institutes of Health (NIH) has lifted its ban nearly 18 months after an order to stop work with South Africa. The funding ban created a crisis...
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Marcus Low @marcuslowx.bsky.social · 25/08/2026
Come learn the basics of bNAbs for HIV. Another great briefing article by Catherine Tomlinson.
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Reposted by Marcus Low
Thiru Balasubramaniam @thirugeneva.bsky.social · 19/08/2026
science.org
NIH lifts ban on funding research in South Africa
Researchers who study HIV, tuberculosis, and other infectious disease in the country welcome policy change
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Marcus Low @marcuslowx.bsky.social · 19/08/2026
Very disappointing when a trial turns out to have been underpowered like this.
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 14/08/2026
#InsideTheBox | In his latest column for Spotlight, Dr Andy Gray unpacks the legal background and the current state of the still unfolding regulatory saga surrounding complementary and alternative medicines. www.spotlightnsp.co.za/2026/08/14/i...
spotlightnsp.co.za
Inside The Box with Dr Andy Gray | Are complementary medicines effectively regulated in South Africa?
The regulation of complementary and alternative medicines in South Africa has been hotly contested in recent decades, including in court rooms. In his latest column for Spotlight, Dr Andy Gray unpacks...
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Reposted by Marcus Low
Hacker News Top Stories @hackernewsbot.bsky.social · 11/08/2026
Compression Is Prediction | Discussion
ngrok.com
Compression is prediction | ngrok blog
Compression and LLMs are trying to solve the exact same problem: predicting what comes next. Learn the fundamentals of compression and how better prediction leads to better shrinkage.
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 03/08/2026
OVERLOOKED | Dr Hermann Reuter believes substance abuse is the country’s biggest health issue after HIV, but it's being ignored. Spotlight visited his NGO SAHARA in George to find out how he and his team are helping to change this. www.spotlightnsp.co.za/2026/08/03/d...
spotlightnsp.co.za
Dr Hermann Reuter says the biggest battle after HIV in SA is addiction - and it is being ignored
Dr Hermann Reuter did pioneering work treating HIV in the early 2000s in Cape Town and in the rural Eastern Cape. Today, his focus is substance abuse, which he believes is the country’s biggest health...
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 23/07/2026
Positive interim findings on new once-weekly HIV treatment pill A new antiretroviral combination pill that is taken only once a week appears to work as well as daily pills at treating HIV....
spotlightnsp.co.za
Positive interim findings on new once-weekly HIV treatment pill
A new antiretroviral combination pill that is taken only once a week appears to work as well as daily pills at treating HIV. This is according to interim study findings...
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Marcus Low @marcuslowx.bsky.social · 17/07/2026
A brief history of the Thembisa HIV model, by Leigh Johnson. A great overview of one of the most impressive infectious disease models around papers.ssrn.com/sol3/papers.cfm?abs…
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Reposted by Marcus Low
Hacker News Top Stories @hackernewsbot.bsky.social · 14/07/2026
What will be left for us to work on? | Discussion
normaltech.ai
What will be left for us to work on?
My keynote at ICML 2026
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 13/07/2026
UP CLOSE | Being a researcher who studies tuberculosis in the lab is one thing, having the TB bug in your lungs is quite another. @elri-voigt.bsky.social sat down with two of a relatively small number of people who have experienced both. www.spotlightnsp.co.za/2026/07/13/f...
spotlightnsp.co.za
From test tubes to treatment: Two TB researchers on getting the ancient disease themselves
Being a researcher who studies tuberculosis in the lab is one thing, having the TB bug in your lungs is quite another. Elri Voigt sat down with two of a relatively small number of people who have expe...
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Reposted by Marcus Low
GroundUp News @groundup.org.za · 13/07/2026
The Msunduzi Local Municipality has spent R1.18-billion on a new public transport network that is still not operational. It started planning the project 15 years ago, but it has not moved beyond the first phase of construction. Read groundup.org.za/article/piet... by Joseph Bracken
groundup.org.za
Pietermaritzburg’s R1-billion transport flop
No buses operate on Msunduzi Municipality’s failed public transport system
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 01/07/2026
IN THE SPOTLIGHT | Globally, childhood vaccines have saved an estimated 154 million lives since 1974. In this special briefing, we detail which vaccines are in used in South Africa. www.spotlightnsp.co.za/2026/07/01/i...
spotlightnsp.co.za
In The Spotlight | What is in SA’s vaccination schedule and how does it measure up?
Which vaccines are in use in South Africa and how does our vaccination schedule measure up to international standards? In this #InTheSpotlight special briefing, Catherine Tomlinson unpacks the recent ...
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Marcus Low @marcuslowx.bsky.social · 26/06/2026
SA’s Constitutional Court has found that fair use provisions in the Copyright Amendment Bill are not unconstitutional, as some have argued. It is good to have that settled. The written judgement doesn’t seem to be online yet.
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Reposted by Marcus Low
Francois Venter @francoisventer.bsky.social · 25/06/2026
groundup.org.za/article/impo...
groundup.org.za
Important advance in TB treatment
South African researchers publish trial results in world’s leading medical journal
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 25/06/2026
SHINGLES VACCINE | A new, more effective shingles vaccine is finally set to hit the market in South Africa. The vaccine, Shingrix, should soon be available at private sector pharmacies, but availability in the public sector seems unlikely for the time being. www.spotlightnsp.co.za/2026/06/25/n...
spotlightnsp.co.za
New shingles vaccine to be launched in SA private sector, but affordability may limit access
Ten years after its launch in the United States, a new, more effective shingles vaccine is finally set to hit the market in South Africa. While the vaccine, called Shingrix, should soon be available a...
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Reposted by Marcus Low
Hacker News Top Stories @hackernewsbot.bsky.social · 20/06/2026
Ember, a native iOS Hacker News reader I built around accessibility | Discussion
github.com
GitHub - DatanoiseTV/ember-hackernews: Ember — a native, accessible Hacker News reader for iOS, built in SwiftUI with no third-party dependencies.
Ember — a native, accessible Hacker News reader for iOS, built in SwiftUI with no third-party dependencies. - DatanoiseTV/ember-hackernews
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Marcus Low @marcuslowx.bsky.social · 12/06/2026
This is an excellent and important series from GroundUp. Unfortunately the South African government seems indifferent.
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Marcus Low @marcuslowx.bsky.social · 03/06/2026
Our special briefing ahead of the launch of SA’s lenacapavir rollout
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 02/06/2026
DELAYED AGAIN | Seven months after a Supreme Court of Appeal ruling allowed for specially trained pharmacists to dispense antiretroviral medicines without a doctor’s script, no pharmacists are yet providing these services. Spotlight explores why. www.spotlightnsp.co.za/2026/06/02/w...
spotlightnsp.co.za
Why pharmacists still can’t prescribe ARVs, months after court gave the green light
A Supreme Court of Appeal ruling in October 2025 cleared the way for specially trained and permitted pharmacists to dispense antiretroviral medicines without a doctor’s script. Seven months later, no ...
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Marcus Low @marcuslowx.bsky.social · 15/05/2026
Our take on estimates from Thembisa 5.0
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 15/05/2026
JUST PUBLISHED | The number of people in South Africa on antiretroviral treatment remained roughly unchanged from 2024-2025, according to the newest estimates from the leading mathematical model of HIV in the country. Spotlight unpacks these latest numbers. www.spotlightnsp.co.za/2026/05/15/s...
spotlightnsp.co.za
SA’s ARV programme hardly grew in 2025, according to latest estimates
The number of people in South Africa on antiretroviral treatment remained roughly unchanged from 2024 to 2025, according to just-published estimates from the leading mathematical model of HIV in the c...
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Reposted by Marcus Low
Clinical Infectious Diseases @cidjournal.bsky.social · 02/05/2026
The latest CID supplement issue examines key aspects of tuberculosis (TB), including transmission, disease progression, diagnostic approaches, and treatment strategies. ↪️ bit.ly/3On4jaL
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 11/05/2026
LENACAPAVIR IN KZN | Spotlight visited northern KwaZulu-Natal to see first-hand how collaborative efforts will bring a groundbreaking HIV prevention jab to an area where HIV infection rates remain stubbornly high. www.spotlightnsp.co.za/2026/05/11/a...
spotlightnsp.co.za
Along dusty roads in KZN, a push for a groundbreaking HIV prevention jab takes shape
Along dusty roads in northern KwaZulu-Natal, Biénne Huisman speaks to youth leaders, community mentors and leading scientists who are collaborating to bring a groundbreaking HIV prevention jab to this...
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Reposted by Marcus Low
GroundUp News @groundup.org.za · 04/05/2026
Makhudu Sefara stepped aside as editor of the Sunday Times and chair of the SANEF last week. This followed the Special Investigating Unit (SIU) naming him in an investigation into the alleged misuse of Lottery funds. Read groundup.org.za/article/sane... by GroundUp Editors
groundup.org.za
SANEF should do better than this
Its defensive response to recent criticism does not earn the public’s confidence in news media
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 24/04/2026
THE STAKES ARE HIGH | The Constitutional Court will soon hear the first two of several major court challenges relating to the National Health Insurance Act. Read our newsletter for the crucial takeaways: tinyurl.com/bddwsha9 Join our mailing list: tinyurl.com/82jdsfjy
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Reposted by Marcus Low
James Packard Love @jamielove.bsky.social · 29/04/2026
19 years ago, these 10 NGOs issued a statement opposing a WIPO broadcasting treaty. Not much has changed. web.archive.org/web/20070707...
web.archive.org
Knowledge Ecology International
Home of Knowledge Ecology International
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Reposted by Marcus Low
Kristof Decoster @kristofdecoster.bsky.social · 22/04/2026
Vaccines mean malaria deaths should be falling — not rising www.nature.com/articles/d41... Nature Editorial.
nature.com
Vaccines mean malaria deaths should be falling — not rising
The tools exist to end this killer disease. It is the money and the will that are lacking.
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Marcus Low @marcuslowx.bsky.social · 18/04/2026
After a few weeks of playing with Claude Code, writing Rust code from scratch feels like waking up from an extended fever dream. Suddenly things are clear and concrete again.
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Marcus Low @marcuslowx.bsky.social · 15/04/2026
We covered the US research funding cuts and their impact on SA in some detail last year. I’m glad we could circle back to it.
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Reposted by Marcus Low
Clinical Infectious Diseases @cidjournal.bsky.social · 05/04/2026
When are uncontrolled trials in TB scientifically and ethically justified: Borrowing wisdom from early AIDS clinical trials ✅ Just Accepted 🔗 bit.ly/4bPWGTk
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 10/04/2026
MOOD MUSIC | The health department needs a world-class manager. President Cyril Ramaphosa’s decision for a new Director-General will say a lot about how serious he is about fixing our many health challenges, argues Spotlight editor @marcuslowx.bsky.social. www.spotlightnsp.co.za/2026/04/10/r...
spotlightnsp.co.za
Ramaphosa’s choice of Director-General for Health will test his commitment to building a capable state
When push comes to shove, President Cyril Ramaphosa’s talk of building a more capable state hasn’t always been backed up by the appointment of committed and capable people to key government positions. His decision regarding a new Director-General for health will say a lot about how serious he actually is about addressing the country’s many health challenges, argues Spotlight editor Marcus Low.
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 08/04/2026
OUR BIG READ | Despite the urgent need for new tools to tackle obesity and weight-related illness in people with HIV, there has been very little research to date on GLP-1 use in people with HIV. www.spotlightnsp.co.za/2026/04/08/w...
spotlightnsp.co.za
What breakthrough weight loss meds might mean for people with HIV
In part 3 of a Spotlight special series on the role of new weight loss medicines like Ozempic in South Africa, we ask what these breakthrough jabs might mean for people living with HIV in the country....
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 07/04/2026
Some healthcare workers in the public sector are allowed to moonlight in the private sector under certain conditions. But amid broader management dysfunction, many are bending these rules to avoid backlash. www.spotlightnsp.co.za/2026/04/07/m...
spotlightnsp.co.za
Moonlighting, money and morals in a looted health system
The Department of Health allows some public sector doctors and nurses to moonlight in the private sector, but the relevant policy and its implementation caused much controversy over the years. Set aga...
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Reposted by Marcus Low
GroundUp News @groundup.org.za · 07/04/2026
CCTV footage shows police officers repeatedly assaulting a Mowbray barber, Juma Igiranieza. Yet, two years later – some of the officers involved – have not only escaped justice, they remain on active duty. Read groundup.org.za/article/how-... by GroundUp Editors
groundup.org.za
How criminal cops escape justice
Delmore Manuel, Jermaine Conradie, and Leigh-Ann Maroon are getting away with torture
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Reposted by Marcus Low
Clinical Infectious Diseases @cidjournal.bsky.social · 29/03/2026
Diagnostic Yield of Tongue Swab- Compared to Sputum-Based Molecular Testing for Tuberculosis in Four High-Burden Countries ✅ Just Accepted 🔗 bit.ly/4dNKt2M
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Clinical Infectious Diseases @cidjournal.bsky.social · 31/03/2026
Are We Ready for the Gift Tongues Can Give to TB? ✅ Just Accepted 🔗 bit.ly/4dfHkIU
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Marcus Low @marcuslowx.bsky.social · 01/04/2026
Much of what we know about asymptomatic TB in one accessible briefing.
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Spotlight @spotlightnsp.bsky.social · 31/03/2026
#InsideTheBox | The sale of illegal medicines is a significant threat to public safety. Does the South African Health Products Regulatory Authority have the necessary tools to provide protection in this area, asks Dr Andy Gray in his latest column. www.spotlightnsp.co.za/2026/03/31/i...
spotlightnsp.co.za
Inside The Box with Dr Andy Gray | Are there appropriate sanctions for non-compliance with medicines legislation in South Africa?
The sale of illegal medicines is a significant threat to public safety. In his latest Inside The Box column, Dr Andy Gray asks whether the South African Health Products Regulatory Authority has the ne...
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 01/04/2026
FLU | As the flu season kicks off slightly earlier than usual, Spotlight asks experts what we might expect from this year's season and what we know about a new flu strain that's making the rounds. www.spotlightnsp.co.za/2026/04/01/f... @elri-voigt.bsky.social @tuliodna.bsky.social
spotlightnsp.co.za
Flu season is here, with experts keeping a close eye on new flu strain
Many regions in the Northern Hemisphere experienced a slightly earlier start to their flu season, driven in some part by a novel variant of influenza A(H3N2). As our flu season also kicks off slightly...
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 25/03/2026
DEPRESSION IN SA | Around 3.8 million people in South Africa developed depression in 2024, estimate leading local researchers in a major new modelling study. www.spotlightnsp.co.za/2026/03/25/w...
spotlightnsp.co.za
Well over three million people in SA develop depression every year, researchers estimate
Around 3.8 million people in South Africa developed depression in 2024, estimate leading local researchers in a major new modelling study.
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Reposted by Marcus Low
Spotlight @spotlightnsp.bsky.social · 19/03/2026
ELIMINATING TB | New TB tests have massive potential for South Africa’s struggle to get to grips with the disease. Utilising them will require both ambition and smart implementation, argue Dr Gaurang Tanna and Dr Yogan Pillay. www.spotlightnsp.co.za/2026/03/19/t... @gatesfoundation.bsky.social
spotlightnsp.co.za
To eliminate TB, we need to make testing more accessible and affordable
New TB tests have massive potential for South Africa’s struggle to get to grips with the age-old disease. Making the most of these new tests will require both ambition and smart implementation, argue ...
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Marcus Low @marcuslowx.bsky.social · 23/03/2026
A fascinating long read for World TB Day #tbsky @stoptb.bsky.social @madhupai.bsky.social @treatmentactiongroup.org @tomscriba.bsky.social
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