iiinova — where your digital self keeps evolving

Reposted by Marco Stock

Antonio Scialdone @antonio-scialdone.bsky.social · 23/12/2025

Great work led by @marcostock.bsky.social and Florin Ratajczak , thanks to all coauthors Paul Bertin @evahoermanseder.bsky.social @yoshuabengio.bsky.social Jason Hartford @interactome.bsky.social Matthias Heinig @alextong.bsky.social

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Reposted by Marco Stock

Eva Hörmanseder @evahoermanseder.bsky.social · 22/12/2025

The credit goes to my colleagues @meghana-oak.bsky.social and @marcostock.bsky.social, who drove this project and continued these demanding experiments with incredible persistence

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Reposted by Marco Stock

Antonio Scialdone @antonio-scialdone.bsky.social · 12/02/2025

Great team effort, led by @marcostock.bsky.social , with Corinna Losert, @mattezambon.bsky.social, Niclas Popp, Gabriele Lubatti, @evahoermanseder.bsky.social & Matthias Heinig

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Reposted by Marco Stock

Meghana Oak @meghana-oak.bsky.social · 22/01/2025

✨ Excited to share my latest preprint on how H3K4 methylation promotes transcriptional memory from gametes to embryos across a transcriptionally silent window — crucial for proper zygotic genome activation and development. 🐸🧬✨ 📄 Check it out here: doi.org/10.1101/2025... 👇 Highlights below

doi.org

H3K4 methylation-promoted transcriptional memory ensures faithful zygotic genome activation and embryonic development

In the life of a vertebrate embryo, gene expression is initiated for the first time at zygotic genome activation (ZGA). Maternally expressed transcription factors present in the embryo are essential f...

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Nikolai Slavov @slavov-n.bsky.social · 23/12/2024

UMAP applied to 100 randomly generated points from a multivariate normal distribution simplystatistics.org/posts/2024-1...

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Saez-Rodriguez Group @saezlab.bsky.social · 23/12/2024

We present Gene Regulatory nETwork Analsyis (GRETA), a framework to infer, compare and evaluate gene regulatory networks #GRNs. With it, we have benchmarked multimodal and unimodal GRN inference methods. Check the results here 👇 Paper: doi.org/10.1101/2024.12.20.629764 Code: github.com/saezlab/greta

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Sushmita Roy @sroyyors.bsky.social · 01/12/2024

Learning on graphs 2024 recordings are all available online: youtube.com/watch?v=Af-_... logconference.org what a great resource!

youtube.com

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Mitch Guttman @mitchguttman.bsky.social · 27/11/2024

Gene regulation involves thousands of proteins that bind DNA, yet comprehensively mapping these is challenging. Our paper in Nature Genetics describes ChIP-DIP, a method for genome-wide mapping of hundreds of DNA-protein interactions in a single experiment. www.nature.com/articles/s41...

nature.com

ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements - Nature Genetics

ChIP-DIP (ChIP done in parallel) is a highly multiplex assay for protein–DNA binding, scalable to hundreds of proteins including modified histones, chromatin regulators and transcription factors, offe...

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