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"The things that make us human will become much more important instead of much less important."

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Ludwig Oxford is delighted to welcome Dr Manav Pathania as an Assistant Member of the Ludwig Institute for Cancer Research, Oxford Branch.

The FlyBase team’s fundraising efforts have proven successful in the short term, but restoration of its federal grant remains uncertain.

A high-speed pipeline enables whole-mouse imaging and mesoscopic analysis of peripheral nerves using transgenic, immunostaining, and viral labeling, providing an effective means to map body-wide struc...

Spatial transcriptomics reveals distinct microglial mechanisms driving amyloid-β clearance in both passively and actively immunized patients with Alzheimer’s disease.

Mice models often fail to reflect human telomere biology. Here, the authors engineer a mouse strain with a humanized mTert gene, restoring telomere length regulation to a human-like pattern. This mode...

Glioblastoma is a highly aggressive primary brain tumor with glioblastoma stem cells (GSCs) enforcing the intra-tumoral hierarchy. Plasma cells (PCs) …

Transposable element exonization can yield functional protein isoforms as seen for primate-specific IFNAR2.

Inflammatory monocytes are identified as important players in T cell restimulation in the tumour microenvironment.

The prodrug gliocidin effectively kills glioblastoma cells by targeting de novo purine synthesis, improving survival in mouse models.

Models of pediatric high-grade glioma reveal genotype–phenotype associations, differences in cell type composition, and sensitivity to targeted and combination therapy approaches, making preclinical e...

Abstract. Central nervous system neuroblastoma with FOXR2 activation (NB-FOXR2) is a high-grade tumor of the brain hemispheres and a newly identified molecular entity. Tumors express dual neuronal and...