Sign in

Michał Małszycki

@malszycki.bsky.social
152 followers 287 following 9 posts

Postdoc in the Laboratory of RNA Biology at IIMCB in Warsaw 🧬🔬 Passionate about Evolution and RNA Biology.

PostsRepliesMedia
Michał Małszycki @malszycki.bsky.social · 20/07/2026
😁
020
Reposted by Michał Małszycki
iimcb.bsky.social @iimcb.bsky.social · 15/07/2026
🚀 Dr. Michał Małszycki @malszycki.bsky.social, postdoctoral researcher in the RNA Biology Laboratory at IIMCB, has been awarded an EMBO Postdoctoral Fellowship @embo.org #EMBOFellowship #PostdoctoralFellowship #RNABiology #MolecularBiology #LifeSciences #IIMCB
031
Reposted by Michał Małszycki
iimcb.bsky.social @iimcb.bsky.social · 07/07/2026
🧬 At the Genome Engineering Facility, the IN-MOL-CELL infrastructure supports researchers in developing genetically modified and transgenic mouse models using CRISPR/Cas9 technology. 👉 Learn more: inmolcell.iimcb.gov.pl #IIMCB #INMOLCELL #GenomeEngineering #CRISPRCas9 #RareDiseaseResearch
311
Michał Małszycki @malszycki.bsky.social · 25/02/2026
I’m thrilled to share that my PhD work has been just published in Cell. After a long and bumpy ride, we uncovered the core function of nuclear speckles -splicing of GC-levelled exons- and traced the evolution of this gene architecture and condensates themselves to amniotes.
Graphical abstract: Speckle-proximal and speckle-dependent RNA has short introns, and simultaneous emergence of multiple exons requires heightened concentration of spliceosome components.
Speckle-independent RNA has long introns and can be spliced well with or without speckles
Speckle dependent introns evolved in amniotes. The reduction in intron length was accompanied by the increase of the intronic GC content, giving rise to GC-levelled intronic architecture. This exon-intron architecture is not present outside of amniotes (Fish, Invertebrates), and these organisms lack nuclear speckles.
08322
Reposted by Michał Małszycki
Nature @nature.com · 21/04/2025
Nature research paper: Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines go.nature.com/4cAPx85
go.nature.com
Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines - Nature
Upon intramuscular administration, COVID-19 mRNA vaccines are primarily taken up by macrophages, in which the cellular machinery extends their poly(A) tails, thereby increasing mRNA stability and translation, providing an explanation for the efficacy of these vaccines.
0216
Reposted by Michał Małszycki
Michal Gdula @michal-gdula.bsky.social · 05/02/2026
We’re recruiting! Three-year, fully funded #postdoc opportunity: pancreatic cancer #epigenetics & potential new treatments (funded by @ncn.gov.pl & @dfg.de ). Collaboration with @akispapantonis.bsky.social, University of Göttingen (OPUS-LAP). See the ad & contact me! drive.google.com/file/d/1vrFd...
0105
Reposted by Michał Małszycki
Institute of Molecular Biotechnology @imbavienna.bsky.social · 25/02/2026
We are hiring! Join the Jachowicz lab as a postdoctoral researcher. The project focuses on understanding the dynamics of ncRNAs using high-resolution and single-molecule microscopy approaches. Link below 👇
196
Reposted by Michał Małszycki
Forum Akademickie @forumakademickie.bsky.social · 23/02/2026
Państwo, które rezygnuje z nagradzania jakości i odwagi konkurowania w nauce, samo ogranicza swoje aspiracje i ustępuje miejsca przy światowym stole. System powinien wzmacniać, a nie wyrównywać w dół – pisze dziś w FA prof. Magdalena Musiał-Karg z Uniwersytetu im. Adama Mickiewicza w Poznaniu ⬇️
forumakademickie.pl
Między ambicją a wygodą
Debata o przyszłym kształcie listy czasopism w Polsce coraz częściej przybiera ton tożsamościowy. Padają określenia „globaliści”, „lokaliści”, „scopusowcy”, pojawiają się sugestie o klasowym charakter...
012
Michał Małszycki @malszycki.bsky.social · 23/02/2026
Academics should really consider moving off X. Staying there is giving the platform credibility, so it can algorithmically disseminate propaganda. I logged into X from polish IP recently and was appalled by the level of pro-russian and anti-EU propaganda directly in my feed.
041
Reposted by Michał Małszycki
Nature @nature.com · 21/01/2026
Researchers have engineered magnetically controlled fluorescent proteins that can be remotely dimmed and brightened in cells and living animals go.nature.com/3NUSY12
go.nature.com
‘Remote controlled’ proteins illuminate living cells
The discovery that some fluorescent proteins are sensitive to magnets could lead to the development of switchable drugs and biosensors.
45522
Reposted by Michał Małszycki
Nature @nature.com · 14/01/2026
Many US scientists have reported a rise in targeted harassment. Here are tools and tips to safeguard your cybersecurity go.nature.com/4jFQnnt
go.nature.com
Six steps to protect researchers’ digital security
Many US scientists have reported a rise in targeted harassment. Here are tools and tips to safeguard your cybersecurity.
05226
Reposted by Michał Małszycki
David Bartel's Lab @bartellab.bsky.social · 06/01/2026
We are thrilled to share our latest work uncovering the mechanistic basis of target-directed microRNA degradation (TDMD). This work was driven by @jakobfarnung.bsky.social and @elenaslo.bsky.social in a fantastic collaboration with Brenda Schulman's lab. tinyurl.com/E3TDMD (1/5)
29630
Michał Małszycki @malszycki.bsky.social · 12/12/2025
The link from the image: meetings.embo.org/event/26-rna...
meetings.embo.org
RNA localization and local translation
Gene expression is regulated through a series of complex, coordinated events, including the localization of specific RNA molecules to distinct subcellular locations. This subcellular organization of …
010
Reposted by Michał Małszycki
Matthew Taliaferro @jmtali.bsky.social · 08/12/2025
Announcing the 2026 edition of the EMBO workshop on RNA localization and local translation! This meeting will be held June 30 - July 4 near Porto, Portugal. Come for exciting updates in the field from both established investigators and trainees. See the link below for details!
13719
Reposted by Michał Małszycki
The Night Science Podcast @nightsciencepod.bsky.social · 08/12/2025
🔥 New episode of the Night Science Podcast! Maria Leptin is the President of the ERC, the European Research Council. She discusses how funding agencies can better support bold ideas and we explore how to evaluate creativity in grant proposals. @marialep.bsky.social open.spotify.com/episode/2AJj...
0185
Reposted by Michał Małszycki
Science Magazine @science.org · 08/12/2025
The December issue of #ScienceImmunology is out! This month's cover highlights the juvenile axolotl's ability to regenerate its thymus after complete removal—possibly making it an exception among vertebrates. Learn about this research and more: scim.ag/4anWlqv
This month’s cover features the Mexican axolotl Ambystoma mexicanum, which has the ability to regenerate its thymus de novo, an apparent exception among vertebrates.
17613
Reposted by Michał Małszycki
Max Planck Institute for Molecular Genetics @molgen.mpg.de · 04/12/2025
🧬 Are you fascinated by alternative splicing? Join Florian Heyd’s lab @freieuniversitaet.bsky.social & #IMPRS-BAC #gradschool for your PhD! Strong background in molecular biology and cell culture needed. 👉 www.molgen.mpg.de/5120514/Heyd...
052
Michał Małszycki @malszycki.bsky.social · 26/11/2025
Cuuute!
000