Our latest paper is finally out! We are showing the significance of the podoplanin/CLEC-2 signaling axis beyond controlling cellular mechanics and actomyosin contractility.
#fibroblasts #podoplanin #stroma #inflammation
@actonlab.bsky.social
www.cell.com/cell-reports...
cell.com
Lymph node fibroblast phenotypes and immune crosstalk regulated by podoplanin activity
Makris et al. show that podoplanin regulates the transcription profile of lymph node
fibroblasts. Podoplanin deletion drives inflammation, disrupts lymph node architecture,
and attenuates stromal/immu...
