iiinova — where your digital self keeps evolving

Lee Zamparo @lzamparo.bsky.social · 02/10/2026

What about West of St. George? No trains headed Eastbound it seems

Lee Zamparo @lzamparo.bsky.social · 23/09/2026

Spending more and more time lately on data synthesis. My current mood: it's both way more interesting than I initially thought, but also way more vexing than I initially thought.

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Lee Zamparo @lzamparo.bsky.social · 31/08/2026

Anything else that didn't make the Abandon slide?

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Lee Zamparo @lzamparo.bsky.social · 27/08/2026

clearly I haven't been paying close attention , as this isn't even their first physical robot released

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Lee Zamparo @lzamparo.bsky.social · 27/08/2026

Okay, I appreciate that HuggingFace wants to put a happier face on robotics, but it's a bit off brand, no? www.axios.com/2026/08/27/hugging-fa…

axios.com

www.axios.com

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Lee Zamparo @lzamparo.bsky.social · 14/08/2026

I think your last sentence sums it up. The remedy for bad policy should be better representative government that will make better policy, not a legal decision.

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Lee Zamparo @lzamparo.bsky.social · 14/08/2026

I'm surprised that this is the test that needs to be applied. But here we are.

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Lee Zamparo @lzamparo.bsky.social · 14/08/2026

[59] says that the question was whether there was a rational connection between reducing congestion and increased lanes. Judge clarified in [59] the gov't *didn't need to establish rationality* (??) but that the plantiffs did have to establish irrationality.

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Lee Zamparo @lzamparo.bsky.social · 14/08/2026

For the third time, I accept that. I accept that the court decided this was a legislative issue, not a charter issue to be decided by a court.

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Lee Zamparo @lzamparo.bsky.social · 14/08/2026

That's the legal decision, which I have no issue with. But I have an issue with a judge saying his common sense disagrees with expert testimony in a different domain, therefore the experts are probably wrong. I don't think judge vibes should supersede expertise.

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Lee Zamparo @lzamparo.bsky.social · 14/08/2026

Story says Stel..is intends to sell the plant: "the company has indicated its intent to open discussions with another company about the potential sale of the plant." Most trad automakers already have plants here. Might be BYD / Geely looking to buy so it can sell++ into the Canadian market

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Lee Zamparo @lzamparo.bsky.social · 14/08/2026

The decision may be correct, but some of the reasoning is appalling: the passages citing the "common sense" of more road lanes mean less traffic, and that "yeah they had an expert engineer but induced demand is just a theory, over which my own common sense prevails". cf bsky.app/profile/matt...

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Lee Zamparo @lzamparo.bsky.social · 14/08/2026

The province is legally able to pursue terrible policy, even if it suspects that it's bad policy, as long as it also expresses a public hope that it is not.

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Lee Zamparo @lzamparo.bsky.social · 13/08/2026

Ditto. I'm really bullish on the prospect of research centric discussion coming here rather than Twitter or (sigh) LinkedIn

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Reposted by Lee Zamparo

Eugene Vinitsky 🍒 @eugenevinitsky.bsky.social · 12/08/2026

For the past six months @mariaa.bsky.social and I have been working on creating an improved research experience on atproto. It's now live! Check out: lea.ac

leaflet.pub

Lea: research-oriented social media

Introducing a beta-version of our new research-focused social media platform

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Lee Zamparo @lzamparo.bsky.social · 12/08/2026

It's harder to hit upon a more relevant question than "what should Toronto become", yet I think we all acknowledge that the official plan is never going to be an animating issue.

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Reposted by Lee Zamparo

old roadside pics @roadside.xor.blue · 11/08/2026

the ferm, kenoza lake, new york, 1976

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Lee Zamparo @lzamparo.bsky.social · 11/08/2026

Cybercrime-based publicity as a service?

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Lee Zamparo @lzamparo.bsky.social · 11/08/2026

Amalgamation is the spectre that hangs over us always

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Lee Zamparo @lzamparo.bsky.social · 11/08/2026

"Hydro corridors for kilometers in every direction" eh? I must have missed the hydro corridor running east west through the city so people can get to where they want to go. Also the corridor(s) running north south to where people work, study, shop. Do people genuinely believe this nonsense?

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Lee Zamparo @lzamparo.bsky.social · 11/08/2026

Ever thus in ON. Part of this effect seems like habitual underestimation by ON gov to get it done. Part (I suspect) is regulation in ON pushing costs up, but I'd be glad to be wrong here. Part (I fear) are so few companies / consortia bid to build these complex infra that the public gets hosed

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Lee Zamparo @lzamparo.bsky.social · 11/08/2026

As far as I know they've evolved into peptide weirdos, but I limit expose for health reasons so ymmv

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Lee Zamparo @lzamparo.bsky.social · 11/08/2026

I believe the removal promise, but not the "build something else" promise. Pass.

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Lee Zamparo @lzamparo.bsky.social · 10/08/2026

Looks like a huge joint effort that will have a "rising tide" effect on so many research questions. Bravo to everyone involved!

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Reposted by Lee Zamparo

Quaid Morris @quaidmorris.bsky.social · 07/08/2026

Excited to share the results of the Codebook Project, an international effort to identify accurate DNA-binding motifs and genomic binding loci for >300 uncharacterized human transcription factors (TFs) www.nature.com/articles/s41...

nature.com

An expanded codebook of human transcription factor DNA-binding specificity - Nature

Results from a panel of assays that analyse different aspects of DNA sequence specificity reveal more than 100 new motifs to aid the characterization of putative human transcription factors.

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Lee Zamparo @lzamparo.bsky.social · 10/08/2026

Yes, this is what I was referring to, glad I didn't confabulate it. ... Oh no!

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Lee Zamparo @lzamparo.bsky.social · 10/08/2026

Wasn't there a Black Mirror episode about just this form of dystopian future?

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Lee Zamparo @lzamparo.bsky.social · 08/08/2026

They probably are still looking for parking

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Lee Zamparo @lzamparo.bsky.social · 06/08/2026

Amazed it took an MLS team this long to "buy low" on Lozano, esp as a loan

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Lee Zamparo @lzamparo.bsky.social · 05/08/2026

Worm ppl have had this for years, and when I first found out about that it blew my mind. This is more astounding still

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Lee Zamparo @lzamparo.bsky.social · 05/08/2026

Nobody wants to involve the "if everyone else jumped off a bridge" hypothetical in public, but not examining important aspects of measurement make work worse.

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Lee Zamparo @lzamparo.bsky.social · 03/08/2026

whatever the designation, I think we'd all be happier if people just used a modicum of sense and realized it was Wrong

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Lee Zamparo @lzamparo.bsky.social · 02/08/2026

I think Duolingo Max gives you this, but man that's a lot of cashiola

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Reposted by Lee Zamparo

Henry Yuen @henryyuen.bsky.social · 01/08/2026

Some initial thoughts, and a complicated mix of feelings. Wow. I mean, Erdos problems are cool (I genuinely mean that), I didn't know about the Jacobian conjecture before it got disproved. But this newest batch from OpenAI hits home in a way the previous announcements did not.

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Reposted by Lee Zamparo

Jay Shendure @jshendure.bsky.social · 30/07/2026

New preprint from Shendure Lab on Locus-Scale aka Long-@$$ MPRAs led by the amazing Abby McGee & @carinabiar.bsky.social Most MPRAs test ~300 bp fragments next to a promoter. But real enhancers are bigger, act combinatorially and from a distance. 1/n www.biorxiv.org/content/10.6...

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Lee Zamparo @lzamparo.bsky.social · 30/07/2026

recall watching it in theatre as a 10yo. That part where they're scaling the electrified fence while the other group is trying to restore the power 😬

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Lee Zamparo @lzamparo.bsky.social · 30/07/2026

(that was painful to type out)

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Lee Zamparo @lzamparo.bsky.social · 29/07/2026

Are parameters learned, or are they also trained?

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Lee Zamparo @lzamparo.bsky.social · 28/07/2026

In a province that seems very committed to keeping things they way they are, it's bizarre that we cannot apply this principle to Billy Bishop

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