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Lisa Pavinato

@lisapavinato.bsky.social
88 followers 221 following 16 posts

Postdoctoral researcher working at IOR - Bellinzona 🇨🇭 Passionate for neurodevelopment and neurogenetics, studying genetic human diseases. 🧬 #Stem cells and brain #organoids enthusiast 👀🧫

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Lisa Pavinato @lisapavinato.bsky.social · 27/05/2025
🥼 Do you want to start working with human pluripotent stem cells? 📖 Check out our protocols collection "Good practices in hPSC handling", developed among the CorEuStem COST Action Project at COST Association #stemcells www.protocols.io/view/good-pr...
protocols.io
Good practices in hPSC handling
This protocol collection provides a comprehensive and practical guide for the maintenance, passaging, freezing, and thawing of human pluripotent stem cells (hPSCs). Designed to...
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Lisa Pavinato @lisapavinato.bsky.social · 19/05/2025
Happy to share our latest work on #CAPRIN1 linked #NDD at #neurogen25! Thanks to @dmmjournal.bsky.social for supporting my attendance at this exciting conference ✨ #DMMgrants
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Reposted by Lisa Pavinato
Emily R. Trunnell, Ph.D. @ertrunnell.bsky.social · 31/03/2025
🆕 in human 🧠 research! The @bhadurilab.bsky.social at @uclastemcell.bsky.social generated a metabolomic atlas of human cortical development using both primary tissue and stem-cell derived #organoids. The work identified a new regulator of radial glia cell fate. 🧪 www.biorxiv.org/content/10.1...
biorxiv.org
Metabolic Atlas of Early Human Cortex Identifies Regulators of Cell Fate Transitions
Characterization of cell type emergence during human cortical development, which enables unique human cognition, has focused primarily on anatomical and transcriptional characterizations. Metabolic pr...
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Lisa Pavinato @lisapavinato.bsky.social · 17/03/2025
🌟Finally out! 🧬One year ago we linked RPH3A gene to a #neurodevelopmental disorder. Now, Barzasi and team showed some variants we previously described are causing dysfunction of pre- and post- glutamatergic synapse! Have a look www.nature.com/articles/s41...
nature.com
Arg209Lys and Gln508His missense variants in Rabphilin 3A cause pre- and post-synaptic dysfunctions at excitatory glutamatergic synapses - Scientific Reports
Scientific Reports - Arg209Lys and Gln508His missense variants in Rabphilin 3A cause pre- and post-synaptic dysfunctions at excitatory glutamatergic synapses
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Lisa Pavinato @lisapavinato.bsky.social · 17/02/2025
Proud to be part of the Autism Sequencing Consortium, which keeps on contributing to the understanding of the genetics of neurodevelopmental disorders! Have a look at our recent work 👇
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Lisa Pavinato @lisapavinato.bsky.social · 10/02/2025
We need to stop this never-ending history of not accessible papers. Science needs to be shared, and we should find a solution. How can a paper from *1993* still not being accessible?!! #OpenScience
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Lisa Pavinato @lisapavinato.bsky.social · 28/01/2025
❓How does a cell become malignant? 🌟Several tightly regulated factors are needed to lead the cell toward a state of ‘oncogenic competence’. 🔖In this Opinion, we highlight the most updated findings about the mechanisms behind *oncogenic competence*. ➡️https://authors.elsevier.com/c/1kW698Z12ybWbi
An image extrapolated from a scientific paper, graphically showing the role of differentiation state and microenvironment in oncogenic competence
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Lisa Pavinato @lisapavinato.bsky.social · 07/01/2025
2025 starts with two novel works in the field of neurodevelopmental disorders-linked genes! ▶️ RICTOR, a novel genes involved in NDDs pubmed.ncbi.nlm.nih.gov/39738822/ ▶️ TAOKs, a family of protein causing NDDs pubmed.ncbi.nlm.nih.gov/39737487/ Thanks to all the collaborators 💪
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Reposted by Lisa Pavinato
Cedric Boeckx @cedricboeckx.bsky.social · 10/12/2024
Very happy @ellylewerissa.bsky.social & @naelnadifkasri-lab.bsky.social are presenting our collective effort (co-led by O. Leonardi from G. Testa’s lab) to capture the role of CHD2 dosage in neurodevelopment (for disease & evolution), using organoids + 2D neurons #cshl2024brain (Poster 111, today!)
[Cortical Organoid image acquired by Oliviero Leonardi]
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Lisa Pavinato @lisapavinato.bsky.social · 09/12/2024
Starting the week with 7+ hours of cell culture be like: 🫠🫠
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Lisa Pavinato @lisapavinato.bsky.social · 03/12/2024
When I was a child I loved reading, and I wanted to become a writer ✍ Who knew I was destined to write for work...not books of course, but scientific stuff! However, my name is finally also in a book, as we have been invited to write a (continue 👇)
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Lisa Pavinato @lisapavinato.bsky.social · 28/11/2024
Our last report is out today! 💥 Who works in the field of neurodevelopmental disorders knows how difficult may be to understand genomic data results, especially when the clinical presentation is different than the expected one. continue 👇
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