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Laboratory of Genomic Stability

@lgs-imb.bsky.social
375 followers 732 following 5 posts

Institute of Molecular Biology, BAS #DNArepair #Replication #Genomeintegrity #Cancer #Anticancerdrugs #Microscopy

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Laboratory of Genomic Stability @lgs-imb.bsky.social · 30/04/2026
We are excited to share our latest research now published in Cell Reports. Together with Hyun Lee and Masato Kanemaki lab, we investigate the mechanism underlying the exclusion of FUS and EWSR1—and show that this process is driven by RNA pol II. #dnarepair #fus #dnadamage #DDR #transcription
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Reposted by Laboratory of Genomic Stability
Nature Cell Biology @natcellbio.nature.com · 16/04/2025
👋Our April issue's out! Cover: Live #chromosome tracking 👉🏼Perspective on #lactylation 👉🏼Review on #MechanicalForces in development 🔬 #MyocardialInfarction #PreclinicalStudy #NeuralStemCells #proteostasis #neurodegeneration #mitochondria #CellDeath #cancer & more! www.nature.com/ncb/volumes/...
Chromosomes in rainbow colors inside blue nuclei on a black background
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Reposted by Laboratory of Genomic Stability
Fena Ochs @fenaochs.bsky.social · 13/11/2024
Hi Bluesky! I made a 3D chromatin starter pack. Let me know if you would like to be added. go.bsky.app/6tTQdqQ
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Reposted by Laboratory of Genomic Stability
Anders Sejr Hansen @andersshansen.bsky.social · 16/01/2025
Excited to share James Jusuf's preprint: By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%) We quantify mESC 36k loops: <loops> are generally rare (2.3%) www.biorxiv.org/content/10.1...
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Laboratory of Genomic Stability @lgs-imb.bsky.social · 07/04/2025
We’re excited to share our work where we investigated the mechanisms of chromosome motion by tracking all #chromosomes, mapping their interactions, and live cell karyotyping, using #AI based denoising, segmentation and registration, published in Nature Cell Biology. www.nature.com/articles/s41...
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