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Lucas Toshio Ito

@lcstoshio.bsky.social
49 followers 122 following 0 posts

PhD student at @unifesp | Psychiatric Genetics | Bioinformatics | Neuroimaging | Data Viz

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Reposted by Lucas Toshio Ito
Biological Psychiatry @biologicalpsych.bsky.social · 08/08/2026
Genetic risk scores for depression predict a more severe and worsening trajectory of depressive symptoms from childhood into young adulthood.
biologicalpsychiatryjournal.com
Polygenic Risk for Major Depression: Diagnostic Specificity and Developmental Trajectories in an Admixed Youth Cohort
Major Depressive Disorder (MDD) is heritable and polygenic, yet the relative diagnostic specificity, developmental impact, and cross-ancestry generalizability of MDD polygenic risk scores (MDD-PRS)…
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Reposted by Lucas Toshio Ito
Sarah Colbert @sarahcolbert.bsky.social · 27/10/2025
🚨New preprint from PGC SUI!! @pgcgenetics.bsky.social GWAS meta-analyses of suicidal ideation, attempt, death, and behavior across >50 cohorts identify 77 loci (59 novel), implicate subcortical brain regions, and show suicidality phenotypes are genetically distinct. www.medrxiv.org/content/10.1...
medrxiv.org
Genome-wide association studies identify 77 loci for suicidality and provide novel biological insights
Suicidality is heritable and a leading cause of global morbidity and mortality, yet its biological etiology remains largely elusive. We conducted multi-ancestry genome-wide association study meta-anal...
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Reposted by Lucas Toshio Ito
Anna Docherty @annadocherty.bsky.social · 19/10/2025
The PGC Suicide Working Group will provide a symposium at #WCPG2025 🇲🇽 covering our latest multi-ancestry GWAS and CNV meta-analyses, sex-specific meta-analyses, and GxEHR analyses. 🥳 @lcstoshio.bsky.social @andreyshabalin.bsky.social @sarahcolbert.bsky.social @caina89.bsky.social
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Reposted by Lucas Toshio Ito
Elizabeth F Mattera @lizmattera.bsky.social · 24/04/2025
@sarahcolbert.bsky.social ‘s #SRS25 presentation: Genome-Wide Association Studies of Suicidal Thoughts and Behaviors in the Psychiatric Genomics Consortium So incredible!
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Reposted by Lucas Toshio Ito
Elizabeth Atkinson @egatkinson.bsky.social · 02/04/2025
📃 I am excited to share our @naturegenet.bsky.social review paper on the state of psychiatric genetics in Latin America, put forth by the Latin American Genomics Consortium (LAGC)! 🎉 www.nature.com/articles/s41...
nature.com
Psychiatric genetics in the diverse landscape of Latin American populations - Nature Genetics
Latin America and the Caribbean remain largely underrepresented in psychiatric genetics research. This Review highlights the need for more research in these populations to advance genetic insights and...
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