Reposted by Lucas Toshio Ito
Genetic risk scores for depression predict a more severe and worsening trajectory of depressive symptoms from childhood into young adulthood.
biologicalpsychiatryjournal.com
Polygenic Risk for Major Depression: Diagnostic Specificity and Developmental Trajectories in an Admixed Youth Cohort
Major Depressive Disorder (MDD) is heritable and polygenic, yet the relative diagnostic specificity, developmental impact, and cross-ancestry generalizability of MDD polygenic risk scores (MDD-PRS)…