Read the latest News & Comment articles from Nature Reviews Immunology

Onkar et al. discuss the current landscape of therapeutic cancer vaccines in the context of recent clinical trials, with a special focus on neoantigen vaccines. They also highlight challenges and scop...

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Background Bispecific T cell-engagers (BTEs) are engineered antibodies that redirect T cells to target antigen-expressing tumors. BTEs targeting tumor-specific antigens such as interleukin 13 receptor...

A preprint by Xu et al. shows that MHC-pseudotyped retroviruses can reprogramme, activate and expand tumour-specific T cell populations in vivo.