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Lasse Middendorf

@lassemiddendorf.bsky.social
200 followers 403 following 7 posts

PhD Student at @CRG.eu | Synthetic Biology, Proteins & Evolution 🧬 | AI4ProteinDesign Lab

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Lasse Middendorf @lassemiddendorf.bsky.social · 04/02/2026
AI is everywhere in biology right now, but how do these models actually hold up once they hit the lab? Our latest review on generative AI for enzyme design cuts through the hype to see what’s actually working in the lab🧪 ⬇️LINK
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Mohammed AlQuraishi @moalquraishi.bsky.social · 10/02/2025
It's long seemed that molecular biology is a natural home for ML interpretability research, given the maturity of human-constructed models of biological mechanisms—permitting direct comparison with their ML-derived counterparts—unlike vision and NLP. Our first foray below👇.
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Claudia Alvarez Carreño @claudiaalcar.bsky.social · 29/01/2025
Join the ProSE Seminar Series! A monthly discussion on the #Evolution of #ProteinStructure 🧪 Next up: Andrei Lupas “Highly repetitive genomic ORFs: a source of new fibrous proteins?” 11th February | 3 PM GMT 🔗 Register here: tinyurl.com/prose-seminar1
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Paul Gardner @ppgardne.bsky.social · 25/01/2025
This is an important problem. 👏
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Lasse Middendorf @lassemiddendorf.bsky.social · 29/11/2024
Highlighting the amazing research at the #CRGPhDSymp2024 Poster Session! Check out some snapshots from today’s sessions
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nuriamimbrero.bsky.social @nuriamimbrero.bsky.social · 29/11/2024
Super interesting talk from Gül Aydin’s about understanding the role of dynamic DNA methylation at promoters during B-cell differentiation at the #CRGPhDSymp2024
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iseultleahy.bsky.social @iseultleahy.bsky.social · 29/11/2024
Kicking us off today is Tamara Perteghella from the Guigó lab with her talk on the latest release of #GENCODE, dramatically increasing the number of annotated lncRNAs. Well done to everyone involved in the consortium! #CRGPhDSymp2024
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Al Jord Lab @aljordlab.bsky.social · 29/11/2024
PhD Symposium at @theprbb.bsky.social ! #PhD #symposium #prbb
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Lasse Middendorf @lassemiddendorf.bsky.social · 29/11/2024
People are slowly getting settled for the second day of the #CRGPhDSymp2024
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nuriamimbrero.bsky.social @nuriamimbrero.bsky.social · 28/11/2024
Learning about cell type diversity and evolution beyond gene expression thanks to the amazing talk from Paulina Spurk at the PhD Symposium. #CRGPhDSymp2024
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Matteo Zambon @mattezambon.bsky.social · 28/11/2024
Great talk from Laia Montes Espuna at the @crg.eu PhD Symposium! Her work is focused on cell type diversity in early metazoans, aiming at broadening the understanding of cell type identity programs across the animal kingdom 🪸🧬 #CRGPhDSymp2024
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iseultleahy.bsky.social @iseultleahy.bsky.social · 28/11/2024
Navigating the #CRGPhDSymp2024 poster session, I’m slowly becoming an expert at nodding thoughtfully while frantically trying to understand someone’s life work in 3 minutes!
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iseultleahy.bsky.social @iseultleahy.bsky.social · 28/11/2024
Great talk from Javier Navarro Delgado on understanding, predicting and engineering variant effects in synthetic antibodies. #AntibodyDiscover #CRGPhDSymp2024
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nuriamimbrero.bsky.social @nuriamimbrero.bsky.social · 28/11/2024
Very interesting talk from Pablo Lanuza about mechanistic understanding of splicing, titled SPF45 and 3'splice site proofreading. #CRGPhDSymp2024 #splicing
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iseultleahy.bsky.social @iseultleahy.bsky.social · 28/11/2024
Thanks Charlie for opening the PhD Symposium! Many thanks to everyone involved in its organisation. #CRGPhDSymp2024
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Lasse Middendorf @lassemiddendorf.bsky.social · 28/11/2024
Next up we have @javibiotec.bsky.social talking on using large-scale mutational experiments to understand the genetic architecture of nanobody stability #CRGPhDSymp2024
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Lasse Middendorf @lassemiddendorf.bsky.social · 28/11/2024
Reporting from the #CRGPhDSymp2024 today and tomorrow! Kicking it off with a fascinating talk Gioia Quarantani on DMS of a 1000 exons to investigate alternative splicing
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Centre de Regulació Genòmica (CRG) @crg.eu · 28/11/2024
Our amazing CRG PhD community are celebrating their annual symposium today and tomorrow. Follow our first year students on Bluesky for snippets about all the amazing talks featured this year: @lassemiddendorf.bsky.social @mattezambon.bsky.social @iseultleahy.bsky.social
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Noelia Ferruz @noeliaferruz.bsky.social · 27/11/2024
Ah, we have several positions open!
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