Sign in

The Milinkovitch-Tzika lab

@lanevol.bsky.social
348 followers 202 following 50 posts

Our biologists, physicists, computer scientists & mathematicians investigate the evolution & development of Life’s complexity 🐊 🐍 🦎 @genevunige.bsky.social

PostsRepliesMedia
The Milinkovitch-Tzika lab @lanevol.bsky.social · 29/09/2026
Gonzo has always been wonderfully hard to define. Popular Science asked what biology might make of him, and I suggested looking closely at his tuft. Is it hair or feathers? Each answer tells a different evolutionary story. Sometimes the joy of science begins with a playful question.
popsci.com
What kind of animal is Gonzo? What kind of animal is Gonzo? The Muppets won't say, so we asked biologists.
Gonzo’s most distinct feature is also his most baffling: his beak. (Or is it a nose?)
000
The Milinkovitch-Tzika lab @lanevol.bsky.social · 01/09/2026
🐘 ➡️ 🤖 From elephant biomechanics to soft robotics. With Lucia Beccai’s Soft BioRobotics Perception Lab at IIT, our new paper presents ELEANOR: anlarge soft robotic arm inspired by the elephant trunk—continuous, compliant, and highly deformable. 🔗 doi.org/10.1002/aisy... #SoftRobotics
doi.org
Continuous and Large‐Scale: ELEANOR, the Soft Architected Arm Inspired by the Elephant Trunk
A large-scale, architected continuum robot inspired by the macroscopic properties of the African elephant trunk achieves adaptive elephant-like movements and whole-body grasping. The results demonstr...
041
The Milinkovitch-Tzika lab @lanevol.bsky.social · 18/08/2026
🚨 New from LANE 🦎🐍 Pierre-Yves Helleboid & Athanasia Tzika uncover how reptile pigment cells diversify: distinct progenitor trajectories can converge on similar mature states, with previously undescribed chromatophore subtypes in bearded dragons. www.nature.com/articles/s41...
nature.com
Conserved and lineage-specific mechanisms drive chromatophore differentiation in reptiles - Nature Communications
Gene expression analysis of pigment cells in snake and lizard embryos and comparison with fish and frog shows that progenitors follow different developmental paths in each species yet mature cells pre...
1103
The Milinkovitch-Tzika lab @lanevol.bsky.social · 06/08/2026
A pleasure attending the workshop “Collective Movement and Pattern Formation: Biology, Modelling and Analysis” at @icms-edinburgh.bsky.social. A fascinating exchange on collective cell migration, pattern formation, mathematical modelling and analytical methods across biology and medicine.
020
Reposted by The Milinkovitch-Tzika lab
Biology-UNIGE @biology-unige.bsky.social · 07/07/2026
Congratulations @lanevol.bsky.social for your latest publication in @pnas.org showing how hair patterns are organized before birth @genevunige.bsky.social @sciencesunige.bsky.social Press release: unige.ch/medias/en/20... Full text: pnas.org/doi/10.1073/...
032
The Milinkovitch-Tzika lab @lanevol.bsky.social · 03/07/2026
How mammals get their fur? New research from the Milinkovitch-Tzika lab, published in PNAS, shows that chemotaxis—cells moving toward chemical cues—drives hair follicle precursor self-organization during embryonic development, generating diverse fur patterns across mammals. doi.org/10.1073/pnas...
doi.org
Chemotactic self-organization captures the dynamics of mammalian hair follicle patterning | PNAS
The spatial patterning of mammalian hair follicle precursors in embryonic skin is most commonly studied in the laboratory mouse (Mus musculus), whe...
03111
The Milinkovitch-Tzika lab @lanevol.bsky.social · 18/06/2026
Just published in @pnasnexus.org : our collaboration with Soft BioRobotics Perception Lab (IIT, Genova) reveals how Asian elephant trunk skin combines protection, grasping and tactile sensing—a blueprint for soft robotic skins. doi.org/10.1093/pnas...
doi.org
Functional anisotropy of the elephant trunk skin: A biological blueprint for grasping, protection, and tactile sensing
Abstract. Muscular hydrostats, like the elephant trunk, face a fundamental biomechanical conflict between robust protection and delicate manipulation. How
0136
Reposted by The Milinkovitch-Tzika lab
Sergi Roig Puiggros @sroig.bsky.social · 02/06/2026
Thrilled to shared our new preprint with @djabaudon.bsky.social ! Led by Ilaria Morassut, we explored "the extent to which early brain maturation requires interactions with the outside world". This wouldn't have been possible without our incredible collaborators, specially the @lanevol.bsky.social 🧵
32415
The Milinkovitch-Tzika lab @lanevol.bsky.social · 08/05/2026
Charles Darwin comes back to life to wish Sir David Attenborough a happy 100th birthday. Our 3.5-min film from the LANE (University of Geneva) celebrates "the man who helped the world fall in love with nature". Happy #AttenboroughDay ! #bbc @biology-unige.bsky.social
youtu.be
An extraordinary guest to celebrate Sir David Attenborough
YouTube video by The LANE channel
0105
The Milinkovitch-Tzika lab @lanevol.bsky.social · 04/05/2026
Elephants in the spotlight! Two recent features highlight research from the Milinkovitch lab: @quantamagazine.bsky.social on the mechanics behind African elephant skin cracking, and Horizon on how elephant trunk biomechanics inspire versatile soft robotic grippers. www.lanevol.org/news/article...
0105
The Milinkovitch-Tzika lab @lanevol.bsky.social · 15/04/2026
Modelling the dexterity of the elephant trunk! 🐘 By reducing high-dimensional biological movements into simplified linear relationships, we provide new insights into natural muscle coordination for soft robotics. New in @cp-iscience.bsky.social ! 📄 doi.org/10.1016/j.is...
020
The Milinkovitch-Tzika lab @lanevol.bsky.social · 24/03/2026
Grateful to Nancy Steinacker, Barb Matt, and Bruce Bradley for a wonderful visit to the Linda Hall Library . It was a delight to see so many remarkable works—including first editions of Newton’s Principia and Darwin’s On the Origin of Species.
011
The Milinkovitch-Tzika lab @lanevol.bsky.social · 23/03/2026
Really glad to see that my talk at the #StowersSeminarSeries resonated so well. Many thanks to Tatjana and everyone at Lab Piotrowski, as well as the PIs, staff, and students who took the time to share their work inspiring. The Stowers Institute is an incredible environment for doing great science.
051
The Milinkovitch-Tzika lab @lanevol.bsky.social · 12/03/2026
Fascinating discussions yesterday at the 2026 Spring Meeting of the German Physical Society @dpgphysik.bsky.social in Dresden. Thanks to Kristian Franze for the invitation to speak about tissue mechanics. Our 3D prints of crocodile embryos sparked a lot of curiosity among researchers and students.
161
The Milinkovitch-Tzika lab @lanevol.bsky.social · 22/01/2026
Turn scientific data into tangible objects! Some of our 3D models can be downloaded or ordered as 3D prints at low cost (resin + delivery only). Ideal for teaching, research discussions, or showcasing developmental biology. www.lanevol.org/visual-media... #3DPrinting #ScienceEducation #OpenScience
03512
The Milinkovitch-Tzika lab @lanevol.bsky.social · 19/01/2026
Discover how our research comes to life in 3D! Explore digital 3D models from surface scanning and volumetric imaging directly on our website. Each model includes scientific context, videos, and VR/AR exploration. 🔗 www.lanevol.org/3d-models #3DModels #ScienceVisualization #OpenScience
0144
The Milinkovitch-Tzika lab @lanevol.bsky.social · 12/01/2026
Our research on reptile pigmentation is featured on the cover of Genetics 🧬🦎 We uncover how mutations in TYR, SLC24A5, and OCA2 shape hypomelanism in snakes & geckos, revealing modular and flexible melanogenesis. 🔗 academic.oup.com/genetics/art...
0115
The Milinkovitch-Tzika lab @lanevol.bsky.social · 04/12/2025
Our research on snake skin color patterning is featured in The Scientist! 🐍🎨 Athanasia Tzika explains how comparative genomics and CRISPR-Cas9 revealed the key role of specific genes in establishing corn snake skin color patterns. 🔗 www.the-scientist.com/how-do-snake...
the-scientist.com
How Do Snakes Get Their Colorful Stripes and Blotches?
Comparing the genomes of snakes with distinct coloration patterns pinpointed the genetic variants that contribute to these intricate designs.
073
The Milinkovitch-Tzika lab @lanevol.bsky.social · 20/11/2025
Rewatching Prehistoric Planet with my kids and loving how artists #MPCVFX show dinosaurs with scale-by-scale skin colors, similar to some lizards and snakes. Check how our research uncovers the mechanisms behind this phenomenon:
160
The Milinkovitch-Tzika lab @lanevol.bsky.social · 12/11/2025
Many thanks to the PhD students and postdocs at D-BSSE in Basel for hosting me in their seminar series — and to the PIs at the Biozentrum, University of Basel, for inspiring conversations. @bsse.ethz.ch @biozentrum.unibas.ch
182
The Milinkovitch-Tzika lab @lanevol.bsky.social · 03/11/2025
Wonderful visit to @embl.org Heidelberg! Grateful to Alexandre Aulehla and @aikmi.bsky.social for the invitation and to all the group leaders, post-docs and students for the stimulating discussions. Amazing science and a great community! #EMBL #ScienceTalk #DevelopmentalBiology
090
The Milinkovitch-Tzika lab @lanevol.bsky.social · 08/09/2025
🐊 New 90‑second video: watch the digital model of a #crocodile head side‑by‑side with a stunning multi‑material #3Dprint. ▶️ Video: youtu.be/3roeSI-HBbg?... 📖 Nature Article: rdcu.be/d3dnd 🎬 Full explainer (26K+ views, multiple languages): youtube.com/playlist?lis...
youtu.be
From 3D Modelling to 3D Printing - The Movie
YouTube video by The LANE channel
041
Reposted by The Milinkovitch-Tzika lab
V4SDB @v4sdb.bsky.social · 06/09/2025
#V4SDBMeeting2025 is family friendly & makes science attractive & accessible to our youngest participants from @sumbalovakoledova.bsky.social lab. Many thanks to Michel C. Milinkovitch @lanevol.bsky.social for the illustrative 3D printed models of 🐊 snout patterning!
031
Reposted by The Milinkovitch-Tzika lab
V4SDB @v4sdb.bsky.social · 06/09/2025
Our invited speaker for this session is Michel C. Milinkovitch @lanevol.bsky.social from the University of Geneva @biology-unige.bsky.social, who will be presenting his lab’s multidisciplinary research into Patterning: How Reptiles Got Their Looks! #V4SDB2025 #developmentalbiology #evodevo
062
The Milinkovitch-Tzika lab @lanevol.bsky.social · 08/09/2025
Had a great time at @v4sdb.bsky.social 2025 in Slovakia with James Sharpe & Anne Grapin-Botton. Fantastic talks and flawless organization—huge thanks to our wonderful hosts Zuzana Sumbalová Koledová, Dušan Fabián, Marcela Buchtová & Alexandra Špirková! v4sdb2025.img.cas.cz
290
The Milinkovitch-Tzika lab @lanevol.bsky.social · 11/07/2025
🐊 Our multilingual video on the mechanics behind crocodile head scale patterning has now reached 25,000+ views! Discover how skin folds—not genes—shape these stunning patterns. 🎥 Watch here: www.youtube.com/playlist?lis... #CrocodileScales #Science #NaturePaper #Mechanobiology
youtube.com
The mechanics of crocodile head scales patterning - YouTube
010
The Milinkovitch-Tzika lab @lanevol.bsky.social · 23/06/2025
🐢 The tortoise head is sculpted by physics and genes! Our new research shows that tortoise head scales form through two distinct processes: 👉 Chemical signaling shapes the sides 👉 Mechanical stress folds the top 🔗 cell.com/iscience/ful... @cellpress.bsky.social @biology-unige.bsky.social
cell.com
Chemical and mechanical patterning of tortoise skin scales occur in different regions of the head
Biological sciences; Zoology; Evolutionary biology
0166
Reposted by The Milinkovitch-Tzika lab
Springer Nature @springernature.com · 28/03/2025
The distinctive pattern of scales on the face and jaws of crocodiles is formed by a precise mechanical process of skin folding, according to a OA study in @nature.com: spklr.io/63328fZXu #Science #Evolution #Crocodiles
043
Reposted by The Milinkovitch-Tzika lab
Biology-UNIGE @biology-unige.bsky.social · 12/06/2025
📻Interview du Prof. Milinkovitch @lanevol.bsky.social pour la #RTS : Les écailles de tortue se forment de deux façons www.rts.ch/audio-podcas... @genevunige.bsky.social
rts.ch
Les écailles de tortue se forment de deux façons
Chez les vertébrés, la formation des plumes, des poils et des écailles est généralement dictée par des facteurs génétiques moléculaires. Les écailles situées sur la tête des crocodiles font exception,...
031
Reposted by The Milinkovitch-Tzika lab
Rory Cooper @rorylcooper.bsky.social · 04/06/2025
Excited to share our new research in @cp-iscience.bsky.social! We reveal that tortoise head scales are sculpted through two distinct developmental processes - chemical signalling and mechanical folding 🐢🔬🧪 @lanevol.bsky.social @genevunige.bsky.social www.cell.com/iscience/ful...
cell.com
Chemical and mechanical patterning of tortoise skin scales occur in different regions of the head
Biological sciences; Zoology; Evolutionary biology
24923
The Milinkovitch-Tzika lab @lanevol.bsky.social · 28/05/2025
Hanging out with Stanislav Smirnov in 'Les Diablerets' (Switzerland). Great speakers at the workshop organised by Karsten Kruse and Jean-Pierre Eckmann. indico.global/event/9640/r... Will we come up with a math theory of biology?
000
The Milinkovitch-Tzika lab @lanevol.bsky.social · 14/05/2025
Can Turing and Ising models explain lizard skin color patterns—and be reconciled? 🦎📐 We bridge microscopic cell interactions & macroscopic scale patterns across evolutionary divergent lizards. 👉 www.lanevol.org/news/article... #EvoDevo #TuringPatterns #IsingModel #MathematicalBiology
072
The Milinkovitch-Tzika lab @lanevol.bsky.social · 22/04/2025
🚨 We make the cover of Open Biology! Boosting sonic hedgehog signalling in chicken embryos flips the script of skin patterning—chemical pre-patterns give way to mechanical folding. 🧬 From Turing to tissue mechanics. 🧪 ➡️ royalsocietypublishing.org/doi/10.1098/... #shh #DevBio @royalsociety.org
royalsocietypublishing.org
Exacerbated sonic hedgehog signalling promotes a transition from chemical pre-patterning of chicken reticulate scales to mechanical skin folding | Open Biology
Many examples of self-organized embryonic patterning can be attributed to chemically mediated systems comprising interacting morphogens. However, mechanical patterning also contributes to the emergenc...
073
Reposted by The Milinkovitch-Tzika lab
PLOS Biology @plosbiology.org · 14/04/2025
The March 2025 issue of @plosbiology.org is live, and the cover is finger-lickin' good! Many thanks to @rorylcooper.bsky.social & @lanevol.bsky.social for this stunning cover image of a developing chick embryo wing. journals.plos.org/plosbiology/...
The wing of a chick embryo at the twelfth day of incubation, with feather buds covering the entire embryonic wing.
0274
The Milinkovitch-Tzika lab @lanevol.bsky.social · 14/04/2025
Thrilled to share that our light-sheet #microscopy image has been selected as @plosbiology.org's Featured Image for March 2025! This visualization captures the role of the sonic #hedgehog pathway in #feather morphogenesis. 🧬 Dive into the details: www.lanevol.org/news/article...
031
The Milinkovitch-Tzika lab @lanevol.bsky.social · 10/04/2025
🐍 New in Genome Biology! We show #CLCN2 is key to #colorpatterns in corn #snakes. LTR-retrotransposon mutation drives Stripe phenotype. Genomic & transcriptomic analyses reveal insights into trait diversification! Full study: genomebiology.biomedcentral.com/articles/10....
genomebiology.biomedcentral.com
Regulatory and disruptive variants in the CLCN2 gene are associated with modified skin color pattern phenotypes in the corn snake - Genome Biology
Background Snakes exhibit a broad variety of adaptive colors and color patterns, generated by the spatial arrangement of chromatophores, but little is known of the mechanisms responsible for these spe...
1167
Reposted by The Milinkovitch-Tzika lab
Genetics & Evolution (UNIGE) @genevunige.bsky.social · 24/03/2025
🦖➡️🕊️ La RTS met en lumière la dernière publication de @lanevol.bsky.social sur l’évolution des plumes! Découvrez comment cette étude révèle les secrets fascinants de leur formation. 🧐✨ À lire ici 👉 rts.ch/info/science... #science #évolution #plumes #dinosaures
rts.ch
Du dinosaure à l'oiseau, les secrets de l'évolution des plumes révélés dans une étude genevoise
Les plumes, essentielles à la thermorégulation, au vol et à la communication chez les oiseaux, trouvent leur origine dans des appendices plus simples, les protoplumes, présents chez certains dinosaure...
011
Reposted by The Milinkovitch-Tzika lab
PLOS Biology @plosbiology.org · 21/03/2025
The Shh pathway is a key regulator of feather development. @rorylcooper.bsky.social & @lanevol.bsky.social show that inhibiting Shh during chick embryogenesis results in unbranched #feather buds, similar to those seen in some of their #dinosaur ancestors 🧪 @plosbiology.org plos.io/4bIYQCx
Sonidegib treatment arrests feather bud outgrowth and invagination. Light sheet fluorescent microscopy of nuclear stained (TO-PRO-3) chicken wings at E14 reveals the morphological effect of sonidegib treatment. Left: Control samples exhibit normal development of elongated feather buds with well-advanced follicles and visible barb ridges (white arrow). Middle: A dose-dependent effect of sonidegib treatment, with higher doses resulting in shorter feather buds and less advanced follicle development. Right: Samples treated with 300 µg sonidegib exhibit minimal feather bud outgrowth, the fusion of feather buds (white oval dotted outline), absent branching morphogenesis, and no follicle invagination (blue arrow).
0183
The Milinkovitch-Tzika lab @lanevol.bsky.social · 21/03/2025
🦖➡️🕊️ From dinosaur simple proto-feathers to bird intricate feathers? Our latest study shows that feather development is highly resilient to perturbations. 🧐✨ Read more here 👉 www.lanevol.org/news/article... #evolution #feathers #dinosaurs #birds
lanevol.org
News
021
Reposted by The Milinkovitch-Tzika lab
Genetics & Evolution (UNIGE) @genevunige.bsky.social · 18/03/2025
🎙️🦖🌑 Il y a 150 millions d’années, le pelage des mammifères était sombre! Une équipe sino-belge l’a découvert, et Michel Milinkovitch (@lanevol.bsky.social) en décrypte les implications dans CQFD (RTS). Ne manquez pas son analyse! 🔎✨ Ecoutez ici: avisdexperts.ch/fr/intervent... #évolution #science
avisdexperts.ch
L'évolution du pelage des mammifères | Avis d’expert-e-s
011
Reposted by The Milinkovitch-Tzika lab
Genetics & Evolution (UNIGE) @genevunige.bsky.social · 13/03/2025
🔬 Conférence | Oncologie de précision : la révolution de l’IA Avec Pr. Olivier Michielin, médecin-chef, Département d’oncologie aux HUG. 📍 INGE, Rue Jean-F. Bartholoni 6, Genève — 1er étage, Les Salons 📅 Lu 24 mars, 18H30 ℹ️ Plus d'infos : inge.ch/evenements/o...
001
The Milinkovitch-Tzika lab @lanevol.bsky.social · 25/02/2025
🧐🔬 Les écailles des crocodiles ne sont pas programmées génétiquement, mais émergent sous l'effet de contraintes mécaniques ! Découvrez comment notre étude éclaire ce phénomène fascinant dans @pourlascience.bsky.social 👉 www.pourlascience.fr/sd/biophysiq...
pourlascience.fr
La formation des écailles des crocodiles est guidée par des facteurs mécaniques
Une étude révèle que l’apparition des motifs sur la tête des crocodiles ne résulte pas de la génétique, mais d’un processus purement mécanique de compression de l’épiderme.
021
Reposted by The Milinkovitch-Tzika lab
Rory Cooper @rorylcooper.bsky.social · 07/02/2025
Check out this baby crocodile emerging from its egg 🥚 🐊 And read our recent article in @nature.com to learn how compressive forces sculpt their intricate head scales 🧪 www.nature.com/articles/s41... @lanevol.bsky.social @genevunige.bsky.social
07917
The Milinkovitch-Tzika lab @lanevol.bsky.social · 05/02/2025
🔬 Discover The LANE YouTube Channel! 🌍 Our amazing videos help you understand complex biological processes through groundbreaking research at the UNIGE. 🧬✨ Subscribe and join the journey! 📺🔔👇 📌 www.youtube.com/@thelanechan... #Evolution #Science #Research #Biology #Innovation #LifeScience
youtube.com
The LANE channel
Welcome to the channel of the 'LANE' (Laboratory of Artificial & Natural Evolution): the Lab of Michel Milinkovitch at the University of Geneva, Switzerland. Our multidisciplinary team of biologists,...
011
The Milinkovitch-Tzika lab @lanevol.bsky.social · 23/01/2025
A must read! www.science.org/doi/10.1126/... A tunable metamaterial microwave absorber inspired by #chameleon’s color-changing mechanism (described in our work: www.nature.com/articles/nco...) @genevunige.bsky.social
science.org
A tunable metamaterial microwave absorber inspired by chameleon’s color-changing mechanism
Crisscross structures inspired by chameleon’s color changing mechanism achieve tunable electromagnetic response in microwaves.
000
The Milinkovitch-Tzika lab @lanevol.bsky.social · 13/01/2025
🐊 A stunning short movie summarizes our research on how the #crocodile got its head #scales. The following playlist gives you access to versions in English, Chinese, Japanese, German, French and Spanish. @nature.com
youtube.com
The mechanics of crocodile head scales patterning - YouTube
041
The Milinkovitch-Tzika lab @lanevol.bsky.social · 09/01/2025
How the Crocodile Got Its Scales 🐊 —we make the cover of @nature.com ! Our research reveals that the crocodile head scale pattern isn’t genetically-controlled. It’s mechanically self-organized through compressive folding of the skin. 📖 www.lanevol.org/news/article...
0258
The Milinkovitch-Tzika lab @lanevol.bsky.social · 08/01/2025
🎉 We're excited to share our new research in @nature.com ! We reveal that crocodile head scales self-organize through compressive folding of the skin - a mechanical twist on their development & evolution! Please read & share 🐊🔬 @genevunige.bsky.social
nature.com
Self-organized patterning of crocodile head scales by compressive folding - Nature
Crocodile head scales self-organize through purely mechanical compressive skin folding rather than a patterning process controlled by gene interactions.
17131
The Milinkovitch-Tzika lab @lanevol.bsky.social · 08/01/2025
Watch our video to learn how compressive forces sculpt the intricate head scales of #crocodiles! 🎥🐊 And read the full @nature.com article here ⬇️ nature.com/articles/s41... @rorylcooper.bsky.social @genevunige.bsky.social
youtu.be
The mechanics of crocodile head scales patterning
YouTube video by The LANE channel
13310
The Milinkovitch-Tzika lab @lanevol.bsky.social · 08/01/2025
Front cover alert 🚨 Our research on the mechanics behind a dog's iconic wet nose is featured on the @currentbiology.bsky.social cover! Learn how skin growth & blood vessels shape those unique grooves & domes - a must read for #biology & #physics fans 🐶🔬 www.cell.com/current-biol...
020