iiinova — where your digital self keeps evolving

In our latest issue: A human iPSC-based perfusable and membrane-free neurovascular unit-on-chip connecting brain organoids to the blood–brain barrier. #OpenAccess from Elly M. Hol, Helga E. de Vries et al @ellyhol.bsky.social @utrechtuniversity.bsky.social Read now: pubs.rsc.org/LC/article/d...

Visual abstract. The CONNECT chip links a perfusable human blood–brain barrier to brain organoids without a porous membrane, enabling direct neurovascular interactions and simultaneous assessment of barrier function and brain responses.

022

Lab on a Chip @labonachip.rsc.org · 06/10/2026

On the back cover of issue 19 of Lab on a Chip: Enhancing LIBS detection of oil-borne metallic microparticles via acoustic manipulation chip-based enrichment. Xiaolong Lu, Wenjuan Liu et al. pubs.rsc.org/LC/article/d...

back cover of issue 19 of Lab on a Chip: Metallic nanoparticles on microchannel being examined via laser

000

Lab on a Chip @labonachip.rsc.org · 05/10/2026

On the inside front cover of issue 19 of Lab on a Chip: Chemically bonded microfluidic device with integrated laser-induced graphene electrodes. #OpenAccess from Lema Amiry, Rose K. Phull & Darius G. Rackus @torontometsci.bsky.social @torontomet.bsky.social Read now: pubs.rsc.org/LC/article/d...

inside front cover of issue 19 of Lab on a Chip: Glass microfluidic chip with chemical structures surrounding it

020

Lab on a Chip @labonachip.rsc.org · 02/10/2026

On the front cover of issue 19 of Lab on a Chip: Translation, sorting and enrichment: acoustic valve micro robotic system for multifunctional micro manipulation. Xianming Qin et al. pubs.rsc.org/LC/article/d...

front cover of issue 19 of Lab on a Chip: Blood cells travelling across miniature motorway

000

Lab on a Chip @labonachip.rsc.org · 21/09/2026

On the inside front cover of issue 18 of Lab on a Chip: Integration of multi-stacked biodegradable PLGA membranes into microfluidic organ-on-a-chip devices for tunable barrier co-culture. Jungkyu Jay Kim et al pubs.rsc.org/LC/article/d...

inside front cover of issue 18 of Lab on a Chip: Rendering of stacked membranes for co-culture on microfluidic chip

021

Lab on a Chip @labonachip.rsc.org · 17/09/2026

On the front cover of issue 18 of Lab on a Chip: Spatially programmable deterministic lateral displacement for multi-stage microfluidic separation. Takasi Nisisako et al. pubs.rsc.org/LC/article/d...

front cover of issue 18 of Lab on a Chip: Rendering of thermoresponsive array with multicoloured analytes

011

Lab on a Chip @labonachip.rsc.org · 27/08/2026

On the inside front cover of issue 17 of Lab on a Chip: Perfused brain slice-on-chip platforms: a systematic review of long-term organotypic hippocampal tissue culture. #OpenAccess from Tando Maduna, Andreas Vlachos et al. Read now: pubs.rsc.org/LC/article/d...

inside front cover of issue 17 of Lab on a Chip: Perfused brain tissue slice on chip under microscope

010

Lab on a Chip @labonachip.rsc.org · 26/08/2026

On the front cover of issue 17 of Lab on a Chip: Microfluidic rare cell analysis beyond counting: workflow design from enrichment to multi-omics. #OpenAccess from Zongjie Wang. Read now: pubs.rsc.org/LC/article/d...

front cover of issue 17 of Lab on a Chip: Purple and blue microfluidic chip with analytes in channel

000

Lab on a Chip @labonachip.rsc.org · 21/08/2026

On the inside back cover of issue 16 of Lab on a Chip: Artificial intelligence-augmented organ- and organoid-on-a-chip for drug screening. Huang Lu et al. pubs.rsc.org/LC/article/d...

inside back cover of issue 16 of Lab on a Chip: Organ-on-a-chip with AI above represented by a brain

000

Lab on a Chip @labonachip.rsc.org · 20/08/2026

On the back cover of issue 16 of Lab on a Chip: Automation-assisted human skin-on-a-chip for modeling ultraviolet-induced injury and evaluating photoprotective and regenerative modalities. YongTae Kim, Jeong-Kee Yoon et al. pubs.rsc.org/LC/article/d...

back cover of issue 16 of Lab on a Chip: Rendering of automated cellular investigation platform

020

Lab on a Chip @labonachip.rsc.org · 19/08/2026

On the inside front cover of issue 16 of Lab on a Chip: Reversible static-site PCR via dual-phase confinement in digital microfluidics. Mais J. Jebrail et al. pubs.rsc.org/LC/article/d...

inside front cover of issue 16 of Lab on a Chip: Red PCR Droplet Stabilized by Dual-Phase Confinement in Digital Microfluidics

000

Lab on a Chip @labonachip.rsc.org · 18/08/2026

On the front cover of issue 16 of Lab on a Chip: Centrifugal microfluidics for rapid target analyte quantification in airborne bioaerosols. #OpenAccess from Steve S. Kim, John A. Rogers et al. Read now: pubs.rsc.org/LC/article/d...

front cover of issue 16 of Lab on a Chip: Multicoloured centrifugal microfluidic platform surrounded by microorganisms

011

Lab on a Chip @labonachip.rsc.org · 03/08/2026

On the back cover of issue 15 of Lab on a Chip: Mechanoadaptive root growth in Medicago sativa under controlled microhydrodynamic environments. Joong Yull Park et al. pubs.rsc.org/LC/article/d...

back cover of issue 15 of Lab on a Chip: Two plants growing on glass slides

000

Lab on a Chip @labonachip.rsc.org · 03/08/2026

On the inside front cover of issue 15 of Lab on a Chip: A dual-mode vertical flow assay for species-specific identification and total bacteria load assessment from a single urine sample. #OpenAccess from Ching-Fen Shen, Chao-Min Cheng et al. Read now: pubs.rsc.org/LC/article/d...

inside front cover of issue 15 of Lab on a Chip: Vertical flow assay system with smartphone analyser

111

Lab on a Chip @labonachip.rsc.org · 29/07/2026

On the front cover of issue 15 of Lab on a Chip: Adeno-associated viral vector purification using a centrifugal microfluidic system: towards workflow automation for low-volume sample processing. #OpenAccess from Matthias Geissler et al. Read now: pubs.rsc.org/LC/article/d...

front cover of issue 15 of Lab on a Chip: Viral vector purification by centrifuge

000

Lab on a Chip @labonachip.rsc.org · 17/07/2026

On the back cover of issue 14 of Lab on a Chip: Learning-aided design of micropost arrays for optimizing interface stability and mass transport in organs-on-chips. Song Ih Ahn et al. pubs.rsc.org/LC/article/d...

back cover of issue 14 of Lab on a Chip: Mass transport in organ-on-a-chip device with analytical screens

001

Lab on a Chip @labonachip.rsc.org · 16/07/2026

On the inside front cover of issue 14 of Lab on a Chip: Microfluidic compartmentalization reveals that ferrostatin-1 restores directional mitochondrial transport in Aβ-challenged neurons. #OpenAccess from Amalia M. Dolga et al. Read now: pubs.rsc.org/LC/article/d...

inside front cover of issue 14 of Lab on a Chip: Mitochondrial rupture inside neuronal axon

000

Lab on a Chip @labonachip.rsc.org · 15/07/2026

On the front cover of issue 14 of Lab on a Chip: Auto-SELEX: a fully automated microfluidic platform for rapid discovery of high-affinity aptamers. #OpenAccess from Levent Yobas et al. Read now: pubs.rsc.org/LC/article/d...

front cover of issue 14 of Lab on a Chip: Microfluidic platform performing automated aptamer discovery

010

Lab on a Chip @labonachip.rsc.org · 08/07/2026

On the inside back cover of issue 13 of Lab on a Chip: Yield stress fluids in microfluidics: research, applications and opportunities. #OpenAccess from Hossein Rahmani & Seyed Mohammad Taghavi @ulaval.ca Read now: pubs.rsc.org/LC/article/d...

000

Lab on a Chip @labonachip.rsc.org · 06/07/2026

On the back cover of issue 13 of Lab on a Chip: Acoustofluidic separation of oblate spheroids from spheres using acoustic radiation torque and force. #OpenAccess from Seong Jae Lee, Jinsoo Park et al. Read now: pubs.rsc.org/LC/article/d...

back cover of issue 13 of Lab on a Chip: Blood cells being separated in channel passing through laser

010

Lab on a Chip @labonachip.rsc.org · 03/07/2026

On the inside front cover of issue 13 of Lab on a Chip: Acoustofluidic trapping of microparticles to axially centered wires in cylindrical microcapillaries. #OpenAccess from Steven W. Graves et al @unm.edu Read now: pubs.rsc.org/LC/article/d...

inside front cover of issue 13 of Lab on a Chip: Cyclindrical microcapillaries for trapping microparticles

011

Lab on a Chip @labonachip.rsc.org · 02/07/2026

On the front cover of issue 13 of Lab on a Chip: Development of a 16-channel solid-state nanopore array platform for integrated nanopore fabrication and ionic current measurement. Yanagi, Kiyuna, Esashika, Yanagawa, Nguyen Pham, Kawai, Ogihara, Ogino, Takeda & Uemura. pubs.rsc.org/LC/article/d...

front cover of issue 13 of Lab on a Chip: Nanopore array surrounded by analytical equipment

011

Lab on a Chip @labonachip.rsc.org · 19/06/2026

On the inside back cover of issue 12 of Lab on a Chip: A contractile force measurement system for hiPSC-derived cardiac tissue integrated with an ultrathin, stretchable nanomesh. Tetsutaro Kikuchi, Sunghoon Lee, Shinjiro Umezu et al. pubs.rsc.org/en/content/a...

inside back cover of issue 12 of Lab on a Chip: Nanomesh integrated cardiac tissue stretching between two plates

010

Lab on a Chip @labonachip.rsc.org · 18/06/2026

On the back cover of issue 12 of Lab on a Chip: Lab-on-a-chip systems for microplastic and nanoplastic sampling, detection, characterization and bioassessment. #OpenAccess from Yang Lin et al @columbiauniversity.bsky.social @universityofri.bsky.social Read now: pubs.rsc.org/en/content/a...

back cover of issue 12 of Lab on a Chip: Green laser firing into microfluidic chip against mountain lake background

010

Lab on a Chip @labonachip.rsc.org · 17/06/2026

On the inside front cover of issue 12 of Lab on a Chip: 3D stamp-integrated open-top microfluidic organ-on-a-chip for high-fidelity and functional reconstruction of vascularized microtissue models. Xiaolin Wang et al. pubs.rsc.org/en/content/a...

inside front cover of issue 12 of Lab on a Chip: Open top organ-on-a-chip with stamp above

011

Lab on a Chip @labonachip.rsc.org · 17/06/2026

On the front cover of issue 12 of Lab on a Chip: A rapid in situ synthesis of bioinspired nanoflowers on a microfluidic dipstick for point-of-care diagnosis of normoglycemic glycosuria. Zedong Nie et al. pubs.rsc.org/en/content/a...

front cover of issue 12 of Lab on a Chip: Point-of-care diagnostic smartphone

000

Lab on a Chip @labonachip.rsc.org · 08/06/2026

On the inside back cover of issue 11 of Lab on a Chip: An AI-enabled tool for quantifying overlapping red blood cell sickling dynamics in microfluidic assays. #OpenAccess from Guansheng Li, Ming Dao, George Em Karniadakis, Mengjia Xu et al @brown.edu @mit.edu Read now: pubs.rsc.org/en/content/a...

inside back cover of issue 11 of Lab on a Chip: Mesh of circulatory vessels

020

Lab on a Chip @labonachip.rsc.org · 08/06/2026

On the back cover of issue 11 of Lab on a Chip: 3D printing monolithic, multifunctional polymer acoustofluidic devices with tunable mixing and particle focusing. #OpenAccess from Tyler R. Ray et al. Read now: pubs.rsc.org/en/content/a...

back cover of issue 11 of Lab on a Chip: Close-up of micro device bathed in blue, yellow, red and green light

000

Lab on a Chip @labonachip.rsc.org · 05/06/2026

On the inside front cover of issue 11 of Lab on a Chip: Gut–liver-on-a-chip enables mechanistic study and risk assessment of drug-induced liver injury and drug–drug interactions. Xiaobing Zhou et al. pubs.rsc.org/en/content/a...

inside front cover of issue 11 of Lab on a Chip: Analytical mircochip with three wells over cellular analytes

000

Lab on a Chip @labonachip.rsc.org · 04/06/2026

On the front cover of issue 11: Bacterial extracellular vesicles indirectly destabilize a human stem cell-derived blood–brain barrier on-chip through pro-inflammatory stimulation of immune cells. Louis P. Widom et al @rittigers.bsky.social @urochester.bsky.social pubs.rsc.org/en/content/a...

front cover of issue 11 of Lab on a Chip: Rendering of cross section of blood vessel

111

Lab on a Chip @labonachip.rsc.org · 27/05/2026

On the inside front cover of issue 10 of Lab on a Chip: Numerical microfluidic chip modeling of laminar vortex dynamics induced by biomineralization in evolving porous media. #OpenAccess from Yajie Chu & Dianlei Feng. Read now: pubs.rsc.org/en/content/a...

inside front cover of issue 10 of Lab on a Chip: Artistic rendering of vortex dynamics in microfluidic chip

010

Lab on a Chip @labonachip.rsc.org · 26/05/2026

On the front cover of issue 10 of Lab on a Chip: Point of care molecular cancer diagnostics. #OpenAccess from Seemesh Bhaskar, Brian T. Cunningham et al. Read Now: pubs.rsc.org/en/content/a...

front cover of issue 10 of Lab on a Chip: Point of care unit in clinical setting with two tone colouring

000

Lab on a Chip @labonachip.rsc.org · 08/05/2026

On the back cover of issue 9 of Lab on a Chip: Multi-wavelength transparent microfluidic device for UV-visible illumination and X-ray scattering studies of photoactive systems. #OpenAccess from Benedetta Marmiroli, Sumea Klokic et al. Read now: pubs.rsc.org/en/content/a... #!divAbstract

back cover of issue 9 of Lab on a Chip: Light scattering at different wavelengths between analytes

000

Lab on a Chip @labonachip.rsc.org · 07/05/2026

On the inside front cover of issue 9 of Lab on a Chip: Smarter cell sorting: droplet microfluidics meets pick-and-place sorting. #OpenAccess from Jialan Cao, Alexander Gross et al. Read now: pubs.rsc.org/en/content/a...

inside front cover of issue 9 of Lab on a Chip: Multicoloured cells being sorted by microfluidic device

010

Lab on a Chip @labonachip.rsc.org · 06/05/2026

On the front cover of issue 9 of Lab on a Chip: Vector-free DNA transfection by nuclear envelope mechanoporation. #OpenAccess from Xiaoyun Ding et al @colorado.edu ead now: pubs.rsc.org/en/content/a...

front cover of issue 9 of Lab on a Chip: Cells porated on microchannel chip

000

Lab on a Chip @labonachip.rsc.org · 29/04/2026

On the inside back cover of issue 8 of Lab on a Chip: Multiphasic droplet microfluidics platform for controlled bacteria and mammalian cell co-culture. #OpenAccess from Ibraheem Alshareedah & Anand Kumar. Read now: pubs.rsc.org/en/content/a...

inside back cover of issue 8 of Lab on a Chip: Coculture of mammalian and bacterial cells in green/blue microfluidic device

000

Lab on a Chip @labonachip.rsc.org · 28/04/2026

On the back cover of issue 8 of Lab on a Chip: Real-time impedance-based cell migration measurements with integrated electrodes on porous membranes for next generation microphysiological systems. #OpenAccess from Darwin R. Reyes et al. Read now: pubs.rsc.org/en/content/a...

back cover of issue 8 of Lab on a Chip: Cell migration through integrated electrodes on porous membrane

010

Lab on a Chip @labonachip.rsc.org · 27/04/2026

On the inside front cover of issue 8 of Lab on a Chip: MaGIC-OT: an AI-guided optical tweezers platform for autonomous single-cell isolation in microfluidic devices. #OpenAccess from Ali Salehi-Reyhani et al @therealscientwist.bsky.social @imperialsandc.bsky.social. pubs.rsc.org/en/content/a...

inside front cover of issue 8 of Lab on a Chip: Cells being sorted on microfluidic chip with rainbow motif

000

Lab on a Chip @labonachip.rsc.org · 27/04/2026

On the front cover of issue 8 of Lab on a Chip: A tumor spheroid array chip for high-fidelity evaluation of liposomal drug delivery through the EPR effect. #OpenAccess from Jung Y. Han, Jihoon Ko et al. Read now: pubs.rsc.org/en/content/a...

Front cover of issue 8 of Lab on a Chip: Digital render of spheroid tumour chip

000

Lab on a Chip @labonachip.rsc.org · 07/04/2026

On the inside back cover of issue 7 of Lab on a Chip: Hydrogel microwell with pneumatic soft actuator for compression formation of three-dimensional cellular tissue. Yuta Kurashina et al. pubs.rsc.org/en/content/a...

inside back cover of issue 7 of Lab on a Chip: Hydrogel microwells forming 3D cellular tissue

010

Lab on a Chip @labonachip.rsc.org · 07/04/2026

On the back cover of issue 7 of Lab on a Chip: Acoustic probing of new biomarkers for rapid sickle cell disease screening. #OpenAccess from Xiaoyun Ding et al @colorado.edu Read now: pubs.rsc.org/en/content/a...

back cover of issue 7 of Lab on a Chip: Blood analysis device linked to smartphone

000

Lab on a Chip @labonachip.rsc.org · 07/04/2026

On the inside front cover of issue 7 of Lab on a Chip: Label-free monitoring of therapy response in 3D spheroids using lab-on-a-chip impedance spectroscopy. #OpenAccess from Leyla Esfandiari et al. Read now: pubs.rsc.org/en/content/a...

inside front cover of issue 7 of Lab on a Chip: Impedence spectroscopy of spheroids in microcell

000

Lab on a Chip @labonachip.rsc.org · 01/04/2026

On the front cover of issue 7 of Lab on a Chip: Microfluidic determination of minimum miscibility pressure (MMP) in dynamic CO2/n-decane flow. #OpenAccess from Junyi Yang & Peichun Amy Tsai @ualberta.bsky.social Read now: pubs.rsc.org/en/content/a...

Front cover of issue 7 of Lab on a Chip: Magnifying glass inspecting a channel on a microfluidic chip.

000

Lab on a Chip @labonachip.rsc.org · 20/03/2026

On the inside back cover of issue 6 of Lab on a Chip: Systematic characterization and mechanistic insights into ultrasonically actuated sharp-tip capillary droplet generation. Gang Li et al pubs.rsc.org/en/content/a...

000

Lab on a Chip @labonachip.rsc.org · 20/03/2026

On the back cover of issue 6 of Lab on a Chip: A high-throughput liver-kidney metabolic interaction chip for insights into the nephrotoxicity mechanisms of triptolide. Ting Liu, Guozhuang Zhang et al. pubs.rsc.org/en/content/a...

back cover of issue 6 of Lab on a Chip: High-throughput liver and kidney metabolic interaction chip

000

Lab on a Chip @labonachip.rsc.org · 19/03/2026

On the inside front cover of issue 6 of Lab on a Chip: A wearable 3D-printed hollow microneedle device for pressure-driven interstitial fluid collection and testing. Faith Inci et al. pubs.rsc.org/en/content/a...

inside front cover of issue 6 of Lab on a Chip: Hollow microneedles puncturing cross section of skin layer

000

Lab on a Chip @labonachip.rsc.org · 19/03/2026

On the front cover of issue 6 of Lab on a Chip and from our reviews issue: On-chip characterization of cell mechanics assisted by external physical fields and artificial intelligence. Xiaoming Liu, Zhuo Chen et al. pubs.rsc.org/en/content/a...

front cover of issue 6 of Lab on a Chip: Schematic wireframe view of microfluidic device in neon colour palette

121

Lab on a Chip @labonachip.rsc.org · 13/03/2026

On the inside back cover of issue 5 Engineering perfusion to meet tumor biology: are vascularized tumor-on-a-chip models ready to drive therapy innovation? #OpenAccess from Giulia Adriani et al pubs.rsc.org/en/content/a... @ccrb27.bsky.social @london-nano.bsky.social @kingscollegelondon.bsky.social

inside back cover of issue 5 of Lab on a Chip (reviews issue): Render of vascularised tumor-on-chip microphysiological system

021

Lab on a Chip @labonachip.rsc.org · 13/03/2026

On the back cover of the 2026 reviews issue of Lab on a Chip: Microfluidic shape-based separation for cells and particles: recent progress and future perspective. #OpenAccess from Jörg König, Jinsoo Park et al. Read now: pubs.rsc.org/en/content/a...

Back cover of the 2026 reviews issue of Lab on a Chip: Tree shaped channels of analyte subjected to various analytical instruments

010

Lab on a Chip @labonachip.rsc.org · 12/03/2026

On the inside front cover of Lab on a Chip's reviews issue 2026: Light driven polymer thin films as flying robotic chips in the sky. #OpenAccess from Jianfeng Yang & Hao Zeng Read now: pubs.rsc.org/en/content/a...

Inside front cover of Lab on a Chip's reviews issue 2026: Hands holding seeds being dispersed by the wind.

011