Reposted by Sergei KutseikinbioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 18/02/2026Pharmacological Inhibition of SLC33A1 Promotes Endoplasmic Reticulum Hyperoxidation and Induces Adaptive IRE1/XBP1s Signaling www.biorxiv.org/content/10.64898/20… 043
Reposted by Sergei KutseikinWiseman Lab @wisemanlab.bsky.social · 18/02/2026New preprint from @kutseikin.bsky.social showing how pharmacologic inhibition of SLC33A1 activates IRE1/XBP1s signaling. w/ @enriquesaez.bsky.social @chrisgparker.bsky.social @landerlab.bsky.social @forlilab.bsky.social & the Birsoy lab (Rockefeller) Check it out👇 www.biorxiv.org/content/10.6...biorxiv.org 087