Reposted by Krist Antunes Fernandes
Immuno-nutritionist @kristantunes.bsky.social shows how symbiotic worm colonisation of mouse mums protects offspring from viral infection (eg flu) by transmitting antibodies and metabolism-boosting microbes in milk, which activate antiviral genes in barrier cells in the pup's lung. #2026SDB
Paper⤵
cell.com
Maternal helminths rewire the microbiota to promote offspring antiviral immunity
Fernandes et al. show that maternal helminths, long-standing mammalian partners, confer
antiviral immunity to offspring via the microbiota-derived metabolite indole-3-propionic
acid (IPA). This work r...