DNA polymerase beta (POLB) is required for rapid rates of cellular DNA base excision repair (BER). However, the reason for this requirement is unclear, because other DNA polymerases can replace POLB i...

Break-induced replication (BIR) is mediated by DNA polymerase d (Pol d). Here, the authors identify a phospho-activated RPA-binding module in Pol d which promotes BIR efficiency, providing a paradigm ...

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Abstract. Flap endonuclease 1 (FEN1)-dependent long-patch repair has been considered a minor sub-pathway of DNA single-strand break repair (SSBR), activate

Oncogene - EWS::FLI1-DHX9 interaction promotes Ewing sarcoma sensitivity to DNA topoisomerase 1 poisons by altering R-loop metabolism