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Kazuki Yoshida

@kaz-yos.bsky.social
1K followers 976 following 175 posts

Father in Training | #Rheumatology & Immunology Clinical Development | Pharmacoepidemiology | www.linkedin.com/in/kazyos

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Kazuki Yoshida @kaz-yos.bsky.social · 03/10/2026
Progresses in the CLE land www.lupustherapeutics.org/late-breakin... www.dermatologytimes.com/view/daxdili...
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Kazuki Yoshida @kaz-yos.bsky.social · 20/09/2026
Understandable explanation on the Hugging Face hack by OpenAI experimental agents m.youtube.com/watch?v=luXn...
m.youtube.com
The Doomsday Cult Inside OpenAI
YouTube video by Patrick Boyle
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Lupus Foundation of America @lupus.org · 01/09/2026
Novartis and Bristol Myers Squibb have paused their CAR-T trials for #lupus and other autoimmune diseases to review safety concerns. CAR-T remains experimental, and continued research is needed to understand its benefits and risks. Read the announcement: buff.ly/QJBbN7L
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Kazuki Yoshida @kaz-yos.bsky.social · 28/08/2026
Lunar eclipse has began in New England. The photo is bad but the left lower corner is dark
Lunar eclipse
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Rheum Cat @rheumcat.bsky.social · 12/08/2026
The one eclipse I ever saw was pretty cool
Eclipse shadows in a heart pattern on a purple skirt Eclipse shadows in a heart pattern on a white paper Eclipse shadows in a heart pattern on a white paper
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Kazuki Yoshida @kaz-yos.bsky.social · 12/08/2026
Partial eclipse (pinhole observation)
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Kazuki Yoshida @kaz-yos.bsky.social · 10/08/2026
I just found this strange structure on my corn. This turns out to be a male flower structure erroneously developing on a female flower structure (they are usually separated). www.farmprogress.com/corn/odd-sha...
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Kazuki Yoshida @kaz-yos.bsky.social · 17/06/2026
Cell Therapy in Rheumatology: CAR-T vs Regulatory T Cells pca.st/episode/6f59... explore CAR-T therapy, immune resets, regulatory T cells, relapse risk, and the future of rheumatology with Dr. Georg Schett
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Greg Folkers @gregfolkers.bsky.social · 01/06/2026
ScienceInsider: HHS is now weighing in on science in NIH grants Staffers say comments coming after NIH’s own approvals are overriding peer review by Jocelyn Kaiser @jocelynkaiser.bsky.social @science.org bit.ly/4343TtT
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Kazuki Yoshida @kaz-yos.bsky.social · 30/05/2026
open.substack.com/pub/autoimmu...
open.substack.com
The (sc)Pen is Mightier Than the (iv)Cord
SC anifrolumab hits the market
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Kazuki Yoshida @kaz-yos.bsky.social · 23/04/2026
The End pca.st/episode/d9c3...
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Kazuki Yoshida @kaz-yos.bsky.social · 21/04/2026
FDA accepts Roche application for Gazyva/Gazyvaro in common lupus treatment | Seeking Alpha
seekingalpha.com
FDA accepts Roche application for Gazyva/Gazyvaro in common lupus treatment
Roche’s Gazyva lupus FDA filing: B-cell anti-CD20 could be new SLE standard of care.
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Kazuki Yoshida @kaz-yos.bsky.social · 04/04/2026
At #rockspotclimbing South Boston
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Kazuki Yoshida @kaz-yos.bsky.social · 26/03/2026
Wealth, shown to scale eattherichtextformat.github.io/1-pixel-weal...
eattherichtextformat.github.io
Wealth, shown to scale
Wealth inequality in the United States is out of control. Here we visualize the issue in a unique way.
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Kazuki Yoshida @kaz-yos.bsky.social · 12/03/2026
open.substack.com/pub/autoimmu...
open.substack.com
Pipeline Monitor: Avacopan Under Fire & B Cells are Having a Moment
But emerging indications for JAK/TYKs may be the story that lasts
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Kazuki Yoshida @kaz-yos.bsky.social · 12/03/2026
The train is on service now www.youtube.com/watch?v=vAQf...
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Kazuki Yoshida @kaz-yos.bsky.social · 05/03/2026
Claude Code: This is indeed interesting. Claude examined the tableone codebase for TODO comments and implemented one of them. (I’m not going to merge this as it breaks backward compatibility)
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Kazuki Yoshida @kaz-yos.bsky.social · 22/01/2026
‘If we’re not at the table, we’re on the menu’ FULL SPEECH: Canada’s PM Carney Says US-Led World Order Is Breaking at World Economic Forum | AC1G - YouTube www.youtube.com/watch?v=dTvF...
youtube.com
Your browser is up to date
You can use YouTube's latest features!
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Kazuki Yoshida @kaz-yos.bsky.social · 20/01/2026
Reproducible Research Workflow shibakoichiro.github.io/20260120-rep...
shibakoichiro.github.io
Reproducible Research Workflow
BUSPH EP860
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Elliott Payne @elliottpayne.org · 19/01/2026
This is what happened in our neighborhood yesterday. ICE snatched a human being off of our streets, roughed them up badly, and then pepper sprayed legal observers as they documented it all. This is a daily occurrence happening all throughout Minnesota right now.
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Kazuki Yoshida @kaz-yos.bsky.social · 19/01/2026
DMOAD has arrived!?: Biosplice Announces the Submission of its New Drug www.globenewswire.com/news-release...
globenewswire.com
Biosplice Announces the Submission of its New Drug Application (NDA) to the FDA for Lorecivivint (LOR) to Treat Knee Osteoarthritis
Biosplice announces submission of new drug application to US FDA for treatment of knee osteoarthritis...
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James Ball @jamesrball.com · 03/01/2026
Marco Rubio is reportedly saying Maduro will stand trial in US courts. Which means it’s now the US administration’s position that US courts can hold foreign presidents, but not the US president, accountable for crimes.
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Kazuki Yoshida @kaz-yos.bsky.social · 31/12/2025
The CDC Shooting Isn't What Broke Me | MedPage Today www.medpagetoday.com/opinion/seco...
medpagetoday.com
Opinion | The CDC Shooting Isn't What Broke Me
Continuing to show up to work at an agency I no longer trust is devastating
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Phil Rocco @philiprocco.bsky.social · 26/12/2025
The Wisconsin component of the analysis here is revealing. Evidence is consistent with DOGE strategically delaying contract terminations in WI until after the 2025 state Supreme Court elections to mitigate electoral risk.
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Kazuki Yoshida @kaz-yos.bsky.social · 22/12/2025
New Targeted Therapies for Sjögren’s Disease and Diagnostic Advances in 2025 | Vumedi
vumedi.com
New Targeted Therapies for Sjögren’s Disease and Diagnostic Advances in 2025
A video from Robin Dore, posted on Dec 16, 2025.
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Kazuki Yoshida @kaz-yos.bsky.social · 11/12/2025
Korean plush toys for kids
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Scott Gottlieb, MD @scottgottliebmd.bsky.social · 03/12/2025
12 former commissioners of the FDA came together to write a Perspectives piece for the New England Journal of Medicine; raising our concerns about recent changes to vaccine approval policy at the FDA and its implications for patients and public health.
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Kazuki Yoshida @kaz-yos.bsky.social · 03/12/2025
The Thinking Game | Full documentary | Tribeca Film Festival official selection www.youtube.com/watch?v=d95J... Really interesting documentary I randomly found during air travel
youtube.com
The Thinking Game | Full documentary | Tribeca Film Festival official selection
The Thinking Game takes you on a journey into the heart of DeepMind, capturing a team striving to unravel the mysteries of intelligence and life itself. Filmed over five years by the award winning…
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Kazuki Yoshida @kaz-yos.bsky.social · 29/11/2025
The rapid growth in Mendelian randomization studies | European Journal of Epidemiology link.springer.com/article/10.1...
link.springer.com
The rapid growth in Mendelian randomization studies - European Journal of Epidemiology
European Journal of Epidemiology -
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Damien C-C @dccc-phd.bsky.social · 27/11/2025
"More than 70 percent of the MBTA’s rapid transit stops [...] have at least one Bluebikes docking station within 200 meters. With this overlap, a Bluebikes ride can cover the first or last mile of a multimodal commute to extend the range of MBTA trips [...]"
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Kazuki Yoshida @kaz-yos.bsky.social · 27/11/2025
E-bikes are supercharging the Bluebikes system - and that's a good thing   - CommonWealth Beacon commonwealthbeacon.org/opinion/e-bi...
commonwealthbeacon.org
E-bikes are supercharging the Bluebikes system - and that's a good thing   - CommonWealth Beacon
BLUEBIKE RIDERSHIP has soared in Greater Boston. While there is no single solution to our many transportation challenges, the growing popularity of
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Kazuki Yoshida @kaz-yos.bsky.social · 09/11/2025
Obinutuzumab, REGENCY, & Updates in Lupus Nephritis, With Brad Rovin, MD pca.st/episode/ef70...
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FactPost @factpostnews.bsky.social · 05/11/2025
Democrat Michelle Wu has been re-elected Mayor of Boston.
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Rheum Cat @rheumcat.bsky.social · 25/10/2025
What target cell(s) important for rheum disease? -T cells: because lots of antimetabolites we use work here -B cells: but would this only work for RTX responsive diseases? -plasma cells? -myeloid cells? Steroids, IL-1i, IL-6i are targeting here #ACR25
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Rheum Cat @rheumcat.bsky.social · 25/10/2025
Drug development looks simpler from the onc viewpoint than rheum -mechanisms better understood -dx is done with bx -trials have uniform criteria -risk tolerance is different (clinicians and patients) -trying new things is more accepted #ACR25
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Rheum Cat @rheumcat.bsky.social · 25/10/2025
Marcela Maus took the BCRC to the finish line by talking about CAR-T study design for rheum with lessons learned from onc #ACR25
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Rheum Cat @rheumcat.bsky.social · 26/10/2025
#ACR25 - Sunday Plenary I 🌟
cat head logo
#ACR25
American College of Rheumatology Convergence - Chicago
Plenary highlights
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Rheum Cat @rheumcat.bsky.social · 26/10/2025
Abs 0772 Petri et al ❓ Are guidelines for kidney bx missing LN? They use a threshold of UPCR >= 0.5g/g In this study they looked at patients with SLE + UPCR 0.25-0.44g and did kidney bx. 👨‍👨‍👦 N=28; 20 ultimately diagnosed with LN. 🤔 Should the threshold for kidney bx in SLE be lowered? #ACR25
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Rheum Cat @rheumcat.bsky.social · 26/10/2025
Abs 0776 Schmidt et al 💊 2 year outcomes of the SELECT-GCA RCT studying UPA 👨‍👨‍👦 N=181 re-randomized to continue UPA vs switch to PBO 69% continuing UPA maintained remission vs 29% switched to PBO UPA 15mg dose was a/w lower frequencies of serious infx but higher herpes zoster #ACR25
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public health guy @publichealthguy1.bsky.social · 26/10/2025
apropos of nothing
defendpublichealth.org
The Cruelty Is the Point: Pediatric Cancer trials eliminated | Defend Public Health
This week, Trump announced funding for AI-driven pediatric cancer research. But don't be fooled. He's already cancelled longstanding research efforts into pediatric cancers, leaving kids and their fam...
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Josh Marshall @joshtpm.bsky.social · 26/10/2025
This is several days old. But amidst so much else id missed it. That’s a stunning number. No wonder they about-faced. Reminder of the power of consumers in oligarch era, not subject to the same kind of targeting.
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Michael Friendly @datavisfriendly.bsky.social · 26/10/2025
#TodayinHistory #dataviz #OTD 📊 💀Oct 25, 1914 Wilhelm Lexis died in Gottingen, Germany 🇩🇪 1875: The Lexis diagram, showing relations among age (cohort), calendar time, and life spans of individuals simultaneously. Revolutionized demography, making key variables visible
Diagram showing the idea behind the lexis diagram. A grid of Age by Year showing diagonals of CohortSchematic diagram of a Lexis Diagram. Y axis is Age, X is calendar year. A blue diagonal gives the cohort of people born in a given year over timeBlack/white photo of Wilhelm Lexis
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Ashton Pittman @ashtonpittman.bsky.social · 26/10/2025
Monstrous.
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MeidasTouch @meidastouch.com · 20/10/2025
JUST IN: The White House has begun DEMOLISHING portions of the East Wing of the White House to build Trump’s $250 million ballroom — despite earlier claiming it wouldn’t “interfere” with the existing White House structure. (Washington Post)
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Hillary Rodham Clinton @hillaryclinton.bsky.social · 21/10/2025
It’s not his house. It’s your house. And he’s destroying it.
Washington Post: White House begins destroying East wing facade to build Trump’s ballroom
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Angry @angrystaffer.bsky.social · 21/10/2025
The White House is asking people not to share pictures of the East Wing because it’s even worse today.
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SWA @swalexander.bsky.social · 14/02/2025
Efficacy and Safety of Obinutuzumab in Active Lupus Nephritis www.nejm.org/doi/10.1056/...
nejm.org
Efficacy and Safety of Obinutuzumab in Active Lupus Nephritis | NEJM
Obinutuzumab, a humanized type II anti-CD20 monoclonal antibody, provided significantly better renal responses than placebo in a phase 2 trial involving patients with lupus nephritis receiving stan...
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Lupus Foundation of America @lupus.org · 20/10/2025
BREAKING NEWS: The FDA has approved Gazyva® (obinutuzumab) for the treatment of adults with #lupus nephritis. Gazyva is the fourth therapy for lupus to receive regulatory approval since 2011. Read the announcement: buff.ly/81tYgo7
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Julia M. Rohrer @dingdingpeng.the100.ci · 06/10/2025
Happy to announce that I'll give a talk on how we can make rigorous causal inference more mainstream 📈 You can sign up for the Zoom link here: tinyurl.com/CIIG-JuliaRo...
Causal inference interest group, supported by the Centre for Longitudinal Studies

Seminar series
20th October 2025, 3pm BST (UTC+1)

"Making rigorous causal inference more mainstream"
Julia Rohrer, Leipzig University

Sign up to attend at tinyurl.com/CIIG-JuliaRohrer
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Anonymous @youranoncentral.bsky.social · 19/10/2025
World War 2 veterans, the original antifa, took part in the nationwide protests against the fascist Trump regime. #3E #NoKings #50501Movement #indivisible #wearetheflood
Veteran holds sign
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