The RNA-binding protein ZFP36L2 mediates stress-adaptive plasticity in intestinal regeneration and colorectal cancer metastasis.

Metient is a statistical framework that infers patterns of metastatic spread and reconstructs cancer migration histories.

The chromatin-remodelling enzyme ATRX and the transcription factor HNF4A are identified as pivotal regulators of colonic epithelial identity, with roles in metastasis in colorectal cancer.

Peritoneal carcinomatosis is a common yet deadly manifestation of gastrointestinal cancers, with few effective treatments. To identify targetable determinants of peritoneal metastasis, we focused on a...

Colorectal cancer metastasis involves dramatic plasticity and loss of PROX1-mediated repression of non-intestinal lineages.

Nature Reviews Gastroenterology & Hepatology - Non-canonical metastatic colorectal cancer