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Shubharthi Kar

@karnephro.bsky.social
883 followers 320 following 57 posts

Nephrologist #Bangladesh #ISNeducation #SOME Social Media Team Member #SARB #SACA member International Society of Hypertension

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Reposted by Shubharthi Kar
Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 05/12/2025
Another G-force molecule GLP + glucagon agonist #pemvidutide in MASH Resolution of MASH, fibrosis impact not seen at this time www.thelancet.com/journals/lan... in @thelancet.com How long till someone (?Pfizer) gobbles up Altimmune? @rnflex.bsky.social
Figure 2. Primary endpoints
(A) The least-squares mean proportion of patients with resolution of MASH without worsening of fibrosis after 24 weeks of treatment; error bars represent SE; MASH resolution was defined as at least a 2-point reduction in NAS (scale of 0 to 8, with higher scores indicating more severe disease), no hepatocyte ballooning, and a score of 0 or 1 in the lobular inflammation component of the score, without worsening fibrosis. (B) The least-squares mean proportion of patients with liver fibrosis improvement without worsening of MASH after 24 weeks of treatment, defined as the proportion of patients achieving at least a one-stage improvement in liver fibrosis without worsening of NAS; error bars represent SE. A composite strategy was employed that considered patients with missing outcomes due either to missing biopsies or treatment discontinuations as non-responders. Data were analysed with the use of the chi-square test. MASH=metabolic dysfunction-associated steatohepatitis. NAS=non-alcoholic fatty liver disease activity score.
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American Journal of Kidney Diseases @ajkd.bsky.social · 04/12/2025
EDITORIAL: Breaking Down Barriers to Reproductive Health Care in CKD bit.ly/48wkB7l (FREE)
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Shubharthi Kar @karnephro.bsky.social · 03/12/2025
Happy to share that our abstract has been accepted for upcoming #ISNWCN
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Reposted by Shubharthi Kar
Nephrology Journal Club @nephjc.bsky.social · 01/12/2025
Maybe the most shocking study from #KidneyWk. 🐚From the depths of the oceans to #BlueSky, we're discussing PISCES 🐟 12/2/25 9pm EST. #NephJC Are you hooked🪝on fish oil for CV disease in ESRD, or are you throwing it back 🌊? www.nephjc.com/news/pisces-fishoil
nephjc.com
Fish Oil in Dialysis: A Big Catch or an Empty Net — NephJC
Holy Mackerel! This week we will discuss fish oil use in maintenance hemodialysis patients. Could this be the one thing that bends the curve on CV mortality, or is it just a red herring?
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Shubharthi Kar @karnephro.bsky.social · 23/11/2025
My conference talk at the Kidney Foundation Dhaka, Bangladesh, concluded with an invitation to register for the upcoming WCN 2026, to be held from March 28–31 in Yokohama, Japan. 🐦‍⬛ Please note that the deadline for Early Bird Registration is January 24, 2026. #ISNWCN #ThisisISN
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kireports.bsky.social @kireports.bsky.social · 29/10/2025
#Exome-wide Analysis Identifies a Rare #EXD3 Missense Variant Associated With #Diabetic #Kidney Disease #VisualAbstract by Stephanie Torres www.kireports.org/article/S2468-024… Niina Sandholm
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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 18/11/2025
The #NephJC summary and VA are live www.nephjc.com/news/atacice... Excellent fast work from @notjustdialysis.bsky.social and @salinesolut.bsky.social Atacicept in IgAN
nephjc.com
Attacking the Origin of IgAN: ORIGIN3 and Atacicept — NephJC
This week, we will discuss the phase 3 ORIGIN3 trial of atacicept, an APRIL/BAFF inhibitor for use in IgAN.
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ISNkidneycare @theisn.org · 14/11/2025
1a/🌞Hello everyone, welcome to the #WorldDiabetesDay #skeetorial on behalf of @theisn.org @who.int ⁉️Let us begin with a quiz 🎊Do you know the theme of World Diabetes Day 2025? a/ Breaking barriers, bridging gaps b/ Family and diabetes c/ Access to diabetes care d/ Diabetes across life stages
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ISNkidneycare @theisn.org · 17/10/2025
📣 Save the date! 🗓️ October 28, 12pm EST Join us for a Space on Tropical AKI, Part 2 🎧 Set your reminder twitter.com/i/spaces/1gq... 🧠 Before the session, test your knowledge! Take the quiz 👉 theisn.outgrow.us/Tropical_AKI Let’s see how much you know about Tropical AKI before the experts dive in! 💪🌴
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Nephrology Journal Club @nephjc.bsky.social · 15/10/2025
🎨Beautiful visual abstract by @msocomd.bsky.social #NephJC
nephjc.com
Protein supplementation in CKD: The Visual Abstract — NephJC
We like protein, or do we? Low protein, high protein, supplements…what’s a nephrologist to do?
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Shubharthi Kar @karnephro.bsky.social · 15/10/2025
Shubharthi from Bangladesh. No COI. #NephJC
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Preeclampsia Foundation @preeclampsia.org · 05/09/2025
September is #PCOSAwarenessMonth. Women who have polycystic ovary syndrome #PCOS have a risk of developing #preeclampsia in their #pregnancy. Learn more here: www.preeclampsia.org/faqs
preeclampsia.org
Preeclampsia - FAQs
Preeclampsia Treatment, Eclampsia, Eclampsia Treatment, Toxemia, PET and PIH, HELLP Syndrome, Causes Preeclampsia, Preeclampsia Affect Pregnancy, Preeclampsia Affect the Baby
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ISNkidneycare @theisn.org · 28/07/2025
🎬 Share your story! Submit your short film for the 2026 #ISNFilmEvent — real stories from those affected by kidney disease and their care teams. Open to ISN members. Deadline: Nov 5 (midnight CET). 🎥 Info & submissions ➡️ lite.spr.ly/6... #ThisIsISN #ISNWCN
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ISNkidneycare @theisn.org · 16/07/2025
1/ July 16 is #WorldSnakeDay - raising awareness of the incredible diversity of snakes and their vital role in our ecosystems. But did you know snakebites can also cause acute kidney injury? Join me, Dr. Fong Voon Ken, as we discuss their impact, management, and the need for awareness.
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ISNkidneycare @theisn.org · 07/07/2025
𝗡𝗘𝗪 𝗥𝗘𝗦𝗢𝗨𝗥𝗖𝗘 𝗔𝗟𝗘𝗥𝗧: Download our #ADPKD infographic for a quick overview of diagnosis, delaying progression, complications & more. A handy resource for clinicians and patients alike! ⬇️https://www.theisn.org/wp-content/uploads/2025/07/ADPKD-Infographic.pdf
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ISNkidneycare @theisn.org · 08/07/2025
📢 The kidney community urges UN Member States to include kidney disease in the 2025 Political Declaration on NCDs & Mental Health. 🧬 850M affected 📈 5th leading cause of death by 2050 💡 Early care = 45% cost savings 📄 Read the letter: www.theisn.org/wp-co... #KidneyHealthMatters #HLM4 #NCDs
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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 06/07/2025
Interesting data from Alberta www.kidney-international.org/article/S008... in @kidneyint.bsky.social GFR < 15 is classified as ‘kidney failure’ in most studies - but about a third of them die before starting RRT. Is that glass half full or half empty? 🥃 #NephSky
Visual abstract - still needs work since KI doesn’t get professionals to do it! 🤷🏽‍♂️
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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 02/07/2025
We don’t get to discuss every important study that comes out on #NephJC Hence #NephJCShorts www.nephjc.com/news/nephjc-...
nephjc.com
Introducing NephJC Shorts — NephJC
In just over a decade of critical appraisal on NephJC, we have done several experiments. Some of them have worked out phenomenally well, such as the Freely Filtered podcast. Others were not ready for ...
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
⚡️Let’s have a closer look at the associations of each of these antigens #ECNeph @arvindcanchi.bsky.social indianjnephrol.org/an-updated-r...
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
Now that’s a roll! Thanks for joining tonight’s #ECNeph discussion @theisn.org @myadla.bsky.social @dramiliflores.bsky.social @arvindcanchi.bsky.social
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
⚡️PLA2R antibody seropositivity doesn’t mean that we do not investigate for underlying malignancies. Here is a Case Report showing PLA2rAb MN having Carcinoma Oesophagus #ECNeph @theisn.org @myadla.bsky.social @dramiliflores.bsky.social @arvindcanchi.bsky.social
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
KDIGO recommends Population and Age-appropriate Screening for malignancies irrespective of antigen status #ECNeph @theisn.org @myadla.bsky.social @dramiliflores.bsky.social @arvindcanchi.bsky.social
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
KDIGO Approach When to Biopsy in MN patients #ECNeph @theisn.org @myadla.bsky.social @dramiliflores.bsky.social @arvindcanchi.bsky.social @rheaultm.bsky.social
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
3 approaches suggested by the Mayo clinic consensus report 1. Targeted approach: Perform antigen testing based on clinical disease association Cont #ECNeph www.kidney-international.org/article/S008...
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
Here’s a timeline of the auto-antigens found in MN #ECNeph @theisn.org @myadla.bsky.social @dramiliflores.bsky.social @arvindcanchi.bsky.social indianjnephrol.org/an-updated-r...
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
👉 🫣 Can IF differentiate from Primary and Secondary MN? IgG 4 is the dominant class in primary MN 👉 IgG1,IgG2, IgG3 are dominant Immunoglobulins in Secondary MN #ECNeph @theisn.org @myadla.bsky.social @dramiliflores.bsky.social @arvindcanchi.bsky.social
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
👉 MN is a pattern of glomerular injury 👉 Deposition of immune complex along subepithelial aspect of GBM 👉 On Light Microscopy GBM is thickened. GBM spikes or holes can be seen 👉 IHC/IF shows IgG with C3 along capillary wall #ECNeph @theisn.org @dramiliflores.bsky.social @arvindcanchi.bsky.social
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
👉 5-22 % of Adults having Membranous Nephropathy had been diagnosed malignancy within a few years of the MN Diagnosis 👉 Lung, Colon, Breast, Stomach, Prostate cancers are commonest www.kidney-international.org/article/S008... #ECNeph @theisn.org @myadla.bsky.social @dramiliflores.bsky.social
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
Membranous Nephropathy and Malignancy — a deadly duo ☠️ 👉 Let’s start with some trivia ❓How many older adults develop malignancy post diagnosis of Membranous Nephropathy? A. < 1% B. 5% - 22% C. 30% - 40% D. > 50% #ECNeph @theisn.org @myadla.bsky.social @dramiliflores.bsky.social
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
❓ How do we treat cancer associated MN? 👉 RAAS Inhibition 👉 Statin 👉 Anticoagulants as needed 👉 Specific treatment for cancer #ECNeph @theisn.org @myadla.bsky.social @dramiliflores.bsky.social @arvindcanchi.bsky.social
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
Different types of tumor secrete different types of antigen. Here is the proposed mechanism of malignancy associated MN. #ECneph @dramiliflores.bsky.social @myadla.bsky.social @theisn.org www.frontiersin.org/journals/med...
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
🫣 So, let us now reveal the diagnosis. It is malignancy associated Membranous Nephropathy 👉 The association between malignancy and MN was first described in 1968 ⚡️They also gave the 4 stages of MN #ECNeph @theisn.org @myadla.bsky.social @dramiliflores.bsky.social @arvindcanchi.bsky.social
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
#ECneph
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Shubharthi Kar @karnephro.bsky.social · 30/06/2025
Hello Shubharthi ,From Sylhet, Bangladesh .Thank you @theisn.org for selecting our case from #Bangladesh No COI #ECneph
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Milagros Flores @dramiliflores.bsky.social · 30/06/2025
🧪 Proteinuria: Not a Walk in the Park 👣 Could this be more than just "nephrotic syndrome"? 🕵️ 🗓️ Join us #ECNeph Chat on Bluesky 🕛 30th June 2025, 12 PM EST @dramiliflores.bsky.social @karnephro.bsky.social @theisn.org #NephSky #MedSky @theisn.org
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ISNkidneycare @theisn.org · 30/06/2025
⏳ 60 min to go! 👣 Let’s walk through proteinuria findings 🧪🌳 🗓️ Join today for our #ECNeph Case Discussion 🕛 30th June 2025 at 12 PM EST @dramiliflores.bsky.social @karnephro.bsky.social Are you ready? #MedSky #NephSky
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ISNkidneycare @theisn.org · 25/06/2025
"Just two months after my ISN Fellowship, I coordinated our first kidney transplant. Without an HLA lab, I personally took the samples to Cairo for testing." Fatiu Arogundade, ISN Fellow (2001–2002) lite.spr.ly/6... #ISNFellowship40Years
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ISNkidneycare @theisn.org · 27/06/2025
🎬 Share your story! Submit your short film for the 2026 #ISNFilmEvent — real stories from those affected by kidney disease and their care teams. Open to ISN members. Deadline: Nov 5 (midnight CET). 🎥 Info & submissions ➡️ lite.spr.ly/6... #ThisIsISN #ISNWCN
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ISNkidneycare @theisn.org · 26/06/2025
🚨 Cardiorenal Syndrome (CRS): A Deadly Duo 🚨 Did you know the heart & kidneys are so intertwined that dysfunction in one can wreak havoc on the other? Let's dive into CRS today. A lucid read for every nephrology & cardiology fellow 🫀🩺 #MedTwitter #ISNTweetorial
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ISNkidneycare @theisn.org · 10/06/2025
📢 𝗡𝗘𝗪 𝗥𝗘𝗦𝗢𝗨𝗥𝗖𝗘 𝗔𝗟𝗘𝗥𝗧: A practical toolbox to help you start & sustain early CKD detection and intervention programs. Includes key principles, processes, and building blocks to guide effective implementation and long-term success. ➡️ Start improving kidney health today! lite.spr.ly/6002yVne
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Shubharthi Kar @karnephro.bsky.social · 29/05/2025
When you must do a CKD screening while your patient planning for pregnancy? This slide is from today's ISN-KDIGO Webinar
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Shubharthi Kar @karnephro.bsky.social · 16/05/2025
Thanks a lot for the appreciation #WorldKidneyDay
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Shubharthi Kar @karnephro.bsky.social · 14/05/2025
My Meeting with Md Mohiuddin Al Helal, Senior Assistant Secretary ,Ministry of Health and Family Welfare,Bangladesh on Guatemala resolution. He is one of the team member who will be attending #WHA78 representing Bangladesh. #ThisisISN
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Shubharthi Kar @karnephro.bsky.social · 14/05/2025
Shubharthi from Bangladesh No COI. #NephJC
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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 12/05/2025
There you have it: BEDMED published in @jama.com jamanetwork.com/journals/jam... h/t @drjmluther.bsky.social No difference in bedtime versus morning BP meds - as expected #NephSky #Hypertension 1/
Figure of survival curve showing no difference
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Shubharthi Kar @karnephro.bsky.social · 08/05/2025
Happy to share our Latest Article "Navigating the Complexities of ESKD from Risk Factors to Outcome : Insights from the UK Biobank Cohort" Published in the #BMC #Nephrology. 👉Early Onset Diabetes and Hypertension heighten ESKD Risk when combined with Poor Glycemic Control
bmcnephrol.biomedcentral.com
Navigating the complexities of end-stage kidney disease (ESKD) from risk factors to outcome: insights from the UK Biobank cohort - BMC Nephrology
Background The global prevalence of end-stage kidney disease (ESKD) is increasing despite optimal management of traditional risk factors such as hyperglycaemia, hypertension, and dyslipidaemia. This s...
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American Journal of Kidney Diseases @ajkd.bsky.social · 04/05/2025
AJKD Atlas of Renal Pathology: Crystalglobulin-Induced Nephropathy bit.ly/41jvO7T (FREE) #RenalPath Image: Large bright eosinophilic crystals within glomerular capillaries (arrow, Jones silver stain)
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Swetha Kanduri @swethakanduri.bsky.social · 02/05/2025
Roger Rodby highlighting PO4 Reabsorption and TumorInduced osteomalacia causing elevated Po4wasting
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ASN Publications @asnpublications.bsky.social · 01/05/2025
The May issue of JASN is now available online! Topics covered this month include: - Anticoagulation for Atrial Fibrillation with Kidney Failure - Sotagliflozin in Type 1 Diabetes - and more Check out the issue here: journals.lww.com/jas... #ASNJASN
May 2025 cover of JASN
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