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Karla Satchell

@karlasatchell.bsky.social
468 followers 246 following 31 posts

Northwestern University Microbiology Professor studying Vibrio toxins, Structural Biology, COVID and RAS degraders. Supporting women as leaders in Science.

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Reposted by Karla Satchell
Scicommpoetmom @krosejutras.bsky.social · 30/07/2026
Kristin Rose Jutras 38m Devastated to share that my husband, @jutraslab.bsky.social, passed away. People are writing fake obituaries online/sharing on social media that Brandon died of Lyme disease. This is not true and is an affront to everything Brandon stood for as a scientist: the truth.
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Karla Satchell @karlasatchell.bsky.social · 29/06/2026
The 4th Lakeside Protein Toxins and Effectors 2026 Conference (#LakesidePTE) is coming October 12-15! Early registration July 6 deadline at $800 ($700 student) just 1 week away. Come learn about mechanism of action microbial effectors and how bacterial compete. Come join our growing community!
event.fourwaves.com
Lakeside Protein Toxins and Effectors 2026
Join Lakeside Protein Toxins and Effectors 2026, October 12-15, 2026. Learn more on Fourwaves.
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Karla Satchell @karlasatchell.bsky.social · 15/06/2026
At my last study section, I was called out by SRO for commenting on information not found in the application. So accessing this info is technically not allowable. Better suggestion is take the time to update biosketch narratives for each application to help reviewers
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Karla Satchell @karlasatchell.bsky.social · 10/06/2026
Hey, if you enjoyed the session @asm.org ASM Microbe on toxins and effectors with me, @lawrenzlab.bsky.social and Matthias Macher, join us for more at Lakeside PTE conference Oct 12-15 in western Mass, chair is Min Dong. #toxins #cryoEM #vibrio #microbiology event.fourwaves.com/lakesidepte2...
event.fourwaves.com
Lakeside Protein Toxins and Effectors 2026
Join Lakeside Protein Toxins and Effectors 2026, October 12-15, 2026. Learn more on Fourwaves.
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Reposted by Karla Satchell
Matthew Lawrenz @lawrenzlab.bsky.social · 19/05/2026
The M&I Department is looking for a new faculty member with a passion for teaching graduate and medical students to join us at UofL - see the link 👇. We have a thriving collegial department in a great city. Email me if you have questions. I will also be at Microbe in June to talk more. Join us😀.
myworkday.com
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Karla Satchell @karlasatchell.bsky.social · 23/04/2026
This week’s NEJM case study. I know what it is. www.nejm.org/doi/10.1056/...
nejm.org
Vibrio vulnificus Necrotizing Soft-Tissue Infection | NEJM
A 74-year-old man presented with a painful laceration on his leg that he had sustained 3 days earlier in waters off the Gulf Coast of Florida. Ecchymosis, swelling, and crepitus were observed in th...
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Karla Satchell @karlasatchell.bsky.social · 23/04/2026
Great article on Vibrio vulnificus. apple.news/A22iml4UESBq...
apple.news
A deadly bacteria is creeping up the Atlantic Coast. How worried should you be? — Grist
Bailey Magers and Sunil Kumar cut strange figures on Pensacola Beach. Bags of disinfectant solution surrounded them on the white sand; their gloved hands juggled test tubes while layers of rubber and ...
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Karla Satchell @karlasatchell.bsky.social · 02/03/2026
We are on the move and this year will be held in beautiful Southbridge, Massachusetts at the height of leaf changing season. Conference is organized by toxin biologists for the toxin biology community. Come join us!
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Karla Satchell @karlasatchell.bsky.social · 02/03/2026
Announcing the 4th Lakeside Conference on Protein Toxins and Effectors 2026 Registration/Abstract Submission is OPEN (#lakesidePTE)! Come join this premier event on the structure, biochemistry, and cell biology of Microbial Protein Toxins Oct 12-15, 2026. event.fourwaves.com/lakesidepte2...
Conference banner showing trees with leafs changing colors.
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Karla Satchell @karlasatchell.bsky.social · 20/02/2026
I thought that was Nature group journals. Don’t you already work for that publication? Academics pay thousands and 10,000+ to publish in Nature publications. Can’t you just ask the editor one desk over?
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Karla Satchell @karlasatchell.bsky.social · 15/02/2026
Quote from Paper “This trend raises questions about whether research papers can remain a reliable method for sharing scientific progress.”
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Karla Satchell @karlasatchell.bsky.social · 25/08/2025
Finally, I want to inform readers that my lab has been at the forefront for >15 years on understanding how these bacteria cause disease. However, we are struggling because, as a Northwestern Faculty member, my grants to study these infections have been frozen since March. Please Support Science!
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Karla Satchell @karlasatchell.bsky.social · 25/08/2025
Studies from my group have shown that Vibrio vulnficus bacteria from around the phylogenetic tree can cause infections in humans. So there are not good Vv and bad Vv...they are all bad. Just some may be much worse. journals.asm.org/doi/10.1128/...
journals.asm.org
Genetic Divergence of Vibrio vulnificus Clinical Isolates with Mild to Severe Outcomes | mBio
Vibrio vulnificus is an aquatic pathogen that is capable of causing severe disease in humans. Previous studies have suggested that pathogenic isolates were restricted to certain phylogenetic lineages ...
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Karla Satchell @karlasatchell.bsky.social · 25/08/2025
Vibrio vulnificus is also the leading cause of seafood-borne death. I love oysters...I recommend po' boys with fried oysters, grilled, and stews. But always cooked, especially in the warm months of the year. Shrimp and other seafood also can be sources of infection. journals.lww.com/ajg/fulltext...
journals.lww.com
S3249 A Deadly Case of Vibrio vulnificus Bacteremia After... : Official journal of the American College of Gastroenterology | ACG
An abstract is unavailable.
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Karla Satchell @karlasatchell.bsky.social · 25/08/2025
Caution should be taken when walking in brackish waters and swimming. Common clinical cases include cuts while fishing, walking in shallow waters with small cuts on feet, and this one of infection while swimming with a new tattoo. casereports.bmj.com/content/2017...
casereports.bmj.com
Vibrio vulnificus septic shock due to a contaminated tattoo
We present a case of Vibrio vulnificus septic shock and cellulitis in a patient with chronic liver disease that occurred after obtaining a leg tattoo with subsequent seawater exposure in the Gulf of Mexico. Initial suspicion for V. vulnificus was high and he was started on empiric doxycycline and ceftriaxone at admission. Blood and wound cultures grew oxidase positive and comma-shaped Gram-negative rods ultimately confirmed to be V. vulnificus. Despite aggressive initial treatment, the patient developed septic shock and died. This case highlights the association of chronic liver disease and high mortality associated with infections of V. vulnificus . Health providers should remain vigilant for V. vulnificus infections in patients with chronic liver disease and raw oyster ingestion or seawater exposure.
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Karla Satchell @karlasatchell.bsky.social · 25/08/2025
The annual news blitz about danger this time year of Vibrio vulnificus is upon us. If you live in the Gulf or Atlantic areas, and particularly if you have liver disease, cancer, or immunosuppression, Vv is a danger. The disease is rare but death rates high, survivors have long hospitalizations 🧵
apnews.com
How to protect yourself from Vibrio vulnificus, the bacteria found in some coastal waters
States are warning beachgoers about a summertime surge in infections from a frightening, flesh-eating bacteria found in coastal waters.
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Karla Satchell @karlasatchell.bsky.social · 25/07/2025
Great time with my awesome Northwestern colleagues at #GRCMAST
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Reposted by Karla Satchell
Tracy Palmer @proftracypalmer.bsky.social · 25/07/2025
Congratulations to Mason Clark who won the @fems MicroLife poster prize at the Microbial Adhesion and Signal Transduction GRC!
A happy scientist holding a poster prize certificate
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Reposted by Karla Satchell
Gc Rox @gcrox.bsky.social · 24/07/2025
Northwestern Micro representing at the 2025GRC MAST conference in beautiful Newport. Great science, collegial people but there’s a cloud hanging over us all. ☁️
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Reposted by Karla Satchell
Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 09/07/2025
“NIH will introduce a cap on allowable publication costs starting in Fiscal Year (FY) 2026, ensuring that publication fees remain reasonable across the research ecosystem. The policy aims to curb excessive APCs & ensure the broad dissemination of research findings w/o unnecessary financial barriers”
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Reposted by Karla Satchell
Alt NIH Bluesky 🧪 @altnih4science.bsky.social · 07/07/2025
This is an event on Tuesday in the House of Representatives hosted by the minority Science committee, led by @lofgren.house.gov. Real question: why isn’t this being held in the evening and produced for TV and social media? There are production and storytelling resources in Congress.
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Reposted by Karla Satchell
Dorit Reiss @doritreiss.bsky.social · 15/06/2025
"A document [DHHS] sent to lawmakers to support Secretary Robert F. Kennedy Jr.’s decision to change U.S. policy on covid vaccines cites scientific studies that are unpublished or under dispute and mischaracterizes others." kffhealthnews.org/news/article... via @kffhealthnews.org
kffhealthnews.org
Kennedy’s HHS Sent Congress ‘Junk Science’ To Defend Vaccine Changes, Experts Say - KFF Health News
A look inside the Department of Health and Human Services document citing vaccine misinformation that could influence congressional perceptions.
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Reposted by Karla Satchell
Bill Grueskin @bgrueskin.bsky.social · 29/05/2025
RFK Jr's "MAHA" report is filled with references to studies that literally do not exist, or that completely misinterpret the studies' findings. “We did not publish a paper.. on this topic with that co-author group, or with that title,” says one cited researcher. www.notus.org/health-scien...
notus.org
The MAHA Report Cites Studies That Don’t Exist
The Trump administration’s “Make America Healthy Again” report misinterprets some studies and cites others that don’t exist, according to the listed authors.
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Karla Satchell @karlasatchell.bsky.social · 11/05/2025
Thanks to Northwestern Feinberg communications for writing this nice article on our recent work for the newsletter. @vibrio-vulnificus.bsky.social
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Karla Satchell @karlasatchell.bsky.social · 28/04/2025
Great new study by my excellent colleague @jutraslab.bsky.social on treatments for Luke’s disease
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Reposted by Karla Satchell
James Fallows @jfallows.bsky.social · 23/04/2025
To say it once more today: I think you'll be moved if you take 2 minutes to look through 269 institutions signed on here. Yes, still a few notable absences. (Where is Stanford?) But such an array of *presence.* Big and small. Public and private. World famous and barely known. Check them out.
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Karla Satchell @karlasatchell.bsky.social · 13/04/2025
Graduate student Jiexi Chen presented today in the emerging scientist session #ASBMB25 on her new paper on toxin binding N-glycans. She did a great job!!
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Karla Satchell @karlasatchell.bsky.social · 11/04/2025
Taking a break from the news in Bsky. Happy to share amazing study by student Jiexi Chen on Vibrio vulnificus MARTX toxin engagement of N-glycans and receptor L1CAM. First study on this toxin binding to cell surfaces. #vibrio #microsky #toxins www.science.org/doi/10.1126/...
science.org
Vibrio MARTX toxin binding of biantennary N-glycans at host cell surfaces
The large pore-forming toxin MARTX with broad tissue tropism binds the essential unit of N-glycans on eukaryotic cell membranes.
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Karla Satchell @karlasatchell.bsky.social · 11/03/2025
Was great to participate in this project designed to test robustness of AI ligand prediction but had a side benefit of crowd-sourced discovery of a SARS-CoV-2 helicase inhibitor
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Karla Satchell @karlasatchell.bsky.social · 06/03/2025
Hi @schakowsky.house.gov The weather is supposed to be nice for @standupforscience.bsky.social Rally for Science on the National mall. I am coming from Evanston, hope to see my rep there too!!
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Reposted by Karla Satchell
Chris Morran @themorrancave.bsky.social · 05/03/2025
Slashing IRS staff will end up costing the U.S. government. Multiple studies have shown that for every dollar spent by the IRS, the agency returns between $5 and $12. New @propublica.org by @andykroll.bsky.social
propublica.org
How DOGE’s Cuts to the IRS Threaten to Cost More Than DOGE Will Ever Save
The Trump administration claims gutting federal agencies will save money, but cutting the IRS means the government collects less taxes. “If you’re interested in the deficit and curbing it, why would y...
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Karla Satchell @karlasatchell.bsky.social · 05/03/2025
They can use AI bots on their side to save time/cost to replace editors, and now trying to normalize this behavior to get reviewers to volunteer more often so they can grow revenue.
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Karla Satchell @karlasatchell.bsky.social · 05/03/2025
Nature is responding to a critical flaw in their business model, they need to grow revenue to keep billionaire investors on board, but depend on volunteer peer reviewers. 1/n
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Karla Satchell @karlasatchell.bsky.social · 04/03/2025
Wonderful recognition! Hank gave great speech at ceremony on how service and faculty joining together is most important in challenging times
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Reposted by Karla Satchell
Tom Scriba @tomscriba.bsky.social · 03/03/2025
www.nejm.org/doi/full/10....
nejm.org
Order out of Chaos | NEJM
Eric Rubin comments on the effects of the raft of executive orders from the current administration on scientific research and public health.
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Reposted by Karla Satchell
Indivisible Chicago Alliance ❌👑 @indivisiblechicago.bsky.social · 26/02/2025
🗽🔬 STAND UP FOR SCIENCE. Chicago joins the nationwide movement to demand that our government fully support scientific research, which employs people, benefits our economy, and SAVES LIVES Join Indivisible Chicago & @standupforscience.bsky.social on Fri, March 7th, 12pm, Federal Plaza. Info/Sign-up:
mobilize.us
Stand up for Science · Indivisible Chicago
Science is for everyone–and benefits everyone. When the federal government supports scientific research through taxpayer funding, it fuels innovation, creates jobs, and sustains the world we live in...
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Alt CDC (they/them) @altcdc.altgov.info · 02/03/2025
It’s impossible to overstate how much damage Trump/Elon/Vought/RFKJ are doing to science in America. We need everyone who can to show up and demand action to save scientific research in this country. Scientists are trained to question everything which is why fascists always target them first.
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@LaBonneLaB @labonnelab.bsky.social · 27/02/2025
This is a crisis threatening the US scientific research enterprise which drives our wealth, health and prosperity. Make that clear to anyone and everyone you know
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Dan Diamond @ddiamond.bsky.social · 26/02/2025
Elon Musk said DOGE made a mistake by cutting USAID’s Ebola prevention but it had been “restored.” That’s not true, current and former officials told me and @johnphudson.bsky.social. “There have been no efforts to ‘turn on’” Ebola prevention, said Nidhi Bouri, who oversaw team until January.
washingtonpost.com
Musk claims DOGE ‘restored’ Ebola prevention effort. Officials disagree.
USAID’s initiatives to fight Ebola and other diseases have been gutted, current and former agency officials said.
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Karla Satchell @karlasatchell.bsky.social · 27/02/2025
I am going to join the Stand Up for Science in DC! Friends DM if will be there too. Chicago folks, will be missing you at Federal square #standupforscience2025
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Senator Patty Murray @murray.senate.gov · 23/02/2025
Gregg is a former Marine and Forest Service ranger. He's saved the lives of hikers dangling off a cliff or going through cardiac arrest, and he's bravely fought forest fires to save small rural towns. 100% of his salary is paid by WA state. Elon fired him. Share his story.
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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 17/02/2025
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Harmit Singh Malik @harmitmalik.bsky.social · 14/02/2025
With measles flaring up and threatening to become a significant concern and H5N1 knocking on the door, today seems like a perfect day to fire all the fellows and postdocs working at the CDC WTAF?!
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Kyle Cheney @kyledcheney.bsky.social · 10/02/2025
JUST IN: A federal judge in Massachusetts has blocked the Trump administration's rate change to NIH grants. storage.courtlistener.com/recap/gov.us...
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Karla Satchell @karlasatchell.bsky.social · 10/02/2025
Why does Trump care about a corrupt Democrat Illinois ex-governor? I suppose he is upset there is precedence that is illegal for governors to sell empty senate seats to highest bidder.
apnews.com
Trump is expected to pardon ex-Illinois Gov. Rod Blagojevich 5 years after commuting his sentence
President Donald Trump will pardon former Illinois Gov. Rod Blagojevich. That's according to a person familiar with his plans who was not authorized to speak publicly.
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bluestatedon.bsky.social @bluestatedon.bsky.social · 10/02/2025
bsky.app/profile/greg...
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Daniel Gorelick @danielgorelick.bsky.social · 10/02/2025
Trainees who applied for an NIH diversity fellowship whose applications were withdrawn/not being reviewed, there's a NYTimes reporter who wants to talk, especially interested in applicants with disabilities. DM me & I'll put you in touch, will keep all contact confidential. Please amplify
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Healthcare-Global @healthcare-global.bsky.social · 08/02/2025
www.bloomberg.com/news/article...
bloomberg.com
Outcry as NIH Plans $4 Billion in Cuts to Reimburse Scientists
The National Institutes of Health plans to cut billions of dollars in reimbursements to medical researchers, a move scientists warn could jeopardize their work in advancing cures for diseases.
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Carl T. Bergstrom @carlbergstrom.com · 08/02/2025
1. Today the NIH director issued a new directive slashing overhead rates to 15%. I want to provide some context on what that means and why it matters. grants.nih.gov/grants/guide...
grants.nih.gov
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
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