iiinova — where your digital self keeps evolving

Reposted by Jeremy Jacobs, MD, MHS, FASCP

MedPage Today @medpagetoday.com · 27/01/2026

Nearly half of the CDC databases that traditionally had monthly updates experienced unexplained pauses in 2025, with most of the affected being databases that track vaccination information, according to a review. @jwjacobs12.bsky.social @idsainfo.bsky.social www.medpagetoday.com/infectiousdi...

medpagetoday.com

CDC Stopped Updating Key Vaccine, Infectious Disease Databases in 2025

The inaction 'demonstrates a profound disregard for human life,' says IDSA leader

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

JAMA @jama.com · 25/12/2025

💬 Editorial: While restrictive transfusion remains standard, TOP trial results indicate some cardiac patients may benefit from a tailored approach based on clinical factors. ja.ma/4p90DFW

A JAMA (Journal of the American Medical Association) article titled "Postoperative Transfusion in Patients at High Cardiac Risk Evidence, Uncertainty, and Nuance" by Jeremy W. Jacobs, MD, MHS; Evan M. Bloch, MBChB, MS. Published online November 8, 2025.

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Raza @transfusion.health · 26/08/2025

“This trial adds to the growing body of evidence suggesting no clinically meaningful benefit to albumin administration in the resuscitation of septic patients”

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Jeremy Jacobs, MD, MHS, FASCP @jwjacobs12.bsky.social · 25/08/2025

Our most recent article hits particularly close to home for me. Had the OBBB passed 10 years ago, it’s unlikely that I would have been able to attend medical school. The new changes threaten to “make the rich, richer”.

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

The BMJ @bmj.com · 18/08/2025

The Annals of Internal Medicine has refused US health secretary Robert F Kennedy Jr’s demand to retract a study that found that vaccines containing the adjuvant aluminium hydroxide did not increase the incidence of 50 chronic disorders, including autism and asthma www.bmj.com/content/390/...

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

PLOS Climate @plosclimate.org · 21/07/2025

New Opinion article by @jwjacobs12.bsky.social and Shazia Khan: "Erasing the evidence: United States climate rollbacks and the implications for public health" journals.plos.org/climate/arti...

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Raza @transfusion.health · 18/06/2025

Blood is shared across legal borders to save lives. Equitable and efficient movement of blood is guided by science and justice and must be insulated from ideologically motivated practices, argue co-authors @jwjacobs12.bsky.social @aabbupdates.bsky.social onlinelibrary.wiley.com/doi/10.1111/...

onlinelibrary.wiley.com

Blood Borders: State laws, vaccine misinformation, and the threat to the United States blood supply

Click on the article title to read more.

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Jeremy Jacobs, MD, MHS, FASCP @jwjacobs12.bsky.social · 23/05/2025

In this Nature Medicine commentary @drgsbooth1.bsky.social and I discuss how the current political environment in the USA, including the weaponization of immigration enforcement, is impacting global scientific research, and the implications for science. www.nature.com/articles/s41...

nature.com

How US politics is undermining global science

Nature Medicine - How US politics is undermining global science

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Michael Coyle @oplopanax.ca · 09/04/2025

In other words, the US government has suspended free speech.

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Jeremy Jacobs, MD, MHS, FASCP @jwjacobs12.bsky.social · 09/04/2025

Check out our recent viewpoint in @jama.com. The appointment of David Geier to lead the “vaccine and autism link” study, the forced resignation of Peter Marks at the FDA, and the overall leadership of RFK Jr. and Trump are literally killing Americans. We must resist this new world.

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Benjamin Mazer @mazer.us · 07/04/2025

The Health Secretary is promoting quack doctors in the midst of a measles outbreak and literally nothing was more predictable.

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Gabriel Winant @gabrielwinant.bsky.social · 10/03/2025

Here is an open letter signed from UChicago AAUP signed by over 200 faculty to our administration on what we believe this moment requires: uchicagoaaup.wordpress.com

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Carl Quintanilla @carlquintanilla.bsky.social · 28/02/2025

EU foreign policy chief: “.. Today, it became clear that the free world needs a new leader.” @kajakallas.bsky.social

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Raza @transfusion.health · 29/01/2025

In this issue of NEJM Evidence, @jwjacobs12.bsky.social and I interpret the recent individual-patient meta-analysis for RBC transfusion in myocardial infarction by Carson et al and make a case for nuanced interpretation evidence.nejm.org/doi/full/10.... #medsky #transfusion

evidence.nejm.org

Transfusion Strategies in Myocardial Ischemia — Treat Patients, Not Numbers

Consider a relatively common clinical scenario: a 55-year-old man arrives in the emergency department after experiencing crushing retrosternal chest pain while shoveling the first snowfall of winte...

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Raza @transfusion.health · 17/12/2024

Our correspondence with @natureportfolio.bsky.social advocating that scholarly journals support direct link-sharing to #Bluesky amidst the exodus of academic communities from X (formerly Twitter) @drgsbooth1.bsky.social @jwjacobs12.bsky.social @path-brian.bsky.social www.nature.com/articles/d41...

Screenshot of correspondence with @natureportfolio.bsky.social advocating that all scholarly journals support direct link-sharing to Bluesky amidst the exodus of many academic communities from X (formerly Twitter)

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Jeremy Jacobs, MD, MHS, FASCP @jwjacobs12.bsky.social · 05/12/2024

Excited to share our recent study in which we assessed whether iodinated radiocontrast media (as might be given for a CT scan) interferes with ADAMTS13 activity via the gold standard FRET method - it doesn’t, though read the open access paper for caveats. academic.oup.com/ajcp/advance...

academic.oup.com

Evaluating the potential for iodinated radiocontrast agents to interfere with ADAMTS13 activity testing via fluorescence resonance energy transfer methodology

AbstractObjectives. Fluorescence resonance energy transfer (FRET)–based ADAMTS13 activity assays are critical for the diagnosis of thrombotic thrombocytope

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Raza @transfusion.health · 05/12/2024

Tranexamic acid did not prevent bleeding or increase clotting in this ~600 patient RCT of heme malignancy patients (TXA was given 1 g IV every 8 hours or 1.5 g orally every 8 hours)🤷🏽‍♂️ Which is too bad--we don't have a tonne to offer these patients.. :( www.thelancet.com/journals/lan... #transfusion

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Bluesky @bsky.app · 03/12/2024

Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Carlos M Herrera @cmhmaliani.bsky.social · 02/12/2024

Good news, Altmetric has now started watching BlueSky for mentions of publications. And by the way, provides an easy comparison between this and the old site for a recent preprint of mine which I posted simultaneousl at both. Numbers speak by themselves !

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Ryan Elliott @ryanelliott.bsky.social · 01/12/2024

🩸Platelets! Lifespan 7-10 days 150-450 × 10⁹/L Stimulated by TPO 1/3 sequestered in spleen Receptors: GpIIbIIIa -> fibrinogen GPIb-IX-V -> vWF P2Y12 -> ADP Granules: Alpha = fibrinogen, vWF, V, VEGF, PF4, PDGF, P-selectin Dense = ADP, Ca, Serotonin #hemesky #MedSky van der Meijden et al, 2019

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Raza @transfusion.health · 01/12/2024

Wonderful article by my mentor showing cognitive biases persist in AI chatbots, replicates known studies on biases in human and AI LLMs for comparison. Evidence that LLMs are inheriting some of our biases, in some cases quite strongly so ai.nejm.org/doi/full/10.... #mlsky #ai

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Jeremy Jacobs, MD, MHS, FASCP @jwjacobs12.bsky.social · 19/11/2024

A fantastic person/physician/researcher to follow!

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Reposted by Jeremy Jacobs, MD, MHS, FASCP

Brian D. Adkins @path-brian.bsky.social · 17/11/2024

How do we screen for hemoglobin abnormality in the US? -All state newborn screens evaluate hemoglobin -pediatric-age immigrants often get newborn when they come to US -Thalassemia trait often identified in pregnant patients or patients with persistent microcytosis after correcting iron deficiency

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