Microplastics might clog up immune cells, preventing them from fighting infections and clearing away dead cells, as well as reducing sperm counts.

Cellular clean up by immune cells and how early-life fructose exposure leads to neurodevelopmental problems.

Background Acetaminophen is the most commonly used over-the-counter pain and fever medication taken during pregnancy, with > 50% of pregnant women using acetaminophen worldwide. Numerous well-designed...

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In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.

Nature - Exposure of mice to high fructose during gestation or early postnatal life causes decreased microglial phagocytosis during brain development and leads to anxiety-like behaviour in...

A new laboratory study from MSK is shedding light on the mechanisms by which high fructose consumption early in life may directly impact brain development and increase the risk of anxiety disorders la...

Nature Communications - Tissue-resident macrophages (TRM) are important mediators of local immunity. Here the authors show that the deficiency or inhibition of a kinase, WNK1, unlinks macrophage...

New study shows that a specific growth factor causes early-stage immune cells (macrophage precursors) to ‘drink’, which activates a special enzyme. This cell drinking and enzyme activation determines ...