Sign in

Dr Jacob Scadden

@jscadden.bsky.social
33 followers 43 following 6 posts

Postdoctoral researcher at the University of New South Wales. Studying the evolution of the bacterial flagellar filament.

PostsRepliesMedia
Reposted by Dr Jacob Scadden
Animalcules @bacteriophile.bsky.social · 21/08/2026
journals.plos.org/plospathogen... #microsky
journals.plos.org
Phage-encoded sRNA counteracts xenogeneic silencing in pathogenic E. coli
Author summary Horizontal gene transfer allows bacteria to acquire new traits, including many of the genes that make pathogens harmful. However, newly acquired DNA can also disrupt normal cellular fun...
021
Reposted by Dr Jacob Scadden
Matt Baker @phatmattbaker.bsky.social · 21/08/2026
A great trip to Auckland for #ISME20. I came out feeling much more like a microbial ecologist. So many connections across scales: from flagellar motors to spatial structure, communities and ecosystems. Great science, people & ideas!
151
Dr Jacob Scadden @jscadden.bsky.social · 29/05/2026
🚨New paper alert 🚨 Our review is published now in @cp-trendsbiotech.bsky.social. This review focuses on the use of flagellin in biotechnology. 🔬🦠🧪 Congratulations to Divyangi Pandit on the first paper of her PhD and to @phatmattbaker.bsky.social for his support. www.cell.com/trends/biote...
cell.com
Flagellin beyond motility: exploiting flagellar filaments in biotechnology
Flagellin is the structural protein of the bacterial flagellar filament, an extracellular propeller that rotates to drive swimming in many bacteria. The structure of flagellin allows for outer domain ...
100
Reposted by Dr Jacob Scadden
Microbiology Society @microbiologysociety.org · 23/02/2026
Microbiology’s most read research article of 2025 covers research on the nisin O cluster with a potential for future antimicrobial therapy. Check out the article here: doi.org/10.1099/mic.0.001531
Fig 1: ACT cluster analysis of the nisin O-like BGCs and the B. producta SCSK cluster nucleotide sequences., Scadden et al.
122
Reposted by Dr Jacob Scadden
JAMS Sydney @jamsorgsyd.bsky.social · 04/02/2026
🧫 JAMS Sydney is back! 🧫 We’re kicking off 2026 with an Archaea Special 🔬 📅 24 February ⏰ 6–8 pm 📍 Shakespeare Hotel, 200 Devonshire St, Surry Hills New year, new venue, and a deep dive into one of the most fascinating domains of life. 🎤 Speaker details coming soon — stay tuned! #JAMSSydney
032
Reposted by Dr Jacob Scadden
ASM @aussocmic.bsky.social · 13/11/2025
Registrations for Australia's premier Microbiology conference are now open. www.theasmmeeting.org.au/registration
123
Dr Jacob Scadden @jscadden.bsky.social · 29/10/2025
Thanks to @jamsorgsyd.bsky.social for the opportunity to talk about the evolution of the bacterial flagellar filament to a fantastic crowd. It is always a pleasure to tell this story and showcase the amazing diversity, evolution and adaptation of bacterial flagella! 🦠🔬
120
Reposted by Dr Jacob Scadden
JAMS Sydney @jamsorgsyd.bsky.social · 23/10/2025
Come along and join us at the Keg & Brew for our final monthly of the year! Super keen to hear some amazing talks about all things microbiology🤩🧬 #microbiology #JAMSmicro #science #seminar #networking #biology #research
002
Reposted by Dr Jacob Scadden
Nature Microbiology @natmicrobiol.nature.com · 22/09/2025
#NewResearch Structure of a functional archaellum in bacteria of the Chloroflexota phylum #MicroSky @archaellum.bsky.social @sshamphavi.bsky.social @loumollat.bsky.social ‬ @mariejoest.bsky.social @sgribaldo.bsky.social www.nature.com/articles/s41...
nature.com
Structure of a functional archaellum in Bacteria of the Chloroflexota phylum - Nature Microbiology
Bona fide gene clusters for archaella are widespread across a bacterial phylum and encode functional motility machinery.
0178
Dr Jacob Scadden @jscadden.bsky.social · 28/08/2025
Thanks to the @arccoesb.bsky.social for organising a great ECR workshop on grant writing! Some great tips into grant writing and insights into the decision making process. A big thank you to all the panel members for taking time to help during the 1:1 sessions. #ECR #Grant #Academia
110
Dr Jacob Scadden @jscadden.bsky.social · 12/08/2025
🚨New Paper Alert🚨Our latest paper is published now in the Journal of Bacteriology @asm.org!🦠🔬🏃 A huge thanks to all the co-authors (Matthew Baker, Divyangi Pandit, Pietro Ridone and Yoshiyuki Sowa) for all their hard work! @unswbabs.bsky.social #flagella #chimera journals.asm.org/doi/10.1128/...
journals.asm.org
Rescue of bacterial motility using two- and three-species FliC chimeras | Journal of Bacteriology
Flagellin is a key protein forming the filament of the bacterial flagellar motor which powers most bacterial swimming. Flagellin can have hypervariable domains which can alter motility in different en...
021
Reposted by Dr Jacob Scadden
Matt Baker @phatmattbaker.bsky.social · 15/06/2025
Out this weekend in @ismepublications.bsky.social We looked at 10,000 species to map the diversity and history of the bacterial #flagellar motor across the tree of life. Lots of (re)analysis , especially from Jamiema Sara Philip @unswbabs.bsky.social academic.oup.com/ismej/advanc...
34013
Dr Jacob Scadden @jscadden.bsky.social · 17/06/2025
I'm excited to share that our latest research, "Mapping the loss of flagellar motility across the tree of life", in which I was a co-author, has been published in @isme-microbes.bsky.social Journal! 🧪🦠 Huge thanks to all the co-authors! 📖 Read the full paper here: academic.oup.com/ismej/advanc...
academic.oup.com
Mapping the loss of flagellar motility across the tree of life
Abstract. Bacterial swimming is mostly powered by the bacterial flagellar motor and the number of proteins involved in the flagellar motor can vary. Quanti
010
Reposted by Dr Jacob Scadden
apreston243.bsky.social @apreston243.bsky.social · 10/02/2025
New paper alert! The nisin O biosynthetic gene cluster lacks a leader-peptide cleaving protease but is distributed across different gut-associated genera. @microbiologysociety.org @narbadlab.bsky.social www.microbiologyresearch.org/content/jour...
microbiologyresearch.org
The nisin O cluster: species dissemination, candidate leader peptide proteases and the role of regulatory systems
Nisin O is an antimicrobial peptide encoded by the human gut bacterium Blautia obeum A2-162 which has antimicrobial activity against clinically relevant organisms. The nisin O biosynthetic gene cluste...
031