New paper from my PhD work on the E3 ubiquitin ligase HUWE1 in lung cancer, now out in Cell Death & Disease.
We show that HUWE1 is required for KRAS-driven tumour growth and that targeting it induces tumour cell senescence and tumour regression.
🔗 www.nature.com/articles/s41...
nature.com
The E3 ubiquitin ligase HUWE1 is required for KRAS-induced lung cancer - Cell Death & Disease
Cell Death & Disease - The E3 ubiquitin ligase HUWE1 is required for KRAS-induced lung cancer