New research illuminated mechanisms of bacterial protein production, transport, & folding, while better understanding molecular communities.

In-cell cryo-electron tomography (cryo-ET) combined with proteomics, integrative structural modeling, and bioinformatics enables discovery and functional annotation of uncharacterized proteins. In the...

Cryo-electron tomography (cryo-ET) resolves and quantifies an almost complete view of bacterial translation, revealing how gene expression machineries coordinate across the processes of transcription,...

We use sub-2 Å single-particle analysis and analytical contrast transfer function modeling to show that the Volta phase plate (VPP) boosts low-frequency signal relevant for cryo-electron tomography (c...

Cryo-electron tomography has emerged as powerful technology for in-cell structural biology, and in combination with breakthroughs in protein structure prediction, offers a unique opportunity for illum...

Nuclear pore complexes (NPCs) bridge across the nuclear envelope and mediate nucleocytoplasmic exchange. They consist of hundreds of nucleoporin build…